Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Yuma Terasawa"'
Autor:
Saeid Malek Zadeh, Mei-Hua Chen, Zhe-Chong Wang, Elahe K. Astani, I-Wen Lo, Kuan-Hung Lin, Ning-Shian Hsu, Kamal Adhikari, Syue-Yi Lyu, Hsin-Ying Tsai, Yuma Terasawa, Miyuki Yabe, Kazuki Yamamoto, Satoshi Ichikawa, Tsung-Lin Li
Publikováno v:
Communications Chemistry, Vol 5, Iss 1, Pp 1-16 (2022)
Caprazamycin is a nucleoside antibiotic that can interrupt bacterial peptidoglycan biosynthesis, but the biosynthesis of caprazamycin is not fully understood yet. Here, the authors characterize five key enzymes from caprazamycin/muraymycin gene clust
Externí odkaz:
https://doaj.org/article/22746e753b0343b29bcee91137ebd8a5
Autor:
Ellene H. Mashalidis, Benjamin Kaeser, Yuma Terasawa, Akira Katsuyama, Do-Yeon Kwon, Kiyoun Lee, Jiyong Hong, Satoshi Ichikawa, Seok-Yong Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Phospho-MurNAc-pentapeptide translocase (MraY) is a bacterial integral membrane enzyme that is essential for peptidoglycan biosynthesis. Here the authors present the crystal structures of MraY from Aquifex aeolicus bound to caprazamycin, capuramycin
Externí odkaz:
https://doaj.org/article/e0558f6d0eab41fcbb345629cf908792
Autor:
Akira Katsuyama, Yuma Terasawa, Shin-ichi Yokota, Yukari Fukushima, Fumika Yakushiji, Chie Nakajima, Kazuki Yamamoto, Toyotaka Sato, Takanori Matsumaru, Chisato Sataka, Yasuhiko Suzuki, Satoshi Ichikawa
Publikováno v:
Journal of Medicinal Chemistry. 63:9803-9827
The synthesis and biological evaluation of analogues of uridylpeptide antibiotics were described, and the molecular interaction between the 3'-hydroxy analogue of mureidomycin A (3'-hydroxymureidomycin A) and its target enzyme, phospho-MurNAc-pentape