Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yumiko Akamine"'
Autor:
Hayato Yokota, Yumiko Akamine, Mizuki Kobayashi, Takuro Kitabayashi, Misato Horie, Tentaro Endo, Takechiyo Yamada, Masafumi Kikuchi
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Background Naldemedine is an orally available peripherally acting μ-opioid receptor antagonist approved to treat opioid-induced constipation (OIC). It is contraindicated for patients with known or suspected gastrointestinal obstruction to p
Externí odkaz:
https://doaj.org/article/67ae06cdfc84401493f0fa958bd84671
Autor:
Hayato Yokota, Ruriko Asahi, Yumiko Akamine, Mizuki Kobayashi, Hiyu Wakabayashi, Sho Sakamoto, Yuji Okuda, Kazuhiro Sato, Katsutoshi Nakayama, Masafumi Kikuchi
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Background Anamorelin, a drug to treat cancer cachexia, binds to ghrelin receptors and improves body weight and appetite. In clinical trials in Japan, patients experienced a 10.7% frequency of stimulant conduction system depression as a seve
Externí odkaz:
https://doaj.org/article/29a2149f1da5400eae046b40c766a517
Autor:
Hideaki Kagaya, Takenori Niioka, Mitsuru Saito, Takamitsu Inoue, Kazuyuki Numakura, Ryohei Yamamoto, Yumiko Akamine, Tomonori Habuchi, Shigeru Satoh, Masatomo Miura
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 882 (2018)
While tacrolimus and everolimus have common metabolic pathways through CYP3A4/5, tacrolimus is metabolized solely by CYP3A4 in recipients with the CYP3A5*3/*3. The purpose of this study was to evaluate how the area under the blood concentration-time
Externí odkaz:
https://doaj.org/article/a7845f0aadc9464dba06218b4776e5f0
Autor:
Laura Lahtinen, Xavier Ekolle Ndode-Ekane, Filip Barinka, Yumiko Akamine, Mohammed Hossein Esmaeili, Jukka Rantala, Asla Pitkänen
Publikováno v:
Neurobiology of Disease, Vol 37, Iss 3, Pp 692-703 (2010)
Expression of urokinase-type plasminogen activator (uPA) is increased after brain injury, suggesting that, like in cancer tissue, uPA plays roles in brain remodeling. Here we injured brain with intrahippocampal kainic acid (KA) injection in adult Wt
Externí odkaz:
https://doaj.org/article/5bc2ce48f09048fa8d76f0d2f3b00348
Autor:
Laura Lahtinen, Xavier Ekolle Ndode-Ekane, Filip Barinka, Yumiko Akamine, Mohammed Hossein Esmaeili, Jukka Rantala, Asla Pitkänen
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 1, Pp 226- (2011)
Externí odkaz:
https://doaj.org/article/8e26c7e93e4241ccabe461d87a550fa4
Publikováno v:
YAKUGAKU ZASSHI. 143:377-383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c85eec0264104615d89c9c4ff40809
https://doi.org/10.1248/yakushi.22-00182
https://doi.org/10.1248/yakushi.22-00182
Autor:
Kiminori Sugino, Yumiko Akamine, Mitsuji Nagahama, Tomoko Ozeki, Koichi Ito, Maho Kumagai, Masatomo Miura, Akifumi Suzuki
Publikováno v:
Cancer Diagn Progn
Purpose: The purpose of this study was to investigate the relationships among plasma concentrations of lenvatinib, angiopoietin (Ang)-1 and Ang-2, and clinical responses to lenvatinib therapy in Japanese patients with thyroid cancer. Methods: Plasma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c729fe0b6845aef49e39426f832ae065
https://doi.org/10.21873/cdp.10114
https://doi.org/10.21873/cdp.10114
Autor:
Natsuki Fukuda, Yumiko Akamine, Maiko Abumiya, Saori Takahashi, Tomoko Yoshioka, Yoshihiro Kameoka, Naoto Takahashi, Masatomo Miura
Publikováno v:
Cancer Chemotherapy and Pharmacology. 89:609-616
We evaluated the plasma exposure and response relationships of nilotinib for patients with newly diagnosed chronic myeloid leukemia (CML) in real-world practice.For the 26 patients enrolled in this study, at 3, 6, 12, and 24 months after nilotinib ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd579377869c04b3b9a1ee3c5395f43
https://doi.org/10.1007/s00280-022-04419-1
https://doi.org/10.1007/s00280-022-04419-1
Autor:
Yayoi Fukushi, Yumiko Akamine, Maiko Abumiya, Nagi Tozawa, Takaya Yamashita, Miho Nara, Yoshihiro Kameoka, Naoto Takahashi, Masatomo Miura
Publikováno v:
British journal of clinical pharmacologyREFERENCES.
The effects of polymorphisms of ABCB1 and ABCG2 on the dose-adjusted plasma trough concentrations and cerebrospinal fluid (CSF)-to-plasma ratios of ponatinib were evaluated. Blood (C4) and CSF (CSF4) concentrations at 4 h after administration were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29327bfbab241d8577a4c73273b1a47
https://pubmed.ncbi.nlm.nih.gov/36541130
https://pubmed.ncbi.nlm.nih.gov/36541130
Autor:
Jeffery R. Wickens, Serge N. Schiffmann, Alban de Kerchove d'Exaerde, Stefan Pommer, Yumiko Akamine
Publikováno v:
The Journal of Neuroscience
The Journal of neuroscience
The Journal of neuroscience
The principal neurons of the striatum - the spiny projection neurons (SPNs) - make inhibitory synaptic connections with each other via collaterals of their main axon, forming a local lateral inhibition network. Serotonin, acting via the 5-HT1B recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a14c2cd71a2660a8fe978b8b4c58701
http://id.nii.ac.jp/1394/00002417/
http://id.nii.ac.jp/1394/00002417/