Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yulia Katsman"'
Autor:
Pei Lin Shi, Beth Binnington, Darinka Sakac, Yulia Katsman, Stephanie Ramkumar, Jean Gariepy, Minji Kim, Donald R. Branch, Clifford Lingwood
Publikováno v:
Toxins, Vol 4, Iss 12, Pp 1517-1534 (2012)
Our previous genetic, pharmacological and analogue protection studies identified the glycosphingolipid, Gb3 (globotriaosylceramide, Pk blood group antigen) as a natural resistance factor for HIV infection. Gb3 is a B cell marker (CD77), but a fractio
Externí odkaz:
https://doaj.org/article/f6c9c7b20bd246a3a12be8a2ddda1939
Autor:
Sai Kumar Chakka, Yulia Katsman, Noruê Salum, Angelica M. Bello, Iain Scovell, Madeleine C. Bareau, Donald R. Branch, Anton Neschadim, Lakshmi P. Kotra, Meena K. Purohit
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:2739-2752
Idiopathic or immune thrombocytopenia (ITP) is a serious clinical disorder involving the destruction of platelets by macrophages. Small molecule therapeutics are highly sought after to ease the burden on current therapies derived from human sources.
Autor:
Yulia Katsman, Xue-Zhong Ma, Fabian Käsermann, Donald R. Branch, Danila Leontyev, Sylvia Miescher
Publikováno v:
Transfusion. 52:1799-1805
BACKGROUND: Sialylation of the N-linked glycan on asparagine-297 within the Fc region of intravenous gammaglobulins (IVIgs) was shown to be necessary for efficacy of IVIg in the amelioration of experimental inflammatory arthritis. To test the role fo
Improved mouse models for the study of treatment modalities for immune-mediated platelet destruction
Publikováno v:
Transfusion. 50:1285-1294
BACKGROUND: We found when using a mouse model of immune thrombocytopenia (ITP) that platelet (PLT) nadir could not be maintained in the face of daily PLT antibody, making interpretation of treatment modalities difficult. This finding was documented t
Autor:
Cécile Chagneau, Yulia Katsman, Richard Francis Langler, Anna Glistvain, Andrew S. Kruspe, Darinka Sakac, Donald R. Branch
Publikováno v:
Transfusion. 49:928-936
BACKGROUND We have investigated whether chemicals known to disrupt disulfide bonds are capable of altering immunoglobulin anti-D structure resulting in an increased efficacy of the chemically modified anti-D to inhibit Fcgamma receptor (FcgammaR)-med
Autor:
Robert Sugar, Yulia Katsman, Elodie Darbo, Moorthy Sakthidevi, Lucas Brandon Edelman, Kristina Tabbada, Stefan Schoenfelder, Emilia Dimitrova, Biola M. Javierre, Filipe Tavares-Cadete, Borbala Mifsud, Simon Andrews, Andy Higgs, Bram Herman, Mayra Furlan-Magaril, Andrew Dimond, Peter Fraser, Steven W. Wingett, Jennifer A. Mitchell, Takashi Nagano, Cameron S. Osborne, Sarah Elderkin, Nicholas M. Luscombe, Emily M LeProust
Publikováno v:
Schoenfelder, S, Furlan-Magaril, M, Mifsud, B, Tavares-Cadete, F, Sugar, R, Javierre, B M, Nagano, T, Katsman, Y, Sakthidevi, M, Wingett, S W, Dimitrova, E, Dimond, A, Edelman, L B, Elderkin, S, Tabbada, K, Darbo, E, Andrews, S, Herman, B, Higgs, A, LeProust, E, Osborne, C S, Mitchell, J A, Luscombe, N M & Fraser, P 2015, ' The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements ', Genome Research, vol. 25, no. 4, pp. 582-597 . https://doi.org/10.1101/gr.185272.114
The mammalian genome harbors up to one million regulatory elements often located at great distances from their target genes. Long-range elements control genes through physical contact with promoters and can be recognized by the presence of specific h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2ccf57a8f11b50085f974465e22d2b
https://kclpure.kcl.ac.uk/en/publications/8761bfcd-0f00-4ac1-9dfb-aac6b8b6650b
https://kclpure.kcl.ac.uk/en/publications/8761bfcd-0f00-4ac1-9dfb-aac6b8b6650b
Autor:
Annie Roy, Garnet Suck, Nathalie Dussault, Sonia Néron, Claudia Racine, Donald R. Branch, Xue-Zhong Ma, Yulia Katsman, Darinka Sakac
Publikováno v:
International Immunology. 18:375-387
Resting normal human B cells express negligible c-src mRNA or Src protein tyrosine kinase; however, upon induction of proliferation, these cells express high levels of both mRNA and protein and show a concomitant increase in tyrosine kinase activity
Autor:
Moorthy Sakthidevi, Neil Macpherson, Felicia Collura, Navroop K. Dhaliwal, Harry Y. Zhou, Yulia Katsman, Jennifer A. Mitchell, Scott Davidson
Publikováno v:
Genesdevelopment. 28(24)
The Sox2 transcription factor must be robustly transcribed in embryonic stem (ES) cells to maintain pluripotency. Two gene-proximal enhancers, Sox2 regulatory region 1 (SRR1) and SRR2, display activity in reporter assays, but deleting SRR1 has no eff
Autor:
Xue-Zhong Ma, Meenakshi Bali, Soad Fahim, Tianru Jin, Xin Zhang, Darinka Sakac, Yulia Katsman, Donald R. Branch
Publikováno v:
Experimental Hematology. 31:131-142
Objective SHP-1 protein tyrosine phosphatase has been implicated in suppressing B-lymphocyte and myeloid cell malignancies; however, there are little data on this role of SHP-1 in T-lymphocyte malignancies. We examined malignant human T cells to iden
Autor:
Yulia Katsman, Donald R. Branch, Iain Scovell, Anton Neschadim, Meena K. Purohit, Lakshmi P. Kotra
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(8)
Immune thrombocytopenia (ITP) is caused by production of an autoantibody to autologous platelets. ITP can be treated either by reducing platelet destruction or by increasing platelet production. Fcγ receptor mediated phagocytosis of the opsonized bl