Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Yumiko, Sakurai"'
Autor:
Takeshi Matsumoto, Yumiko Sakurai, Noriyuki Tashima, Tomoya Matoba, Akiko Kaneko, Takahiro Fujiki, Yusuke Kusakabe, Emi Nakayama, Ayaka Tanaka, Mayuko Tashima, Naoki Yamamoto, Kensaku Aihara
Publikováno v:
Respirology Case Reports, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract The efficacy and safety of the combination of biologic therapies remain unclear with an ineffective and insufficient single biologic for managing asthma. Herein, we report two cases using dual biologics for severe asthma and atopic dermatiti
Externí odkaz:
https://doaj.org/article/654cc15de8cf45e4866ffa78d732fa48
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Currently, point-of-care assays for human platelet function and coagulation are used to assess bleeding risks and drug testing, but they lack intact endothelium, a critical component of the human vascular system. Within these assays, the assessment o
Externí odkaz:
https://doaj.org/article/4631ad375c8b4edeb8233cf3e226b4b2
Autor:
Samuel Druzak, Elizabeth Iffrig, Blaine R. Roberts, Tiantian Zhang, Kirby S. Fibben, Yumiko Sakurai, Hans P. Verkerke, Christina A. Rostad, Ann Chahroudi, Frank Schneider, Andrew Kam Ho Wong, Anne M. Roberts, Joshua D. Chandler, Susan O. Kim, Mario Mosunjac, Marina Mosunjac, Rachel Geller, Igor Albizua, Sean R. Stowell, Connie M. Arthur, Evan J. Anderson, Anna A. Ivanova, Jun Ahn, Xueyun Liu, Kristal Maner-Smith, Thomas Bowen, Mirko Paiardini, Steve E. Bosinger, John D. Roback, Deanna A. Kulpa, Guido Silvestri, Wilbur A. Lam, Eric A. Ortlund, Cheryl L. Maier
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
In this work, authors take a multiomics and microfluidics-based approach to elucidate the mechanism of endothelial damage in critical illness associated with SARS-CoV-2.
Externí odkaz:
https://doaj.org/article/f453c7377ff248be8d16d63d8c87445a
Autor:
Oluwamayokun Oshinowo, Tamara Lambert, Yumiko Sakurai, Renee Copeland, Caroline E. Hansen, Wilbur A. Lam, David R. Myers
Publikováno v:
Platelets, Vol 31, Iss 5, Pp 570-579 (2020)
As the anucleate cells responsible for hemostasis and thrombosis, platelets are exposed to a myriad of biophysical and biochemical stimuli within vasculature and heterogeneous blood clots. Highly controlled, reductionist in vitro imaging studies have
Externí odkaz:
https://doaj.org/article/d95ff8e47642476d8dd1fb359f95463b
Autor:
Takeshi Matsumoto, Yumiko Sakurai, Takahiro Fujiki, Yusuke Kusakabe, Emi Nakayama, Ayaka Tanaka, Naoki Yamamoto, Kensaku Aihara, Shinpachi Yamaoka, Michiaki Mishima
Publikováno v:
Internal Medicine. 62:1219-1222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f3df5e938e7308efea85ecc9ec57878
https://doi.org/10.2169/internalmedicine.1169-22
https://doi.org/10.2169/internalmedicine.1169-22
Autor:
Keisuke Jimbo, Toshiaki Okuno, Ryuichi Ohgaki, Kou Nishikubo, Yuri Kitamura, Yumiko Sakurai, Lili Quan, Hiromichi Shoji, Yoshikatsu Kanai, Toshiaki Shimizu, Takehiko Yokomizo
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247691 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0241869.].
Externí odkaz:
https://doaj.org/article/7ecbdf20d5d34a97a5b6a615b1007e59
Autor:
Keisuke Jimbo, Toshiaki Okuno, Ryuichi Ohgaki, Kou Nishikubo, Yuri Kitamura, Yumiko Sakurai, Lili Quan, Hiromichi Shoji, Yoshikatsu Kanai, Toshiaki Shimizu, Takehiko Yokomizo
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241869 (2020)
Chronic enteropathy associated with SLCO2A1 gene (CEAS) is caused by loss-of-function mutations in SLCO2A1, which encodes a prostaglandin (PG) transporter. In this study, we report a sibling case of CEAS with a novel pathogenic variant of the SLCO2A1
Externí odkaz:
https://doaj.org/article/33c367819fab4eb68e2c495376f902ea
A microengineered vascularized bleeding model that integrates the principal components of hemostasis
Autor:
Yumiko Sakurai, Elaissa T. Hardy, Byungwook Ahn, Reginald Tran, Meredith E. Fay, Jordan C. Ciciliano, Robert G. Mannino, David R. Myers, Yongzhi Qiu, Marcus A. Carden, W. Hunter Baldwin, Shannon L. Meeks, Gary E. Gilbert, Shawn M. Jobe, Wilbur A. Lam
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Hemostasis is a complex ensemble of events, but current bleeding assays only analyze single components like coagulation or platelet function. Here the authors present a comprehensive vascularized microfluidic mechanical injury bleeding model that add
Externí odkaz:
https://doaj.org/article/27d88574773748ba80530b1b1ef77b32
Autor:
Yongzhi Qiu, Sheng Tong, Linlin Zhang, Yumiko Sakurai, David R. Myers, Lin Hong, Wilbur A. Lam, Gang Bao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The transportation of large molecules through the vascular endothelium presents a major challenge forin vivodrug delivery. Here, the authors demonstrate the potential of using external magnetic fields and magnetic nanoparticles to enhance the local e
Externí odkaz:
https://doaj.org/article/e46df2218ab044b5b981f4c1ffa07ffd
Autor:
Saeko Hirai, Mitsuyoshi Suzuki, Yumiko Sakurai, Satoshi Nakano, Kei Minowa, Hidetake Eguchi, Yasushi Okazaki, Toshiaki Shimizu
Publikováno v:
Journal of pediatric gastroenterology and nutrition.
Recently, a genetic risk for chronic pancreatitis (CP) was found to be conferred by pathogenic variants in the transient receptor potential cation channel, subfamily V, member 6 (TRPV6). Interestingly, 20-57% of patients with functionally defective T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e40011540379a302be2af9d5ccd8b54
https://pubmed.ncbi.nlm.nih.gov/36599151
https://pubmed.ncbi.nlm.nih.gov/36599151