Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yulia N. Demchenko"'
Autor:
W. M. Kuehl, Yan W. Asmann, Anna V. Roschke, Peter Leif Bergsagel, Yulia N. Demchenko, Wei Dong Chen
Publikováno v:
Nucleic Acids Research
Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf1aac0577069393536bbb5f7a2a3bf
https://doi.org/10.1093/nar/gkw527
https://doi.org/10.1093/nar/gkw527
Autor:
Ana Gabrea, Gina Y. Kim, W. Michael Kuehl, Yulia N. Demchenko, Leif Bergsagel, Anna V. Roschke
Publikováno v:
Genes, Chromosomes and Cancer. 53:467-474
Primary IGH translocations involving seven recurrent partner loci and oncogenes are present in about 40% of multiple myeloma tumors. Secondary IGH rearrangements, which occur in a smaller fraction of tumors, usually are complex structures, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55101af67b4ff1a625e9937ca9ccab68
https://doi.org/10.1002/gcc.22158
https://doi.org/10.1002/gcc.22158
Autor:
Daniel L. Riggs, Jonathan J Keats, Victoria M. Garbitt, P L Bergsagel, S Van Wier, K Tamizhmani, Yulia N. Demchenko, Leslie A. Brents, A V Roschke, W. M. Kuehl, Maurizio Affer, W D Chen, Marta Chesi, R Fonseca
Publikováno v:
Leukemia
MYC locus rearrangements-often complex combinations of translocations, insertions, deletions and inversions-in multiple myeloma (MM) were thought to be a late progression event, which often did not involve immunoglobulin genes. Yet, germinal center a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e3e1a69cd9ed8cd116f37d762bd79f
https://doi.org/10.1038/leu.2014.70
https://doi.org/10.1038/leu.2014.70
Autor:
W. Michael Kuehl, Yulia N. Demchenko
Publikováno v:
Oncotarget
NFkB transcription factors play a key role in the survival and proliferation of many kinds of B-cell tumors, including multiple myeloma (MM). It was shown that NFkB activation in MM tumors results mainly from extrinsic signaling by APRIL and BAFF lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e874c74789dd6aa6508e6dac6b2677b9
https://doi.org/10.18632/oncotarget.109
https://doi.org/10.18632/oncotarget.109
Autor:
P. Leif Bergsagel, Yulia N. Demchenko, W. Michael Kuehl, Jonathan J Keats, Oleg K. Glebov, Adriana Zingone
Publikováno v:
Blood. 115:3541-3552
Mutations involving the nuclear factor-κB (NF-κB) pathway are present in at least 17% of multiple myeloma (MM) tumors and 40% of MM cell lines (MMCLs). These mutations, which are apparent progression events, enable MM tumors to become less dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be84641cb872eec3b4ea75a26a0c2f3
https://doi.org/10.1182/blood-2009-09-243535
https://doi.org/10.1182/blood-2009-09-243535
Autor:
Leslie A. Brents, Lawrence R. McGee, Zhihong Li, Yulia N. Demchenko, Leif Bergsagel, Michael Kuehl
Publikováno v:
Oncotarget
NFkB activity is critical for survival and proliferation of normal lymphoid cells and many kinds of B-cell tumors, including multiple myeloma (MM). NFkB activating mutations, which are apparent progression events, enable MM tumors to become less depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8329be6a1b64dd0a582f6158fcf9c366
https://pubmed.ncbi.nlm.nih.gov/24980832
https://pubmed.ncbi.nlm.nih.gov/24980832
Autor:
W. M. Kuehl, Yulia N. Demchenko
Publikováno v:
Cancer Research. 73:2099-2099
NFkB activity is critical for survival and proliferation of normal lymphoid cells and many kinds of B-cell tumors, including multiple myeloma (MM). NFkB activating mutations, which are apparent progression events, enable MM tumors to become less depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5212a01a15318d49611821214aa0fc57
https://doi.org/10.1158/1538-7445.am2013-2099
https://doi.org/10.1158/1538-7445.am2013-2099