Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Yumin, Hu"'
Autor:
Yongjie Deng, Yao Yao, Yanni Wang, Tiantian Yu, Wenhao Cai, Dingli Zhou, Feng Yin, Wanli Liu, Yuying Liu, Chuanbo Xie, Jian Guan, Yumin Hu, Peng Huang, Weizhong Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Untargeted metabolomic analysis using mass spectrometry provides comprehensive metabolic profiling, but its medical application faces challenges of complex data processing, high inter-batch variability, and unidentified metabolites. Here, we
Externí odkaz:
https://doaj.org/article/dd46ce79e57a443483095924995ce75a
Autor:
Jiang-jiang Li, Tiantian Yu, Peiting Zeng, Jingyu Tian, Panpan Liu, Shuang Qiao, Shijun Wen, Yumin Hu, Qiao Liu, Wenhua Lu, Hui Zhang, Peng Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mutations in isocitrate dehydrogenases (IDH) are oncogenic events due to the generation of oncogenic metabolite 2-hydroxyglutarate. However, the role of wild-type IDH in cancer development remains elusive. Here we show that wild-type IDH2 is
Externí odkaz:
https://doaj.org/article/ff8b8155af5c47038fa51f45d4a09483
Autor:
Mengqi Yang, Jiaxin Liu, Jianan Li, Shijun Wen, Yumin Hu, Wenhua Lu, Jinyun Liu, Peng Huang, Panpan Liu
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103245- (2024)
Since the survival of lymphoma patients who experience disease progression or relapse remains very poor, new therapeutic approaches and effective drugs are urgently needed. Here we show that auranofin (AF), an anti-rheumatoid drug thought to inhibit
Externí odkaz:
https://doaj.org/article/3dd33dfbec784a21b763548c4cf6e84b
Autor:
Yao Yao, Xueping Wang, Jian Guan, Chuanbo Xie, Hui Zhang, Jing Yang, Yao Luo, Lili Chen, Mingyue Zhao, Bitao Huo, Tiantian Yu, Wenhua Lu, Qiao Liu, Hongli Du, Yuying Liu, Peng Huang, Tiangang Luan, Wanli Liu, Yumin Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Differential diagnosis of pulmonary nodules detected by computed tomography (CT) remains a challenge in clinical practice. Here, we characterize the global metabolomes of 480 serum samples including healthy controls, benign pulmonary nodules
Externí odkaz:
https://doaj.org/article/981ab3f998bb4fd982489ee53a30a6c1
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Mitochondria are promising drug target for cancer treatment. We previously demonstrated that a bi-gold compound BGC2a was more potent than the mono-gold drug auranofin in suppressing cancer cells due to increased gold atom number that led to higher d
Externí odkaz:
https://doaj.org/article/c19827921137433ea5c15bb0b312c67d
Autor:
Rui Liu, Panpan Liu, Huichang Bi, Jianhua Ling, Huiqin Zhang, Mingquan Zhang, Yumin Hu, Paul J Chiao, Peng Huang, Jinyun Liu
Publikováno v:
Cancer Communications, Vol 43, Iss 2, Pp 285-289 (2023)
Externí odkaz:
https://doaj.org/article/8b58280c81754fb3b65995d14a7e3529
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Background Breast cancer is the fastest-growing cancer among females and the second leading cause of female death. At present, targeted antibodies combined with hyperthermia locally in tumor has been identified as a potential combination the
Externí odkaz:
https://doaj.org/article/29908c7db8e74db288275c1c05c1420f
Autor:
Xiao Deng, Bin Chen, Yixuan Chen, Lu Jiang, Yumin Hu, Yang Yang, Xiangmin Rong, Liang Peng, Qingru Zeng
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 239, Iss , Pp 113658- (2022)
Devising a low-cost and effective strategy to reduce Cd contamination of brown rice is critical to achieve the safe production of rice grain for human consumption. Accordingly, here field experiments were conducted at two sites to evaluate the effect
Externí odkaz:
https://doaj.org/article/d80cb06669b6489c8ddac1a25d238fcf
Autor:
Chenying Lu, Shiji Fang, Qiaoyou Weng, Xiuling Lv, Miaomiao Meng, Jinyu Zhu, Liyun Zheng, Yumin Hu, Yang Gao, Xulu Wu, Jianting Mao, Bufu Tang, Zhongwei Zhao, Li Huang, Jiansong Ji
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Cancer cells primarily utilize aerobic glycolysis for energy production, a phenomenon known as the Warburg effect. Increased aerobic glycolysis supports cancer cell survival and rapid proliferation and predicts a poor prognosis in
Externí odkaz:
https://doaj.org/article/bb3c9990e700478fbb558002561e6c30
Autor:
Xiaoxia Liu, Yanyu Zhang, Yi Han, Wenhua Lu, Jing Yang, Jingyu Tian, Peng Sun, Tiantian Yu, Yumin Hu, Hui Zhang, Peng Huang, Panpan Liu
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1028-1044 (2020)
B‐cell non‐Hodgkin's lymphoma (NHL) is a class of heterogeneous diseases with variable clinical outcomes. Immunosuppression is particularly common in the subtypes of lymphoma with poor prognosis, but the underlying mechanism remains unclear. Usin
Externí odkaz:
https://doaj.org/article/83524234b045452a9076785f29226982