Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yumiko Komatsu"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract RNA virus-based episomal vector (REVec) is an emerging viral vector system that mediates long-term stable gene expression in variety of cell types in vitro. However, little is known about its tissue tropism and persistence of gene expression
Externí odkaz:
https://doaj.org/article/6e878e2e13f3437185c1a461dc15a8d6
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160529 (2016)
Oncogenic activation of Ras/MEK downregulates the expression of interferon regulatory factor 1 (IRF1), which is a prerequisite for oncolytic viruses to replicate in cancer cells [1]. Moreover, restoration of IRF1 expression is essential to induce apo
Externí odkaz:
https://doaj.org/article/512da92d514a442c92212f1bb5313e90
Autor:
Nicholas A Fairbridge, Thomas M Southall, D Craig Ayre, Yumiko Komatsu, Paula I Raquet, Robert J Brown, Edward Randell, Christopher S Kovacs, Sherri L Christian
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141966 (2015)
CD24 is a glycophosphatidylinositol (GPI)-linked cell surface receptor that is involved in regulating the survival or differentiation of several different cell types. CD24 has been used to identify pre-adipocytes that are able to reconstitute white a
Externí odkaz:
https://doaj.org/article/75fe5780a6604ca9b88ad6db9faedaca
Autor:
Ahmed A Mostafa, Dianne Codner, Kensuke Hirasawa, Yumiko Komatsu, Matthew N Young, Viktor Steimle, Sheila Drover
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87377 (2014)
The coordinate regulation of HLA class II (HLA-II) is controlled by the class II transactivator, CIITA, and is crucial for the development of anti-tumor immunity. HLA-II in breast carcinoma is associated with increased IFN-γ levels, reduced expressi
Externí odkaz:
https://doaj.org/article/1e3ac2d631034a119e7a05f30f501be1
Autor:
Sherri L Christian, Dong Zu, Maria Licursi, Yumiko Komatsu, Theerawat Pongnopparat, Dianne A Codner, Kensuke Hirasawa
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44267 (2012)
Certain oncolytic viruses exploit activated Ras signaling in order to replicate in cancer cells. Constitutive activation of the Ras/MEK pathway is known to suppress the effectiveness of the interferon (IFN) antiviral response, which may contribute to
Externí odkaz:
https://doaj.org/article/f67d69041eba42c5b2a0552cd9ba766b
Autor:
Shota Takumi, Kairi Hashimoto, Masaru Tomioka, Mina Sato, Weijie He, Yumiko Komatsu, Shunji Aoki, Ryuji Ikeda, Kazuhiro Shiozaki, Tatsuhiko Furukawa, Masaharu Komatsu
Publikováno v:
Planta Medica. 89:616-623
The hepatotoxin microcystin-LR is a strong inhibitor of serine/threonine protein phosphatase (PP) 1 and PP2A. The onset of its cytotoxicity depends on its selective uptake via the hepatocyte uptake transporters, organic anion transporting polypeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5eeb4517b6ebd1eb7d894be2f5c33c47
https://doi.org/10.1055/a-1978-8768
https://doi.org/10.1055/a-1978-8768
Publikováno v:
J Virol
An RNA virus-based episomal vector (REVec) based on Borna disease virus 1 (BoDV-1) is a promising viral vector that achieves stable and long-term gene expression in transduced cells. However, the onerous procedure of reverse genetics used to generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263bb49da398f26cd6fac07c8486541e
https://pubmed.ncbi.nlm.nih.gov/34406860
https://pubmed.ncbi.nlm.nih.gov/34406860
Autor:
Yumiko Komatsu, Yasuhiro Ikeda, Keizo Tomonaga, Akiko Makino, Tomoya Tokunaga, Hidetoshi Sakurai, Dan Takeuchi, Tomoyuki Honda
Publikováno v:
Molecular Therapy. Methods & Clinical Development
A gene delivery system that allows efficient and safe stem cell modification is critical for next-generation stem cell therapies. An RNA virus-based episomal vector (REVec) is a gene transfer system developed based on Borna disease virus (BoDV), whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c52b47ece38e587d3ec50831f0d052de
https://doi.org/10.1016/j.omtm.2019.05.010
https://doi.org/10.1016/j.omtm.2019.05.010
Autor:
Koji Takenaka1, Yumiko Komatsu2
Publikováno v:
Journal of Health Psychology Research. 2018 Special issue, Vol. 30, p99-106. 8p.
Autor:
Yumiko Komatsu, Ryo Komorizono, Keizo Tomonaga, Takehiro Kanda, Takeshi Noda, Akiko Makino, Madoka Sakai, Yoko Fujita
Publikováno v:
J Virol
An RNA virus-based episomal vector (REVec) whose backbone is Borna disease virus 1 (BoDV-1) can provide long-term gene expression in transduced cells. To improve the transduction efficiency of REVec, we evaluated the role of the viral envelope glycop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d641644f66dd07a8b58be0fd569a5114
https://europepmc.org/articles/PMC8092845/
https://europepmc.org/articles/PMC8092845/
