Zobrazeno 1 - 10
of 384
pro vyhledávání: '"Yumiko, Saga"'
Autor:
Masae Itamochi, Shunsuke Yazawa, Yumiko Saga, Takahisa Shimada, Kosuke Tamura, Emi Maenishi, Junko Isobe, Hitoshi Sasajima, Chikako Kawashiri, Hideki Tani, Kazunori Oishi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Residents in nursing homes face heightened COVID-19 risks. We aimed to assess the adverse events (AEs) rates and antibody responses after the first to the fifth dose of COVID-19 mRNA vaccination in a nursing home cohort. Ninety-five SARS-CoV
Externí odkaz:
https://doaj.org/article/85ab8979fe53416193d0cfd710d125b1
Autor:
Wataru Masuda, Tomoko Yamakawa, Rieko Ajima, Katsuya Miyake, Toshifumi Umemiya, Kazuhiko Azuma, Jun-ichi Tamaru, Makoto Kiso, Puspa Das, Yumiko Saga, Kenji Matsuno, Motoo Kitagawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Notch signaling is an evolutionarily conserved mechanism required for numerous types of cell fate decisions in metazoans. It mediates short-range communication between cells with receptors and ligands, both of which are expressed on the cell
Externí odkaz:
https://doaj.org/article/db8e41c628a4412e85d3d2da141b5a7e
Autor:
Emiko Yamazaki, Shunsuke Yazawa, Takahisa Shimada, Kosuke Tamura, Yumiko Saga, Masae Itamochi, Noriko Inasaki, Sumiyo Hasegawa, Yoshitomo Morinaga, Kazunori Oishi, Hideki Tani
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract SARS-CoV-2 enters host cells through the angiotensin converting enzyme 2 (ACE2) receptor and/or transmembrane protease, serine 2 (TMPRSS2). In this study, we investigated whether proteases increased SARS-CoV-2 infectivity using pseudotyped v
Externí odkaz:
https://doaj.org/article/cd8f4ad4923142cfb9b5de9d201364b6
Autor:
Shunsuke Yazawa, Emiko Yamazaki, Yumiko Saga, Masae Itamochi, Noriko Inasaki, Takahisa Shimada, Kazunori Oishi, Hideki Tani
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract It has been revealed that SARS-CoV-2 can be efficiently isolated from clinical specimens such as nasal/nasopharyngeal swabs or saliva in cultured cells. In this study, we examined the efficiency of viral isolation including SARS-CoV-2 mutant
Externí odkaz:
https://doaj.org/article/5ebc14b5f99a4624aca941abee67d05a
Autor:
Hiroshi Yamada, So-Ichiro Sasaki, Hideki Tani, Mayu Somekawa, Hitoshi Kawasuji, Yumiko Saga, Yoshihiro Yoshida, Yoshihiro Yamamoto, Yoshihiro Hayakawa, Yoshitomo Morinaga
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a biosafety level (BSL)-3 pathogen; therefore, its research environment is limited. Pseudotyped viruses that mimic the infection of SARS-CoV-2 have been widely used for in vitro
Externí odkaz:
https://doaj.org/article/30bb960f7004482ebb6918cc9b1b8e70
Autor:
Yumiko Saga, Toshikazu Yoshida, Rieko Yoshida, Shunsuke Yazawa, Takahisa Shimada, Noriko Inasaki, Masae Itamochi, Emiko Yamazaki, Kazunori Oishi, Hideki Tani
Publikováno v:
Viruses, Vol 15, Iss 11, p 2228 (2023)
Severe fever with thrombocytopenia syndrome (SFTS) is a tick-borne infection caused by the SFTS virus (SFTSV), with a high fatality rate of approximately 30% in humans. In recent years, cases of contact infection with SFTSV via bodily fluids of infec
Externí odkaz:
https://doaj.org/article/b0a2d65067b641dd8ad2848a67886d00
Autor:
Tatsuhiko Ozawa, Hideki Tani, Yuki Anraku, Shunsuke Kita, Emiko Igarashi, Yumiko Saga, Noriko Inasaki, Hitoshi Kawasuji, Hiroshi Yamada, so-Ichiro Sasaki, Mayu Somekawa, Jiei Sasaki, Yoshihiro Hayakawa, Yoshihiro Yamamoto, Yoshitomo Morinaga, Nobuyuki Kurosawa, Masaharu Isobe, Hideo Fukuhara, Katsumi Maenaka, Takao Hashiguchi, Hiroyuki Kishi, Isao Kitajima, Shigeru Saito, Hideki Niimi
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
Many potent neutralizing SARS-CoV-2 antibodies have been developed and used for therapies. However, the effectiveness of many antibodies has been reduced against recently emerging SARS-CoV-2 variants, especially the Omicron variant. We identified a h
Externí odkaz:
https://doaj.org/article/8f1dc584acce4456861e83257e43534d
Publikováno v:
PLoS Genetics, Vol 18, Iss 10 (2022)
The evolutionarily conserved RNA helicase DDX6 is a central player in post-transcriptional regulation, but its role during embryogenesis remains elusive. We here show that DDX6 enables proper cell lineage specification from pluripotent cells by analy
Externí odkaz:
https://doaj.org/article/0ac4b33ece0d41ee87ae8a14e6b4aaee
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110894- (2022)
Summary: The germ-cell-specific RNA-binding protein (RBP) NANOS2 plays a pivotal role in male gonocyte differentiation and spermatogonial stem cell maintenance. Although NANOS2 interacts with the CNOT deadenylation complex and Dead end 1 (DND1) to re
Externí odkaz:
https://doaj.org/article/d5b9c1cb661f4008a5afa056d2a72e67
Publikováno v:
Biology Open, Vol 11, Iss 4 (2022)
In the mouse testis, sperm originate from spermatogonial stem cells (SSCs). SSCs give rise to spermatogonial progenitors, which expand their population until entering the differentiation process that is precisely regulated by a fixed time-scaled prog
Externí odkaz:
https://doaj.org/article/46b74000a2e948a6bdf1b75a30a74b8c