Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yulia Yuzenkova"'
Publikováno v:
Royal Society Open Science, Vol 8, Iss 5 (2021)
Recent years witnessed the discovery of ubiquitous and diverse 5′-end RNA cap-like modifications in prokaryotes as well as in eukaryotes. These non-canonical caps include metabolic cofactors, such as NAD+/NADH, FAD, cell wall precursors UDP-GlcNAc,
Externí odkaz:
https://doaj.org/article/9471e306fcb24588b269167069137f6f
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Although all known RNA polymerases have multiple subunits, unrelated single-subunit polymerases have also been described. Here, the authors describe a single-subunit RNA polymerase from the SPβ prophage ofBacillus subtilis, which shares homology to
Externí odkaz:
https://doaj.org/article/4abbf065273c4346b765c501e0066613
Autor:
Nikolay Zenkin, Yulia Yuzenkova
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1195-1209 (2015)
Transcription elongation is regulated at several different levels, including control by various accessory transcription elongation factors. A distinct group of these factors interacts with the RNA polymerase secondary channel, an opening at the enzym
Externí odkaz:
https://doaj.org/article/258feeb8e9b640839cd5cc7179a29043
Autor:
Liqiang Shen, Giorgio Lai, Linlin You, Jing Shi, Xiaoxian Wu, Maria Puiu, Zhanxi Gu, Yu Feng, Yulia Yuzenkova, Yu Zhang
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Multisubunit RNA polymerases (RNAPs) associate with initiation factors (σ in bacteria) to start transcription. The σ factors are responsible for recognizing and unwinding promoter DNA in all bacterial RNAPs. Here, we report two cryo-EM structures o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7cc185449d76762c7b981671873f613
https://doi.org/10.1073/pnas.2219290120
https://doi.org/10.1073/pnas.2219290120
Recently discovered ability of various RNA polymerases (RNAPs) of bacteria and eukaryotes to initiate RNA synthesis with cofactors such as NAD+/NADH (nicotinamide adenine dinucleotide). This phenomenon was quickly dubbed “non-canonical capping” a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffcb007b4ace0a665a1fdd3afde7fbad
https://doi.org/10.1101/2023.03.31.535138
https://doi.org/10.1101/2023.03.31.535138
Autor:
Liqiang Shen, Giorgio Lai, Linlin You, Jing Shi, Xiaoxian Wu, Maria Puiu, Zhanxi Gu, Yu Feng, Yulia Yuzenkova, Yu Zhang
SUMMARYMulti-subunit RNA polymerases (RNAPs) associate with initiation factors (σ in bacteria) to start transcription. The σ factors are responsible for recognizing and unwinding promoter DNA in all bacterial RNAPs. Here, we report two cryo-EM stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c524775f78966e00b5f0aaa58f445cb4
https://doi.org/10.1101/2022.10.06.511230
https://doi.org/10.1101/2022.10.06.511230
Publikováno v:
Royal Society Open Science, Vol 8, Iss 5 (2021)
Royal Society Open Science
Royal Society Open Science
Recent years witnessed the discovery of ubiquitous and diverse 5′-end RNA cap-like modifications in prokaryotes as well as in eukaryotes. These non-canonical caps include metabolic cofactors, such as NAD+/NADH, FAD, cell wall precursors UDP-GlcNAc,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4061dcb2f772c4d8adebbcde5d3229
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184783
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184783
Publikováno v:
Nucleic Acids Research
To initiate replication on a double-stranded DNA de novo, all organisms require primase, an RNA polymerase making short RNA primers which are then extended by DNA polymerases. Here, we show that primase can use metabolic cofactors as initiating subst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe33f8cecaf6d280c54d9c6323fa745
https://pubmed.ncbi.nlm.nih.gov/32463447
https://pubmed.ncbi.nlm.nih.gov/32463447
Publikováno v:
Nucleic Acids Research
The vast majority of organisms possess transcription elongation factors, the functionally similar bacterial Gre and eukaryotic/archaeal TFIIS/TFS. Their main cellular functions are to proofread errors of transcription and to restart elongation via st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ba91fe32c6e5e7e10c6c29a0087ef5
https://nrl.northumbria.ac.uk/id/eprint/41965/1/gkz1130.pdf
https://nrl.northumbria.ac.uk/id/eprint/41965/1/gkz1130.pdf
Autor:
Christina Julius, Yulia Yuzenkova
Recently a new, non-canonical type of 5’-RNA capping with cellular metabolic cofactors was discovered in bacteria and eukaryotes. This type of capping is performed by RNA polymerases, the main enzymes of transcription, which initiate RNA synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c38a59d696558610b470d16b3381f6