Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yuma Handa"'
Autor:
Hironori Saito, Yuma Handa, Mingming Chen, Tilman Schneider-Poetsch, Yuichi Shichino, Mari Takahashi, Daniel Romo, Minoru Yoshida, Alois Fürstner, Takuhiro Ito, Kaori Fukuzawa, Shintaro Iwasaki
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Small-molecule compounds that elicit mRNA-selective translation repression have attracted interest due to their potential for expansion of druggable space. However, only a limited number of examples have been reported to date. Here, we show
Externí odkaz:
https://doaj.org/article/422c8ed25eeb44029659f56f873aa1ec
Autor:
Haruya Yagi, Takumi Tomono, Yuma Handa, Natsuki Saito, Masami Ukawa, Kohei Miyata, Koichi Shigeno, Shinji Sakuma
Publikováno v:
Molecular Pharmaceutics. 20:303-313
We have been investigating the potential of cell-penetrating peptides anchored to polymeric platforms as a novel absorption enhancer which delivers biologics into systemic circulation via mucosal routes. Our previous mouse experiments demonstrated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df03d6d05feebecb362834e16beb0aa
https://doi.org/10.1021/acs.molpharmaceut.2c00657
https://doi.org/10.1021/acs.molpharmaceut.2c00657
Autor:
Yoshio Okiyama, Koji Okuwaki, Kaori Fukuzawa, Yuma Handa, Shigenori Tanaka, Ryo Hatada, Yuto Komeiji, Yuji Mochizuki
Publikováno v:
Journal of Chemical Information and Modeling
The worldwide spread of COVID-19 (new coronavirus found in 2019) is an emergent issue to be tackled. In fact, a great amount of works in various fields have been made in a rather short period. Here, we report a fragment molecular orbital (FMO) based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf10d512e5c462bbe82f166ef4fd76ab
https://doi.org/10.1021/acs.jcim.0c00283
https://doi.org/10.1021/acs.jcim.0c00283
Autor:
Kikuko Kamisaka, Tatsuya Ohyama, Chiduru Watanabe, Yuma Handa, Daisuke Takaya, Kaori Fukuzawa, Yusuke Kawashima, Koichiro Kato, Kazuki Watanabe, Ami Yamamoto, Teruki Honma
SARS-CoV-2 is the causative agent of coronavirus, globally known as COVID-19. There are ongoing researches to develop effective therapeutics and vaccines against COVID-19 using various methods. We currently conduct research based on the fragment mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::559c50451cf2575dc840236eaf084f1c
https://doi.org/10.33774/chemrxiv-2021-njqc8
https://doi.org/10.33774/chemrxiv-2021-njqc8
Autor:
Koji Okuwaki, Yuto Komeiji, Shigenori Tanaka, Yuji Mochizuki, Kaori Fukuzawa, Yoshio Okiyama, Kazuki Akisawa, Ryo Hatada, Yuma Handa
Publikováno v:
Applied Physics Express. 14:027003
A combination of classical molecular dynamics (MD) simulation and ab initio fragment molecular orbital (FMO) calculation was applied to a complex formed between the main protease of the new coronavirus and the inhibitor N3 to calculate interactions w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eff039c785614f35fdec59407bbe8bb4
https://doi.org/10.35848/1882-0786/abdac6
https://doi.org/10.35848/1882-0786/abdac6