Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yumiko Nishinaka"'
Autor:
Narakorn Khunweeraphong, Shushi Nagamori, Pattama Wiriyasermkul, Yumiko Nishinaka, Printip Wongthai, Ryuichi Ohgaki, Hidekazu Tanaka, Hideyuki Tominaga, Hiroyuki Sakurai, Yoshikatsu Kanai
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 4, Pp 368-380 (2012)
System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2
Externí odkaz:
https://doaj.org/article/b0c960fcf96d4847a58f941dfc229c89
Autor:
Kazuaki Takafuji, Yumiko Nishinaka, Virginia Nunes, Ryuichi Ohgaki, Shushi Nagamori, Pattama Wiriyasermkul, Susanna Bodoy, Meritxell Espino Guarch, Suguru Okuda, Manuel Palacín, Hirohisa Okuyama, Yoshikatsu Kanai, Saya Nakagomi, Kenjiro Tadagaki, Junko Kurokawa
Heterodimeric amino acid transporters play crucial roles in epithelial transport, as well as in cellular nutrition. Among them, the heterodimer of a membrane protein b(0,+)AT/SLC7A9 and its auxiliary subunit rBAT/SLC3A1 is responsible for cystine rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88d00c24d99c4dac1f1015357199b18
https://europepmc.org/articles/PMC4725474/
https://europepmc.org/articles/PMC4725474/
Autor:
Shushi Nagamori, Narakorn Khunweeraphong, Hiroyuki Sakurai, Ryuichi Ohgaki, Hideyuki Tominaga, Yumiko Nishinaka, Hidekazu Tanaka, Yoshikatsu Kanai, Pattama Wiriyasermkul, Printip Wongthai
Publikováno v:
Journal of Pharmacological Sciences, Vol 119, Iss 4, Pp 368-380 (2012)
Journal of Pharmacological Sciences
Journal of Pharmacological Sciences
System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is responsible for the nutrient uptake in cancer cells, whereas L-type amino acid transporter 2 (LAT2
Autor:
Michiyuki Maeda, Yumiko Nishinaka, Kisato Nosaka, M. K. Ahsan, Yong-Chul Kim, Junji Yodoi, Masao Matsuoka, Yoshimi Yamaguchi, Hiroshi Masutani
Publikováno v:
Oncogene. 25:2181-2191
The transition from interleukin-2 (IL-2)-dependent to IL-2-independent growth is considered one of the key steps in the transformation of human T-cell leukemia virus type-I (HTLV-I)-infected T cells. The expression of thioredoxin-binding protein-2 (T
Autor:
Wen-Hua Lee, Yumiko Nishinaka, Hiroshi Hiai, Shinya Akatsuka, Hiroshi Masutani, Than Tin Aung, Shinya Toyokuni, Tomoyuki Shirase, Khokon Kumar Dutta, Junji Yodoi, Yoshihiro Yamada
Publikováno v:
Laboratory Investigation. 85:798-807
Thioredoxin is a major component of thiol-reducing system. Recently, we identified thioredoxin-binding protein-2 (TBP-2) as a negative regulator of thioredoxin. Here, we report the role of TBP-2 in oxidative renal tubular injury and the subsequent ca
Autor:
Junji Yodoi, Aoi Son, Yumiko Nishinaka, Yasuyuki Ishii, Shingo Suzuki, Norihiko Kondo, Hiroshi Masutani, Shinae Kizaka-Kondoh, Junko Sakakura-Nishiyama, Yoshiyuki Matsuo, Masami Kojima, Yoshimi Yamaguchi
Publikováno v:
Archives of Biochemistry and Biophysics. 423:81-87
Various proteins sharing thioredoxin (Trx)-like active site sequences (Cys-Xxx-Xxx-Cys) have been found and classified in the Trx superfamily. Among them, transmembrane Trx-related protein (TMX) was recently identified as a novel protein possessing a
Autor:
Toshinori Nakayama, Junji Yodoi, Yasuyuki Ishii, Junko Sakakura-Nishiyama, Yong-Won Kwon, Yumiko Nishinaka, Norihiko Kondo, Aoi Son, Masaki Tanito, Masaru Taniguchi, Yoshiyuki Matsuo
Publikováno v:
Immunology Letters. 92:143-147
Thioredoxin (TRX) superfamily proteins that contain a conserved redox-active site -Cys-Xa.a.-Xa.a.-Cys- includes proinflammatory cytokine, macrophage migration inhibiting factor (MIF) and the immune regulatory cytokine, glycosylation inhibiting facto
Autor:
Yasuyuki Ishii, Akira Nishiyama, Kaimul Ahsan, Shinichi Oka, Yumiko Nishinaka, Hiroshi Masutani, Junji Yodoi, Hajime Nakamura, Michiyuki Maeda, Yukie Nakayama
Publikováno v:
Cancer Research. 64:1287-1292
Human T-cell leukemia virus type I (HTLV-I) is the causative agent of adult T-cell leukemia (ATL). However, the low incidence of ATL among HTLV-I-infected carriers, together with a long latent period, suggests that multiple host-viral events are invo
Autor:
Junji Yodoi, Masaki Tanito, Yong-Won Kwon, Yasuyuki Ishii, Norihiko Kondo, Hajime Nakamura, Yumiko Nishinaka, Hiroyuki Horita
Publikováno v:
The Journal of Immunology. 172:442-448
Thioredoxin (TRX) is released from various types of mammalian cells despite no typical secretory signal sequence. We show here that a redox-active site in TRX is essential for its release from T lymphocytes in response to H2O2 and extracellular TRX r
Autor:
Shushi Nagamori, Pattama Wiriyasermkul, Noriyoshi Isozumi, Yasuhiro M. Umemura, Yoshikatsu Kanai, Yumiko Nishinaka
Publikováno v:
Biophysical Journal. 106(2)
Transporters utilize electrochemical gradients across membranes to translocate their substrates through the membranes. Many eukaryotic plasma membrane symporters transport substrates in a Na+-dependent manner by using an electrochemical Na+ gradient