Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Yulun Huang"'
Publikováno v:
Glioma, Vol 7, Iss 3, Pp 25-32 (2024)
Background and Aim: Glioma is one of the most prevalent and refractory brain cancers with a high recurrence rate. Current limitations of experimental in vitro models include their inability to remodel the heterogeneity of the parental tumors and thei
Externí odkaz:
https://doaj.org/article/501df231909c45e9aad4abc5a59a1efb
Autor:
Weichao Wang, Yang Zhang, Xuetao Li, Qinzi E, Zuoyu Jiang, Qikun Shi, Yu Huang, Jian Wang, Yulun Huang
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background The high invasiveness and infiltrative nature of Glioblastoma (GBM) pose significant challenges for surgical removal. This study aimed to investigate the role of KCNA1 in GBM progression. Methods CCK8, colony formation assay, scra
Externí odkaz:
https://doaj.org/article/8e401767466d40098850fc872327108c
Publikováno v:
Annals of Indian Academy of Neurology, Vol 27, Iss 3, Pp 325-327 (2024)
Externí odkaz:
https://doaj.org/article/2a3b9c7c37f348d7990eec93ac361169
Autor:
Huiyuan Zhang, Yuchen Du, Lin Qi, Sophie Xiao, Frank K. Braun, Mari Kogiso, Yulun Huang, Frank Huang, Aalaa Abdallah, Milagros Suarez, Sekar Karthick, Nabil M. Ahmed, Vita S. Salsman, Patricia A. Baxter, Jack M. Su, Daniel J. Brat, Paul L. Hellenbeck, Wan-Yee Teo, Akash J. Patel, Xiao-Nan Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Animal models representing different molecular subtypes of glioblastoma multiforme (GBM) is desired for developing new therapies. SVV-001 is an oncolytic virus selectively targeting cancer cells. It’s capacity of passing through
Externí odkaz:
https://doaj.org/article/f02330a7f677428e957a5b658a166efc
Autor:
Yang Zhang, Yunxiang Shao, Yanyan Li, Xuetao Li, Xuewen Zhang, Qinzhi E, Weichao Wang, Zuoyu Jiang, Wenjuan Gan, Yulun Huang
Publikováno v:
Cancer Medicine, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Background The intra‐ and inter‐tumoral heterogeneity of gliomas and the complex tumor microenvironment make accurate treatment of gliomas challenging. At present, research on gliomas mainly relies on cell lines, stem cell tumor spheres,
Externí odkaz:
https://doaj.org/article/035a143f38904af99de52682422eb4db
Autor:
Hsing-Hua Lai, Esther En-Shu Kuo, Ryh-Sheng Li, Tzu-Hsuan Chuang, Yao-Cheng Huang, Jhih-Yuan Hsieh, T. Arthur Chang, Yulun Huang, Wen-Ting Hsieh, Yan-Ru Su, Mark Liu
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 01, Pp 50-60 (2023)
Background: To demonstrate an interpretable machine learning (ML) model for a clinical prediction of corifollitropin alfa protocol. Methods: The retrospective study involved 1,221 cycles from 1,180 patients undergoing corifollitropin alfa protocol wi
Externí odkaz:
https://doaj.org/article/6afbb252d6664bb78b4d1b73c15f9254
Autor:
Xuetao Li, Guangliang Chen, Bin Liu, Zhennan Tao, Yue Wu, Kai Zhang, Zibin Feng, Yulun Huang, Hao Wang
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Glioma stem cells (GSCs) are the important cause of tumorigenesis, recurrence, and chemo(radio)resistance in glioma. Targeting GSCs helps improve the outcomes of glioma treatment. Polo-like kinase 1 (PLK1) is a member of the serine/threonine
Externí odkaz:
https://doaj.org/article/afe1fbaad69a437fbf92c18ea0f48a93
Autor:
Sibo Zhao, Jia Li, Huiyuan Zhang, Lin Qi, Yuchen Du, Mari Kogiso, Frank K. Braun, Sophie Xiao, Yulun Huang, Jianfang Li, Wan-Yee Teo, Holly Lindsay, Patricia Baxter, Jack M. F. Su, Adekunle Adesina, Miklós Laczik, Paola Genevini, Anne-Clemence Veillard, Sol Schvartzman, Geoffrey Berguet, Shi-Rong Ding, Liping Du, Clifford Stephan, Jianhua Yang, Peter J. A. Davies, Xinyan Lu, Murali Chintagumpala, Donald William Parsons, Laszlo Perlaky, Yun-Fei Xia, Tsz-Kwong Man, Yun Huang, Deqiang Sun, Xiao-Nan Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
While recurrence is frequent in ependymoma, the underlying molecular mechanisms remain to be explored. Here, the authors investigate epigenetic, genetic and tumorigenic changes in 30 patient-matched repeated relapses over 13 years and identify distin
Externí odkaz:
https://doaj.org/article/67ce4ebc1c4e4e89b80aca05d5ec1d5f
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
BackgroundFrailty caused by deterioration in multiple physiological systems has led to a significant increase in adverse events such as falls, disability, and death in frail older people. Similar to frailty, sarcopenia, defined as loss of skeletal mu
Externí odkaz:
https://doaj.org/article/2cf8a25240534194a3c106265be756de
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Abstract We determined the antitumor mechanism of apatinib in glioma using a patient-derived orthotopic xenograft (PDOX) glioma mouse model and glioblastoma (GBM) cell lines. The PDOX mouse model was established using tumor tissues from two glioma pa
Externí odkaz:
https://doaj.org/article/255716e465b0400a96622044d9e629c8