Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yumiko Kanno"'
Publikováno v:
Immunology Letters. 224:21-27
Intestinal IgA is induced by microbes and food antigens. Peyer's patches (PPs) are known as one of the inductive sites for intestinal IgA production. However, the precise mechanism of IgA induction is as yet unknown. IgA secretion was induced from Ig
Publikováno v:
Immunology Letters. 211:53-59
Peyer's patches (PPs) are inductive sites for IgA production; however, the induction mechanism of IgA remains largely unknown. We found that the activated phenotypes of isotype-switched PP B cells were more abundant than those of splenic B cells. Imm
Publikováno v:
Scandinavian Journal of Immunology.
CD4+ CD25+ Foxp3+ regulatory T cells (Tregs) are highly sensitive to IL-2, one of the many cytokines produced during immune responses, for their development, survival and functions. Although the effects of IL-2 administration on Tregs in vivo are wel
Publikováno v:
Immunology letters. 224
Intestinal IgA is induced by microbes and food antigens. Peyer's patches (PPs) are known as one of the inductive sites for intestinal IgA production. However, the precise mechanism of IgA induction is as yet unknown. IgA secretion was induced from Ig
Publikováno v:
Clin Exp Immunol
Summary Heparin is a widely used anti-coagulant that enhances anti-thrombin (AT) activity. However, heparin also suppresses immune and inflammatory responses in various rodent models and clinical trials, respectively. The mechanism by which heparin s
Publikováno v:
Cellular Immunology. 323:41-48
Intestinal immunoglobulins (Igs) protect against microbes. However, the regulation of intestinal Ig production is poorly understood. In this study, we have investigated the roles of APRIL (tumor necrosis factor superfamily member [TNFSF] 13) and BAFF
Autor:
Yuji Kashiwakura, Masaaki Hashiguchi, Yumiko Kanno, Tetsuji Kobata, Ayano Kobayashi, Hidefumi Kojima
Publikováno v:
Immunology Letters. 165:1-9
Anatomical containment of commensal bacteria in the intestinal mucosa is promoted by innate lymphoid cells (ILCs). However, the mechanism by which ILCs regulate bacterial localization to specific regions remains unknown. Here we show that Peyer's pat
Autor:
Yumiko Kanno, Yuji Kashiwakura, Tetsuji Kobata, Masaaki Hashiguchi, Hidefumi Kojima, Ayano Kobayashi
Publikováno v:
European Journal of Immunology. 45:876-885
Eosinophils are multifunctional leukocytes involved in allergic reactions as well as adipose tissue regulation. IL-5 is required for eosinophil survival; however, the in vivo mechanisms of eosinophil regulation are not fully understood. A tg mouse mo
Autor:
Ayano Kobayashi, Akira Kurosu, Yuji Kashiwakura, Hidefumi Kojima, Shogo Tokudome, Yumiko Kanno, Tetsuji Kobata, Masaaki Hashiguchi
Publikováno v:
Cytotechnology. 66:373-382
IL-5 plays important roles in eosinophil differentiation, expansion, and recruitment. The regulation of IL-5 seems critical for the treatment of eosinophil-mediated allergic reactions. However, the precise mechanisms for IL-5 regulation remain unknow
Publikováno v:
Journal of Receptors and Signal Transduction. 30:121-132
B-cell-activating factor of the TNF family (BAFF) is a critical factor for B-cell survival and maturation through non-canonical nuclear factor kappaB (NF-kappaB) pathway, a NF-kappaB inducing kinase (NIK)-dependent pathway for the processing of NF-ka