Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yuliya Zilberman"'
Publikováno v:
Genetics
Epithelial cells form intercellular junctions to strengthen cell–cell adhesion and limit diffusion, allowing epithelia to function as dynamic tissues and barriers separating internal and external environments. Junctions form as epithelial cells dif
Publikováno v:
Journal of Cell Biology. 216:3729-3744
During morphogenesis, adherens junctions (AJs) remodel to allow changes in cell shape and position while preserving adhesion. Here, we examine the function of Rho guanosine triphosphatase CDC-42 in AJ formation and regulation during Caenorhabditis el
Publikováno v:
Nature Cell Biology. 17:726-735
Nance and colleagues report that the E-cadherin HMR-1 recruits the RhoGAP PAC-1 to cell–cell contact and thereby drives symmetry breaking in C. elegans embryos.
Publikováno v:
The Journal of Cell Biology
Adherens junction remodeling allows changes in cell shape and position. Zilberman et al. show through live imaging that CDC-42 is dispensable for epithelial cell polarization, but its RhoGAP-regulated activity is needed to control junctional actin or
Autor:
Saadi Khochbin, Christoph Ballestrem, Michael M. Kozlov, Tom Shemesh, Benoit Gilquin, Letizia Carramusa, Antonina Y. Alexandrova, Yuliya Zilberman, Alexander D. Bershadsky, Alexander B. Verkhovsky
Publikováno v:
European Journal of Cell Biology. 85:165-173
Initial integrin-mediated cell-matrix adhesions (focal complexes) appear underneath the lamellipodia, in the regions of the "fast" centripetal flow driven by actin polymerization. Once formed, these adhesions convert the flow behind them into a "slow
Autor:
Yuliya Zilberman, Naila O. Alieva, Helena Sabanay, Stephanie Miserey-Lenkei, Zvi Kam, Alexander D. Bershadsky, Alexandra Lichtenstein
Publikováno v:
Molecular Biology of the Cell
A study of the role of actin cytoskeleton regulation in Golgi organization and function shows that Rho regulates Golgi fragmentation into ministacks, as well as formation of Rab6-positive Golgi-derived vesicles, via mDia1 formin activation. The Rho
Autor:
Christoph Ballestrem, Yuliya Zilberman, Ralph Mazitschek, Saadi Khochbin, Letizia Carramusa, Alexander D. Bershadsky
Publikováno v:
Journal of Cell Science
We studied the role of a class II histone deacetylase, HDAC6, known to function as a potent α-tubulin deacetylase, in the regulation of microtubule dynamics. Treatment of cells with the class I and II histone deacetylase inhibitor TSA, as well as th