Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Yumiko, Motoi"'
Autor:
Haruka Takeshige-Amano, Genko Oyama, Mayuko Ogawa, Keiko Fusegi, Taiki Kambe, Kenta Shiina, Shin-ichi Ueno, Ayami Okuzumi, Taku Hatano, Yumiko Motoi, Ito Kawakami, Maya Ando, Sachiko Nakayama, Yoshinori Ishida, Shun Maei, Xiangxun Lu, Tomohisa Kobayashi, Rina Wooden, Susumu Ota, Ken Morito, Yoshitaka Ito, Yoshihiro Nakajima, Asako Yoritaka, Tadafumi Kato, Nobutaka Hattori
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In super-aged societies, dementia has become a critical issue, underscoring the urgent need for tools to assess cognitive status effectively in various sectors, including financial and business settings. Facial and speech features have been
Externí odkaz:
https://doaj.org/article/60fa9b4f8a394205a2e5c2fd1a9afd4c
Autor:
Kazuo Yamashiro, Kaito Takabayashi, Koji Kamagata, Yuichiro Nishimoto, Yuka Togashi, Yohsuke Yamauchi, Kotaro Ogaki, Yuanzhe Li, Taku Hatano, Yumiko Motoi, Michimasa Suzuki, Koichi Miyakawa, Dai Ishikawa, Shigeki Aoki, Takao Urabe, Nobutaka Hattori
Publikováno v:
Neurobiology of Disease, Vol 193, Iss , Pp 106464- (2024)
Neuroinflammation contributes to the pathology and progression of Alzheimer's disease (AD), and it can be observed even with mild cognitive impairment (MCI), a prodromal phase of AD. Free water (FW) imaging estimates the extracellular water content a
Externí odkaz:
https://doaj.org/article/1846f49fbc784cb1bcd8a3d751f56d02
Autor:
Ahmed Imtiaz, Shotaro Shimonaka, Mohammad Nasir Uddin, Montasir Elahi, Koichi Ishiguro, Masato Hasegawa, Nobutaka Hattori, Yumiko Motoi
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The efficacy of current treatments is still insufficient for Alzheimer’s disease (AD), the most common cause of Dementia. Out of the two pathological hallmarks of AD amyloid-β plaques and neurofibrillary tangles, comprising of tau protein, tau pat
Externí odkaz:
https://doaj.org/article/160579159a284f1596db2265a64b6963
Autor:
Yuki Someya, Yoshifumi Tamura, Hideyoshi Kaga, Daisuke Sugimoto, Satoshi Kadowaki, Ruriko Suzuki, Shigeki Aoki, Nobutaka Hattori, Yumiko Motoi, Kazunori Shimada, Hiroyuki Daida, Muneaki Ishijima, Kazuo Kaneko, Shuko Nojiri, Ryuzo Kawamori, Hirotaka Watada
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Insulin resistance and muscle weakness are risk factors for silent lacunar infarcts (SLI), but it is unclear whether they are still independent risk factors when adjusted for each other. In addition, the effect of their combination on SLI is
Externí odkaz:
https://doaj.org/article/5658d64461d34cb08bb3e41d3d1d40dc
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Externí odkaz:
https://doaj.org/article/fa6ce20e3b4440599fd4633859f946a3
Autor:
Imtiaz, Ahmed, Shotaro Shimonaka, Uddin, Mohammad Nasir, Elahi, Montasir, Koichi Ishiguro, Masato Hasegawa, Nobutaka Hattori, Yumiko Motoi
Publikováno v:
Frontiers in Aging Neuroscience; 2024, p1-15, 15p
Autor:
Hiroshi Matsuda, Kyoji Okita, Yumiko Motoi, Toshiki Mizuno, Manabu Ikeda, Nobuo Sanjo, Koji Murakami, Taiki Kambe, Toshiki Takayama, Kei Yamada, Takashi Suehiro, Keiko Matsunaga, Takanori Yokota, Ukihide Tateishi, Yoko Shigemoto, Yukio Kimura, Emiko Chiba, Takahiro Kawashima, Yui Tomo, Hisateru Tachimori, Yuichi Kimura, Noriko Sato
Publikováno v:
Annals of Nuclear Medicine. 36:1039-1049
Objective Amyloid positron emission tomography (PET) can reliably detect senile plaques and fluorinated ligands are approved for clinical use. However, the clinical impact of amyloid PET imaging is still under investigation. The aim of this study was
Autor:
Kazuo Kaneko, Yuki Someya, Yoshifumi Tamura, Hideyoshi Kaga, Shuko Nojiri, Kazunori Shimada, Hiroyuki Daida, Muneaki Ishijima, Shigeki Aoki, Takashi Miida, Satoshi Hirayama, Seiki Konishi, Nobutaka Hattori, Yumiko Motoi, Hisashi Naito, Ryuzo Kawamori, Hirotaka Watada
Publikováno v:
BMJ Open, Vol 9, Iss 9 (2019)
Purpose The proportion of elderly individuals (age ≥65 years) in Japan reached 27.7% in 2017, the highest in the world. A serious social problem in a super-aged society is the rise in the number of elderly people who need long-term care (LTC), whic
Externí odkaz:
https://doaj.org/article/1b3a92afe9c2406aa9a2b7724c1b4099
Autor:
Hiroyo Yoshino, Yuanzhe Li, Kenya Nishioka, Kensuke Daida, Arisa Hayashida, Yuta Ishiguro, Daisuke Yamada, Nana Izawa, Katsunori Nishi, Noriko Nishikawa, Genko Oyama, Taku Hatano, Shinichiro Nakamura, Asako Yoritaka, Yumiko Motoi, Manabu Funayama, Nobutaka Hattori
Publikováno v:
Neurobiology of Aging. 114:117-128
To investigate the prevalence and genotype-phenotype correlations of parkin RBR E3 ubiquitin protein ligase (PRKN) variants in Parkinson's disease (PD), we first included 2,527 patients with PD. Through the defined selection, we enrolled 2,322 patien
Autor:
Atsushi Hori, Tomohiko Ai, Miwa Isshiki, Yumiko Motoi, Kouji Yano, Yoko Tabe, Nobutaka Hattori, Takashi Miida
Publikováno v:
Geriatrics, Vol 6, Iss 1, p 14 (2021)
Dementia has an enormous impact on medical and financial resources in aging societies like Japan. Diagnosis of dementia can be made by physical and mental examinations, imaging tests, and findings of high abnormal proteins in cerebrospinal fluids. In
Externí odkaz:
https://doaj.org/article/2f9a6f21a5e745c9ab807b01ca92f954