Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Yuma Horii"'
Autor:
Yuma Horii, Shoichi Matsuda, Chikashi Toyota, Takumi Morinaga, Takeo Nakaya, Soken Tsuchiya, Masaki Ohmuraya, Takanori Hironaka, Ryo Yoshiki, Kotaro Kasai, Yuto Yamauchi, Noburo Takizawa, Akiomi Nagasaka, Akira Tanaka, Hidetaka Kosako, Michio Nakaya
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Heart fibrosis involves a feedback loop where stiffening increases fibrosis-related gene expression in myofibroblasts. Here authors reveal the mechanosensitive nuclear translocation of VGLL3, where it phase separates and promotes collagen production,
Externí odkaz:
https://doaj.org/article/3d91cd5901fb4a358a83f06efa607833
Autor:
Akiomi Nagasaka, Chihiro Mogi, Hiroki Ono, Toshihide Nishi, Yuma Horii, Yuki Ohba, Koichi Sato, Michio Nakaya, Fumikazu Okajima, Hitoshi Kurose
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Myocardial infarction (MI) is an ischaemic heart condition caused by the occlusion of coronary arteries. Following MI, lactic acid from anaerobic glycolysis increases and infiltrating immune cells produce severe inflammation, which leads to
Externí odkaz:
https://doaj.org/article/79bdd7ecb0b44afb8eab5d5cabbfc604
Publikováno v:
Bio-Protocol, Vol 7, Iss 18 (2017)
In myocardial infarction (MI), a plenty of cardiomyocytes undergo necrosis and necroptosis due to the lack of oxygen and nutrients. The dead cardiomyocytes are promptly engulfed by phagocytes. When the dead cells are not engulfed, the noxious content
Externí odkaz:
https://doaj.org/article/c46157ad3f704121a3a0f730547f3e54
Publikováno v:
Bio-Protocol, Vol 7, Iss 18 (2017)
In myocardial infarction (MI), a number of cardiomyocytes undergo apoptosis. These apoptotic cardiomyocytes are promptly engulfed by phagocytes. If the dead cells are not engulfed, their noxious contents are released outside, resulting in induction o
Externí odkaz:
https://doaj.org/article/c70766eaf21c46cba2a9a7ff90d0151c
Autor:
Akiomi Nagasaka, Tomoyuki Ueno, Michio Nakaya, Noburo Takizawa, Kyosuke Mae, Takanori Hironaka, Yuma Horii
Publikováno v:
Biochemical and Biophysical Research Communications. 561:180-186
Fibrosis is a condition characterized by the overproduction of extracellular matrix (ECM) components (e.g., collagen) in the myofibroblasts, causing tissue hardening and eventual organ dysfunction. Currently, the molecular mechanisms that regulate EC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e63355dab8529581c17d5720cf036e
https://doi.org/10.1016/j.bbrc.2021.05.035
https://doi.org/10.1016/j.bbrc.2021.05.035
Publikováno v:
Journal of Biological Chemistry. 299:102934
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f33501dab93847069a39a7254667cff
https://doi.org/10.1016/j.jbc.2023.102934
https://doi.org/10.1016/j.jbc.2023.102934
Autor:
Tomoyuki Ueno, Michio Nakaya, Kyosuke Mae, Takanori Hironaka, Yuma Horii, Kotaro Kasai, Akiomi Nagasaka
Publikováno v:
BPB Reports. 4:85-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41120bf7fe56c6a3febece3f848309eb
https://doi.org/10.1248/bpbreports.4.3_85
https://doi.org/10.1248/bpbreports.4.3_85
Autor:
Yuma Horii, Takeo Nakaya, Toshiaki Okuno, Tomoaki Koga, Yuki Sugiura, Akiomi Nagasaka, Hiroaki Nishihara, Hiroki Ohara, Kenji Watari, Hitoshi Kurose, Takehiko Yokomizo, Michio Nakaya, Akira Tanaka
Publikováno v:
The FASEB Journal. 34:8749-8763
Leukotriene B4 receptor 1 (BLT1), a high-affinity G-protein-coupled receptor for leukotriene B4 (LTB4 ), is expressed on various inflammatory cells and plays critical roles in several inflammatory diseases. In myocardial infarction (MI), various infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c42ef864316b3e4914265ff12a7f76c
https://doi.org/10.1096/fj.202000041r
https://doi.org/10.1096/fj.202000041r
Autor:
Michio Nakaya, Kyosuke Mae, Chikashi Yoshimura, Hitoshi Kurose, Tomoyuki Ueno, Yuma Horii, Akiomi Nagasaka, Takumi Morinaga, Takanori Hironaka
Publikováno v:
Biochemical and biophysical research communications. 529(2)
Fibrosis is attributed to excess deposition of extracellular matrix (ECM) proteins including collagen and is associated with various organ dysfunction. This excessive ECM is produced by myofibroblasts, which are differentiated from various cells by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c7d1f1b9b27af0c2bf84f72fc6e252
https://pubmed.ncbi.nlm.nih.gov/32703415
https://pubmed.ncbi.nlm.nih.gov/32703415
Autor:
Yuma, Horii, Michio, Nakaya, Hiroki, Ohara, Hiroaki, Nishihara, Kenji, Watari, Akiomi, Nagasaka, Takeo, Nakaya, Yuki, Sugiura, Toshiaki, Okuno, Tomoaki, Koga, Akira, Tanaka, Takehiko, Yokomizo, Hitoshi, Kurose
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
Leukotriene B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bd1ac586369310de9633cd5b09f71c1
https://pubmed.ncbi.nlm.nih.gov/32385915
https://pubmed.ncbi.nlm.nih.gov/32385915