Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yuliana Mihaylova"'
Autor:
Yuliana Mihaylova, Prasad Abnave, Damian Kao, Samantha Hughes, Alvina Lai, Farah Jaber-Hijazi, Nobuyoshi Kosaka, A. Aziz Aboobaker
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The Mll3/4 histone methyltransferases can act as tumour suppressors in humans. Here, the authors identify three orthologs of mammalian MLL3/4 in the planarian Schmidtea mediterranea and show that knockdown causes outgrowths in regenerating animals, s
Externí odkaz:
https://doaj.org/article/d6b21974aa2f41b0889a0c888a7d36c3
Autor:
Jordi Solana, Chiara Gamberi, Yuliana Mihaylova, Stefanie Grosswendt, Chen Chen, Paul Lasko, Nikolaus Rajewsky, A Aziz Aboobaker
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004003 (2013)
Post-transcriptional regulatory mechanisms are of fundamental importance to form robust genetic networks, but their roles in stem cell pluripotency remain poorly understood. Here, we use freshwater planarians as a model system to investigate this and
Externí odkaz:
https://doaj.org/article/abdf09860e404e67b708f4fb5b83144b
Variations in the microbial composition of the mouth (the oral microbiome) have known associations with dental and systemic disease. While this is relatively well understood in humans, research on this topic in companion animals, and in cats in parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c350ce8259852a0101e356758f1d7a
https://doi.org/10.1101/2021.04.23.441192
https://doi.org/10.1101/2021.04.23.441192
The COVID-19 pandemic has presented multiple healthcare challenges, one of which is adequately meeting the need for large-scale diagnostic testing. The most commonly used assays for detection of SARS-CoV-2, including those recommended by the Center f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7ee6a6b790427ebc9aa9795b2ce4541
https://doi.org/10.1101/2020.11.21.20236216
https://doi.org/10.1101/2020.11.21.20236216
Autor:
Sounak Sahu, Samantha Jane Hughes, Damian Kao, Alvina G. Lai, Yuliana Mihaylova, A. Aziz Aboobaker, Anish Dattani, Prasad Abnave
Planarian flatworms have an indefinite capacity to regenerate missing or damaged body parts owing to a population of pluripotent adult stems cells called neoblasts (NBs). Currently, little is known about the importance of the epigenetic status of NBs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31e88036e565a7de6ec30560fa10cfc
https://europepmc.org/articles/PMC6169894/
https://europepmc.org/articles/PMC6169894/
Autor:
Alvina G. Lai, A. Aziz Aboobaker, Prasad Abnave, Damian Kao, Samantha Jane Hughes, Farah Jaber-Hijazi, Nobuyoshi Kosaka, Yuliana Mihaylova
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Currently, little is known about the evolution of epigenetic regulation in animal stem cells. Here we demonstrate, using the planarian stem cell system to investigate the role of the COMPASS family of MLL3/4 histone methyltransferases that their func
Autor:
A. Aziz Aboobaker, Yuliana Mihaylova
Publikováno v:
Genome Biology
Background Notophthalmus viridescens, an urodelian amphibian, represents an excellent model organism to study regenerative processes, but mechanistic insights into molecular processes driving regeneration have been hindered by a paucity and poor anno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03f87e71d0e07b2ed418be689f36abbf
https://doi.org/10.1186/gb-2013-14-2-106
https://doi.org/10.1186/gb-2013-14-2-106
Autor:
Belen Tejada-Romero, A. Aziz Aboobaker, Bjoern Neumann, Yuliana Mihaylova, Jean-Michel Carter
Publikováno v:
Development.
Regeneration involves the integration of new and old tissues in the context of an adult life history. It is clear that the core conserved signaling pathways that orchestrate development also play central roles in regeneration and further study of con
Autor:
Sunir Malla, A. Aziz Aboobaker, Belen Tejada Romero, Priscilla J.K.P. Lo, Jordi Solana, Yuliana Mihaylova, Jack S. Benner, Chen Chen, Alexey Ruzov, Jeremy M. Foster, Farah Jaber-Hijazi
Publikováno v:
Developmental Biology
Planarian adult stem cells (pASCs) or neoblasts represent an ideal system to study the evolution of stem cells and pluripotency as they underpin an unrivaled capacity for regeneration. We wish to understand the control of differentiation and pluripot
Autor:
A. Aziz Aboobaker, Paul Lasko, Stefanie Grosswendt, Nikolaus Rajewsky, Yuliana Mihaylova, Jordi Solana, Chen Chen, Chiara Gamberi
Publikováno v:
PLoS Genetics, Vol 9, Iss 12, p e1004003 (2013)
PLoS Genetics
PLoS Genetics
Post-transcriptional regulatory mechanisms are of fundamental importance to form robust genetic networks, but their roles in stem cell pluripotency remain poorly understood. Here, we use freshwater planarians as a model system to investigate this and