Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Yum Shing Wong"'
Synergistic apoptosis-inducing effects on A375 human melanoma cells of natural borneol and curcumin.
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101277 (2014)
This study was to investigate the synergistic effect of NB/Cur on growth and apoptosis in A375 human melanoma cell line by MTT assay, flow cytometry and Western blotting. Our results demonstrated that NB effectively synergized with Cur to enhance its
Externí odkaz:
https://doaj.org/article/c782b01636c347a696c63a442a43c493
Autor:
Chaoran Liu, Zhong Liu, Meng Li, Xiaoling Li, Yum-Shing Wong, Sai-Ming Ngai, Wenjie Zheng, Yibo Zhang, Tianfeng Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53945 (2013)
Thioredoxin system plays an important role in regulation of intracellular redox balance and various signaling pathways. Thioredoxin reductase (TrxR) is overexpressed in many cancer cells and has been identified as a potential target of anticancer dru
Externí odkaz:
https://doaj.org/article/75e35f1f0bb744939fa6a0abfd412715
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63502 (2013)
Selenocystine (SeC) has been identified as a novel compound with broad-spectrum anticancer activities. Natural borneol (NB) is a monoterpenoid compound that has been used as a promoter of drug absorption. In the present study, we demonstrated that NB
Externí odkaz:
https://doaj.org/article/e1b76ff7834548dbadaff53fc1f5ad5c
Publikováno v:
Advanced Functional Materials. 30:2004630
Mesoporous silica nanoparticles (MSNs) have been well-demonstrated as excellent carriers for anticancer drug delivery. Presented here is a cancer-targeted MSNs drug delivery system that allows the direct fluorescence monitoring of the cellular uptake
Publikováno v:
Oncotarget
Doxorubicin-based chemotherapy represents one of the most effective ways in combating human cancers. However, its clinical use is limited by severe side effects. Selenocystine (SeC) is a natural available selenoamino acid with novel anticancer effica
Autor:
Yum Shing Wong, Shanyuan Zheng, Keith Kwong Hon Wong, Tianfeng Chen, Jun Sheng Zheng, Sai-Ming Ngai, Yibo Zhang, Zhi Huang, Wenjie Zheng
Publikováno v:
Molecular Pharmaceutics. 11:1282-1293
Cisplatin-based therapy is one of the most important chemotherapy treatments for cancers. However, its efficacy is greatly limited by drug resistance and undesirable side effects. Therefore, it is of great importance to develop chemosensitizing agent
Publikováno v:
J. Mater. Chem. B. 2:5409-5418
Selenium nanoparticles (SeNPs) have been widely used in various biomedical applications, including cancer therapy, diagnosis and drug delivery. Herein, we fabricated a novel type of structure-transformable capsules by decoration of SeNPs with folate-
Publikováno v:
Food Chemistry. 141:2385-2393
To fulfill the natural human needs of selenium, selenium biofortification has been carried out in rice (Oryza sativa) in recent years. Despite some improvements have been made, the increase of selenium content in rice was still limited and a large am
Autor:
Tianfeng Chen, Wenqiang Cao, Yi Wang, Cundong Fan, Yibo Zhang, Yum-Shing Wong, Wenjie Zheng, Jingjing Chen
Publikováno v:
Free Radical Biology and Medicine. 65:305-316
5-Fluorouracil (5-FU)-based chemotherapy as a first-line treatment is quite limited, because of its inefficiency and clinical resistance to it. The search for chemosensitizers that could augment its efficiency and overcome the drug resistance to 5-FU
Publikováno v:
Biomaterials. 34:7106-7116
Selenium nanoparticles (SeNPs) have garnered a great deal of attention as potential cancer therapeutic payloads. However, the in vivo targeting drug delivery has been challenging. Herein, we describe the synthesis of tansferrin (Tf)-conjugated SeNPs