Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Yuliy Y. Chirkov"'
Autor:
Cher-Rin Chong, Saifei Liu, Hasan Imam, Tamila Heresztyn, Benedetta C. Sallustio, Yuliy Y. Chirkov, John D. Horowitz
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2381 (2022)
Perhexiline (Px) inhibits carnitine palmitoyltransferase 1 (CPT1), which controls uptake of long chain fatty acids into mitochondria. However, occasional cases of hypoglycaemia have been reported in Px-treated patients, raising the possibility that P
Externí odkaz:
https://doaj.org/article/16192a80b61d451681f8dc806e980bc9
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9273
Impairment of the nitric oxide/soluble guanylate cyclase (NO)/sGC) signalling cascade is associated with many forms of cardiovascular disease, resulting not only in compromised vasodilatation but also loss of anti-aggregatory homeostasis. Myocardial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dd5337ebaec526b5d538b34758abd7
https://doi.org/10.3390/ijms24119273
https://doi.org/10.3390/ijms24119273
Publikováno v:
Thrombosis Research. 196:510-515
Introduction On-treatment platelet aggregability represents the major form of functional assessment for patients treated with P2Y12 receptor antagonists, with “high” on-treatment platelet aggregability (HTPA) predicting thrombotic risk. However H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b9996474d45091e91755b11b6334d2
https://doi.org/10.1016/j.thromres.2020.10.009
https://doi.org/10.1016/j.thromres.2020.10.009
Autor:
Jeanette Stansborough, John D. Horowitz, Cher-Rin Chong, Yuliy Y. Chirkov, Saifei Liu, D. Ngo
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 2250-2257 (2020)
Aims Takotsubo syndrome (TTS) episodes are primarily initiated by ‘pulse’ release of catecholamines inducing neutrophil infiltration and myocardial inflammation in susceptible individuals (largely ageing women). Evidence of myocardial inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdcaa6f3518a909fc0528c74840d910
https://doi.org/10.1002/ehf2.12729
https://doi.org/10.1002/ehf2.12729
Autor:
John D Horowitz, Yuliy Y Chirkov, Angela M Kucia, Thanh Ha Nguyen, Gao-Jing Ong, Sven Y Surikow, Olivia C Girolamo
Refereed/Peer-reviewed Since its initial description by Japanese investigators 30 years ago, TakoTsubo Syndrome (TTS) has variously been regarded as a form of acute coronary syndrome and also as a form of cardiomyopathy (or more accurately, a myocard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b389155e1d63a21aeaedad16a69a887e
https://hdl.handle.net/11541.2/31343
https://hdl.handle.net/11541.2/31343
Autor:
Cher-Rin Chong, Saifei Liu, Hasan Imam, Tamila Heresztyn, Benedetta Sallustio, Yuliy Y Chirkov, John D Horowitz
Purpose: Perhexiline (Px) has previously been utilized primarily in the treatment of otherwise refractory angina pectoris and/or systolic heart failure. In recent years, Px has also shown increasing promise as a potential chemotherapeutic agent. Px i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d5e1ecf86b59a9b7233ef9e46055ceb
https://doi.org/10.21203/rs.3.rs-1149918/v1
https://doi.org/10.21203/rs.3.rs-1149918/v1
Autor:
John D. Horowitz, Viviane Caceres, Gao-Jing Ong, Yuliy Y. Chirkov, Thanh H Nguyen, Olivia Girolamo, Armin Muminovic
Publikováno v:
Expert review of cardiovascular therapy. 19(10)
Introduction Since Prinzmetal first described a "variant" form of angina pectoris, with predominantly resting episodes of pain and cyclic severity variations, it has gradually become apparent that this clinical presentation is caused by episodes of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be5205449b80a7001518108b452e91d
https://pubmed.ncbi.nlm.nih.gov/34633245
https://pubmed.ncbi.nlm.nih.gov/34633245
Autor:
Margaret Arstall, Yuliy Y. Chirkov, C. Ajaero, Tamila Heresztyn, Andrew D. McGavigan, Michael P. Frenneaux, John D. Horowitz, Nathan E.K. Procter
Publikováno v:
Heart and Vessels. 35:197-206
To determine (a) whether chronic heart failure with reduced ejection fraction (HFrEF) is associated with increased glycocalyx shedding; (b) whether glycocalyx shedding in HFrEF with left ventricular dyssynchrony is related to inflammation, endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b1d05363067ff868e29f98e6a04b1f0
https://doi.org/10.1007/s00380-019-01481-3
https://doi.org/10.1007/s00380-019-01481-3
Autor:
Thanh H Nguyen, Sven Y. Surikow, Karin Schenck-Gustafsson, Yuliy Y. Chirkov, Cher-Rin Chong, Angela M Kucia, Michael P. Frenneaux, Gao Jing Ong, Olivia Girolamo, Saifei Liu, John D. Horowitz
Publikováno v:
Heart, Lung and Circulation
It is now 30 years since Japanese investigators first described Takotsubo Syndrome (TTS) as a disorder occurring mainly in ageing women, ascribing it to the impact of multivessel coronary artery spasm. During the intervening period, it has become cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdcd03626d0abdcc697b96040e7e3b6d
Autor:
Thanh H Nguyen, H. Imam, Irene Stafford, John D. Horowitz, Tamila Heresztyn, Saifei Liu, Yuliy Y. Chirkov
Publikováno v:
British journal of pharmacologyREFERENCES. 178(7)
BACKGROUND AND PURPOSE The pathophysiology of coronary artery spasm (CAS), with its associated ischaemic crises, is currently poorly understood and treatment is frequently ineffective. In view of increasing evidence that platelet-based defects may oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8521b5676150a7a4ed6951508f0cd79e
https://pubmed.ncbi.nlm.nih.gov/33486763
https://pubmed.ncbi.nlm.nih.gov/33486763