Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Yuma Umezaki"'
Autor:
Takatsugu Murata, Hisazumi Tsutsui, Takumi Yoshida, Hirokazu Kubota, Shintaro Hiraishi, Hiyo Natsukawa, Yuki Suzuki, Daiki Hiraga, Takahiro Mori, Yutaro Maekawa, Satoru Tateyama, Kiyotaka Toyoyama, Keiichi Ito, Kyohei Suzuki, Keita Yonekura, Natsumi Shibata, Teruyuki Sato, Yasutaka Tasaki, Takehiko Inohana, Atsuhiro Takano, Naoki Egashira, Masaki Honda, Yuma Umezaki, Isamu Shiina
Publikováno v:
ACS Omega, Vol 8, Iss 33, Pp 30789-30789 (2023)
Externí odkaz:
https://doaj.org/article/a4ff92c99e87498c92ccaec2ecbb52e7
Autor:
Takatsugu Murata, Hisazumi Tsutsui, Takumi Yoshida, Hirokazu Kubota, Shintaro Hiraishi, Hiyo Natsukawa, Yuki Suzuki, Daiki Hiraga, Takahiro Mori, Yutaro Maekawa, Satoru Tateyama, Kiyotaka Toyoyama, Keiichi Ito, Kyohei Suzuki, Keita Yonekura, Natsumi Shibata, Teruyuki Sato, Yasutaka Tasaki, Takehiko Inohana, Atsuhiro Takano, Naoki Egashira, Masaki Honda, Yuma Umezaki, Isamu Shiina
The first total synthesis of (+)-tanzawaic acid B, a natural polyketide bearing a pentadienoic ester and octalin moiety, has been accomplished. The synthetic improvement from previous synthetic conditions facilitated our gram-scale synthesis of the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4249a5ab572487b512014065a57b3520
https://doi.org/10.26434/chemrxiv-2022-p8hxs-v3
https://doi.org/10.26434/chemrxiv-2022-p8hxs-v3
Publikováno v:
Synthesis. 50:1301-1306
In this paper, we report the first total synthesis of (+)-coprophilin, an anticoccidial agent, by constructing the chiral linear precursor via a Mukaiyama–Evans aldol reaction and a stereoselective intramolecular Diels–Alder reaction. The propose
Publikováno v:
Synthesis; 2018, Vol. 50 Issue 6, p1301-1306, 6p
Autor:
Seiichi Hitomi, Ryo Suzuki, Tatsuhiko Ikeda, Isamu Shiina, Yuma Umezaki, Hiroki Fukui, Keisuke Tsuji
Publikováno v:
Tetrahedron Letters. 49:6514-6517
The stereoselective total syntheses of botcinic acid, botcinic acid methyl ester, 3-O-acetylbotcinic acid methyl ester, botcineric acid, and botcinin E were achieved. The structures of these compounds have been unequivocally determined through their
Publikováno v:
Journal of medicinal chemistry. 56(1)
An effective method for the total synthesis of 1 (AMF-26), a potentially promising new anticancer drug that disrupts the Golgi system by inhibiting the ADP-ribosylation factor 1 (Arf1) activation, has been developed for the first time. The constructi
Publikováno v:
The Journal of organic chemistry. 77(11)
Various β-lactones were prepared from β-hydroxycarboxylic acids by intramolecular dehydration condensation using MNBA, an effective coupling reagent, along with a nucleophilic catalyst. The transition state that provides the desired 4-membered ring
Publikováno v:
ChemInform. 40
The stereoselective total syntheses of botcinins A (1) and B (2), and homobotcinin E (4), a homologue of botcinin E (3), have been achieved starting from a polyoxygenated tetrahydropyran intermediate 15 via formation of botcinic acid (12) and botcine
Publikováno v:
HETEROCYCLES. 79:403
The stereoselective total syntheses of botcinins A (1) and B (2), and homobotcinin E (4), a homologue of botcinin E (3), have been achieved starting from a polyoxygenated tetrahydropyran intermediate 15 via formation of botcinic acid (12) and botcine
Autor:
Setsu G; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan. Electronic address: setsu.genzui.dm@daiichisankyo.co.jp., Goto M; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Ito K; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Taira T; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Miyamoto M; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Watanabe T; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Taniguchi T; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Umezaki Y; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Nakazawa Y; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Uesugi S; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Mori K; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Horiuchi T; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Obuchi W; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan., Minami M; Daiichi Sankyo RD Novare Co., Ltd., Tokyo, 134-8630, Japan., Shimada T; Daiichi Sankyo RD Novare Co., Ltd., Tokyo, 134-8630, Japan., Wada C; Daiichi Sankyo RD Novare Co., Ltd., Tokyo, 134-8630, Japan., Yoshida T; Daiichi Sankyo RD Novare Co., Ltd., Tokyo, 134-8630, Japan., Higuchi S; Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan.
Publikováno v:
European journal of pharmacology [Eur J Pharmacol] 2023 Dec 15; Vol. 961, pp. 176184. Date of Electronic Publication: 2023 Nov 08.