Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yulia Manenkova"'
Autor:
Ghanashyam Sarikonda, Sowbarnika Sachithanantham, Yulia Manenkova, Tinalyn Kupfer, Amanda Posgai, Clive Wasserfall, Philip Bernstein, Laura Straub, Philippe P Pagni, Darius Schneider, Teresa Rodriguez Calvo, Marilyne Coulombe, Kevan Herold, Ronald G Gill, Mark Atkinson, Gerald Nepom, Mario Ehlers, Teodora Staeva, Hideki Garren, Lawrence Steinman, Andrew C Chan, Matthias von Herrath
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54712 (2013)
A recent type 1 diabetes (T1D) clinical trial of rituximab (a B cell-depleting anti-CD20 antibody) achieved some therapeutic benefit in preserving C-peptide for a period of approximately nine months in patients with recently diagnosed diabetes. Our p
Externí odkaz:
https://doaj.org/article/de59e6efcbf84a03a25062ac99797d76
Autor:
Philip Bernstein, Matthias von Herrath, Clive Wasserfall, Teodora Staeva, Philippe P. Pagni, Yulia Manenkova, Kevan C. Herold, Laura Straub, Mario R. Ehlers, Amira Bel Hani, Amanda L. Posgai, Ronald G. Gill, Tinalyn Kupfer, Songyan Deng, Mark A. Atkinson, Gerald T. Nepom
Publikováno v:
Diabetes. 65:1310-1316
There is an ongoing need to develop strategic combinations of therapeutic agents to prevent type 1 diabetes (T1D) or to preserve islet β-cell mass in new-onset disease. Although clinical trials using candidate therapeutics are commonly based on prec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36411722484d0435d1b96d38ac175e3
https://doi.org/10.2337/db15-0492
https://doi.org/10.2337/db15-0492
Autor:
Teresa Rodriguez-Calvo, Amira Bel Hani, Alecia Blaszczak, Sina Faton, Natalie Amirian, Damien Bresson, Matthias von Herrath, Philippe P. Pagni, Yulia Manenkova, Sowbarnika Sachithanantham
Publikováno v:
Diabetes
Type 1 diabetes is thought to be an autoimmune condition in which self-reactive T cells attack insulin-secreting pancreatic β-cells. As a proinflammatory cytokine produced by β-cells or macrophages, interleukin-1β (IL-1β) represents a potential t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506322d0a2e42b936cf6378b10b6b914
http://europepmc.org/articles/PMC4030110
http://europepmc.org/articles/PMC4030110
Autor:
Argyrios N. Theofilopoulos, Dwight H. Kono, Michael Berger, Virginie Tardif, Kasper Hoebe, Brian R. Lawson, Yulia Manenkova, Chong Yuan, Jianping Zuo
Publikováno v:
Clinical Immunology. 147:133-143
Post-translational protein modifications can play a significant role in immune cell signaling. Recently, we showed that inhibition of transmethylation curtails experimental autoimmune encephalomyelitis, notably by reducing T cell receptor (TCR)-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49f442c784bc2c4d9e05efa8fd87897
https://doi.org/10.1016/j.clim.2013.02.018
https://doi.org/10.1016/j.clim.2013.02.018
Autor:
Jasimuddin Ahamed, Xiao-Ru Chen, Jian Ping Zou, Argyrios N. Theofilopoulos, Yulia Manenkova, Chong Yuan, Brian R. Lawson, Roberto Baccala
Publikováno v:
The Journal of Immunology. 178:5366-5374
Transmethylation affects several cellular events, including T cell activation, and blockade of this pathway may curtail inflammatory/autoimmune responses. Here, we demonstrate that transmethylation inhibition by a novel reversible S-adenosyl-l-homocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118eefaebad68469a4837fe5d535a230
https://doi.org/10.4049/jimmunol.178.8.5366
https://doi.org/10.4049/jimmunol.178.8.5366
Autor:
Iain L. Campbell, Yulia Manenkova, Philippe P. Pagni, Haiqing Zhang, Sowbarnika Sachithanantham, Bret Morin, Amira Bel Hani, Cheng Yang, Matthias von Herrath, Tom Van Belle, Natalie Amirian, Amy Dave, Jeanette Liao
Publikováno v:
Journal of autoimmunity. 55
Inflammatory mechanisms play a key role in the pathogenesis of type 1 and type 2 diabetes. IL6, a pleiotropic cytokine with impact on immune and non-immune cell types, has been proposed to be involved in the events causing both forms of diabetes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c90248470bfb76526b2a2624ccc8a1
https://pubmed.ncbi.nlm.nih.gov/24582317
https://pubmed.ncbi.nlm.nih.gov/24582317
Autor:
Lawrence Steinman, Sowbarnika Sachithanantham, Mark A. Atkinson, Marilyne Coulombe, Hideki Garren, Ghanashyam Sarikonda, Mario R. Ehlers, Yulia Manenkova, Teodora Staeva, Philip Bernstein, Gerald T. Nepom, Teresa Rodriguez Calvo, Darius A. Schneider, Clive Wasserfall, Ronald G. Gill, Tinalyn Kupfer, Kevan C. Herold, Andrew C. Chan, Philippe P. Pagni, Matthias von Herrath, Laura Straub, Amanda L. Posgai
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54712 (2013)
PLoS ONE
PLoS ONE
A recent type 1 diabetes (T1D) clinical trial of rituximab (a B cell-depleting anti-CD20 antibody) achieved some therapeutic benefit in preserving C-peptide for a period of approximately nine months in patients with recently diagnosed diabetes. Our p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49181466fb83861299602a37ecba497
http://europepmc.org/articles/PMC3566105?pdf=render
http://europepmc.org/articles/PMC3566105?pdf=render
To enhance efficacy of forthcoming type 1 diabetes (T1D) clinical trials, combination therapies (CTs) are envisaged. In this study, we showed that efficacy of a CT, using anti-CD3 antibody and glutamic acid decarboxylase of 65 kd (GAD65)-expressing p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69b2e6c7d448b08c95de976f5860116
https://europepmc.org/articles/PMC2818225/
https://europepmc.org/articles/PMC2818225/
Autor:
Yulia Manenkova, Lisl K. M. Shoda, Jason P. Chan, Matthias von Herrath, Richard Ho, Damien Bresson, Alusha A. Mamchak
Publikováno v:
Clinical Immunology. 135:S99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14eae91aedce44164389b28e9d350f44
https://doi.org/10.1016/j.clim.2010.03.296
https://doi.org/10.1016/j.clim.2010.03.296