Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yuliana K. Bosken"'
Autor:
Rebecca N. D’Amico, Yuliana K. Bosken, Kathleen F. O’Rourke, Alec M. Murray, Woudasie Admasu, Chia-en A. Chang, David D. Boehr
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Networks of noncovalent amino acid interactions propagate allosteric signals throughout proteins. Tryptophan synthase (TS) is an allosterically controlled bienzyme in which the indole product of the alpha subunit (αTS) is transferred through a 25 Å
Externí odkaz:
https://doaj.org/article/2ebbcdaede4741bf8dc39da2cd8100d3
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Covid-19 is caused by a novel form of coronavirus for which there are currently no vaccines or anti-viral drugs. This virus, termed SARS-CoV-2 (CoV2), contains Papain-like protease (PLpro) involved in viral replication and immune response evasion. Dr
Externí odkaz:
https://doaj.org/article/9cddcdaeb1704f7abb5ea5a84f1160b5
Autor:
Yuliana K. Bosken, Huanbin Zhou, Li Fan, Chia-en A. Chang, Wenbo Ma, Leonard J. Mueller, Shih-Hsin Kan, Rittik K. Ghosh, Eduardo Hilario, Michael F. Dunn, Dimitri Niks, Rizi Ai
Publikováno v:
Protein Sci
Antibiotic and antimicrobial resistance is a continually growing challenge in the treatment of various bacterial infections worldwide. New drugs and new drug targets are necessary to curb the threat of infectious diseases caused by multidrug-resistan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ab6b00a07ca389633351a96410ff9e
https://doi.org/10.1002/pro.4236
https://doi.org/10.1002/pro.4236
Autor:
Jacob B. Holmes, Viktoriia Liu, Bethany G. Caulkins, Eduardo Hilario, Rittik K. Ghosh, Victoria N. Drago, Robert P. Young, Jennifer A. Romero, Adam D. Gill, Paul M. Bogie, Joana Paulino, Xiaoling Wang, Gwladys Riviere, Yuliana K. Bosken, Jochem Struppe, Alia Hassan, Jevgeni Guidoulianov, Barbara Perrone, Frederic Mentink-Vigier, Chia-en A. Chang, Joanna R. Long, Richard J. Hooley, Timothy C. Mueser, Michael F. Dunn, Leonard J. Mueller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 2
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance The determination of active site protonation states is critical for a full mechanistic understanding of enzymatic transformations. However, hydrogen atom positions are challenging to extract using the standard tools of structural biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d7608d5aac5e21b95efa8324291114
https://doi.org/10.1073/pnas.2109235119
https://doi.org/10.1073/pnas.2109235119
Autor:
Rittik K. Ghosh, Viktoriia Liu, Chia-en A. Chang, Jevgeni Guidoulianov, Gwladys Riviere, Leonard J. Mueller, Frederic Mentink-Vigier, Adam D. Gill, Bethany G. Caulkins, Timothy C. Mueser, Robert P. Young, Barbara Perrone, Alia Hassan, Michael F. Dunn, Xiaoling Wang, Jennifer Romero, Jochem Struppe, Richard J. Hooley, Joanna R. Long, Eduardo Hilario, Victoria N. Drago, Jacob B. Holmes, Yuliana K. Bosken, Joana Paulino, Paul M. Bogie
NMR-assisted crystallography – the synergistic combination of solid-state NMR, X-ray crystallography, and first-principles computational chemistry – holds remarkable promise for mechanistic enzymology: by providing atomic-resolution characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55fe2cbdcc5bcfcb45a194207a8354da
https://doi.org/10.1101/2021.05.12.443852
https://doi.org/10.1101/2021.05.12.443852
Autor:
Alec M. Murray, Yuliana K. Bosken, Chia-en A. Chang, David D. Boehr, Rebecca N. D'Amico, Kathleen F. O'Rourke
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23c2892f5ed5cf21327fda028dcca525
https://doi.org/10.1096/fasebj.2020.34.s1.09596
https://doi.org/10.1096/fasebj.2020.34.s1.09596
Autor:
Debashish Sahu, David D. Boehr, Chia-en A. Chang, Kathleen F. O'Rourke, Rebecca N. D'Amico, Yuliana K. Bosken
Publikováno v:
Structure (London, England : 1993). 27(9)
Networks of noncovalent interactions are important for protein structural dynamics. We used nuclear magnetic resonance chemical shift covariance analyses on an inactive variant of the alpha subunit of tryptophan synthase to map amino acid interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ce996c80ccd8db5ba8c50f05711f7d
https://pubmed.ncbi.nlm.nih.gov/31257109
https://pubmed.ncbi.nlm.nih.gov/31257109