Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Yumi Kangawa"'
Autor:
Yoko Kagawa, Licht Miyamoto, Yasumasa Ikeda, Yumi Kangawa, Yuri Morimoto, Toshiaki Tamaki, Shuichi Hamano, Koichiro Tsuchiya, Yuya Horinouchi, Wenting Xu, Chika Fukue, Katsunori Tsuda
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:555-563
Artemisinin was discovered in 1971 as a constituent of the wormwood genus plant (Artemisia annua). This plant has been used as an herbal medicine to treat malaria since ancient times. The compound artemisinin has a sesquiterpene lactone bearing a per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259f7666af89f38aa28d42bb362800ba
https://doi.org/10.1248/bpb.b17-00855
https://doi.org/10.1248/bpb.b17-00855
Autor:
Shim-mo Hayashi, Hajime Abe, Makoto Shibutani, Toshinori Yoshida, Tohru Kihara, Michi Nakamura, Yumi Kangawa, Yoshiki Seto, Taishi Miyashita
Publikováno v:
Experimental and Toxicologic Pathology. 69:179-186
Developing effective treatments and preventing inflammatory bowel disease (IBD) are urgent challenges in improving patients' health. It has been suggested that platelet activation and reactive oxidative species generation are involved in the pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2031f98db60f91b098628fe88bac8dd1
https://doi.org/10.1016/j.etp.2016.12.004
https://doi.org/10.1016/j.etp.2016.12.004
Autor:
Yumi Kangawa, Satoko Enya, Masatoshi Shibata, Masayoshi Otake, Akihisa Kangawa, Toshinori Yoshida
Publikováno v:
Toxicologic Pathology. 44:974-986
The microminipig has considerable potential as an animal model to evaluate general toxicity; however, there are few studies on the male reproductive system, particularly regarding spermatogenesis. The objectives of the present study were to clarify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5654216f967ece6f72674e3a08a37705
https://doi.org/10.1177/0192623316654586
https://doi.org/10.1177/0192623316654586
Autor:
Yui Fujita, Toshio Doi, Taichi Murakami, Yumi Kangawa, Kou Ichi Jishage, Otoya Ueda, Naoshi Fukushima, Seiji Kishi, Hideharu Abe, Yumiko Saga, Kojiro Nagai, Tatsuya Tominaga, Yashpal S. Kanwar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Podocyte injury has been proposed to play an important role in diabetic nephropathy; however, its pathological mechanism remains unclear. We have shown that bone morphogenetic protein 4 (BMP4) signaling leads to the glomerular changes characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb73c9f03e71688b83ff238bb06c86d
https://pubmed.ncbi.nlm.nih.gov/30158674
https://pubmed.ncbi.nlm.nih.gov/30158674
Autor:
Yumi Kangawa, Makoto Shibutani, Toshinori Yoshida, Sayaka Mizukami, Masayuki Kimura, Nobuhiko Onda, Yoh Kikuchihara
Publikováno v:
Experimental and Toxicologic Pathology. 67:349-353
Azoxymethane (AOM) is a potent carcinogen used for induction of colon tumors in rats and mice. It is also known that AOM treatment induces small bowel tumors in addition to colorectal tumors in rats. The present study examined the histogenesis of AOM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b400d298ba06105e1502140ef2fbab16
https://doi.org/10.1016/j.etp.2015.03.002
https://doi.org/10.1016/j.etp.2015.03.002
Autor:
Kiyoshi Maruyama, Yumi Kangawa, Shim-mo Hayashi, Toshinori Yoshida, Makoto Shibutani, Yutaka Yonezawa
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 69(8)
In the gastrointestinal tract, the immediate healing response to mucosal damage is critical to sustain mucosal homeostasis. The migration of surrounding epithelial cells to cover the denuded area without proliferation is termed restitution, followed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8b594959805067d2113694497240bb
https://pubmed.ncbi.nlm.nih.gov/28535907
https://pubmed.ncbi.nlm.nih.gov/28535907
Autor:
Naomi Koyama, Akira Kataoka, Shim-mo Hayashi, Makoto Shibutani, Toshinori Yoshida, Tomoka Ohsumi, Yumi Kangawa, Takeshi Tanaka
Publikováno v:
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 69(7)
We demonstrate the expression patterns of A-kinase anchor protein 13 (AKAP13), a scaffold protein that acts upstream of Rho signaling, and Rho-associated coiled-coil containing protein kinase (ROCK) 1/2 in mouse colorectal cancer and during the heali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea89d8a798e93c3697ede39e83fac1d3
https://pubmed.ncbi.nlm.nih.gov/28434818
https://pubmed.ncbi.nlm.nih.gov/28434818
Autor:
Atsushi Iwata, Toshiyuki Shibanushi, Radhakrishnan Pillai, Yoshiyuki Tatsumi, Fumie Inui, Maria Nagashima, Yumi Kangawa, Yayoi Nishiyama, William J. Jo Siu
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:2405-2409
The mechanism of action of efinaconazole, a new triazole antifungal, was investigated with Trichophyton mentagrophytes and Candida albicans . Efinaconazole dose-dependently decreased ergosterol production and accumulated 4,4-dimethylsterols and 4α-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8732f40d9ec5030b32cdd9325fd9317b
https://doi.org/10.1128/aac.02063-12
https://doi.org/10.1128/aac.02063-12
Autor:
Shim-mo Hayashi, Tohru Kihara, Kiyoshi Maruyama, Makoto Shibutani, Minako Okamoto, Yoshitaka Hippo, Michi Nakamura, Masako Ochiai, Toshinori Yoshida, Yumi Kangawa
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 100
We previously reported the anti-inflammatory effects of cilostazol, a selective inhibitor of phosphodiesterase 3, and two antioxidants, enzymatically modified isoquercitrin and α-lipoic acid in a dextran sodium sulphate-induced colitis mouse model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331b5ec51b61d74b6777a2993f957cb0
https://pubmed.ncbi.nlm.nih.gov/27989839
https://pubmed.ncbi.nlm.nih.gov/27989839
Autor:
Yumi Kangawa, Yasuko Hasegawa-Baba, Makoto Shibutani, Toshinori Yoshida, Sayaka Mizukami, Takeshi Tanaka, Yousuke Watanabe
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 65
To elucidate the developmental exposure effects of ochratoxin A (OTA) on postnatal hippocampal neurogenesis, pregnant SD rats were provided a diet containing 0, 0.12, 0.6, or 3.0ppm OTA from gestation day 6 to day 21 on weaning after delivery. Offspr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33dbfaaffecfbebd5058a5623ff2d22
https://pubmed.ncbi.nlm.nih.gov/27346841
https://pubmed.ncbi.nlm.nih.gov/27346841