Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Yulia Haim"'
Autor:
Gil Sorek, Yulia Haim, Vered Chalifa-Caspi, Or Lazarescu, Maya Ziv-Agam, Tobias Hagemann, Pamela Arielle Nono Nankam, Matthias Blüher, Idit F. Liberty, Oleg Dukhno, Ivan Kukeev, Esti Yeger-Lotem, Assaf Rudich, Liron Levin
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110368- (2024)
Summary: Deconvolution algorithms mostly rely on single-cell RNA-sequencing (scRNA-seq) data applied onto bulk RNA-sequencing (bulk RNA-seq) to estimate tissues’ cell-type composition, with performance accuracy validated on deposited databases. Adi
Externí odkaz:
https://doaj.org/article/120ff37dd2ea4aedb2a1d37c407109f6
Autor:
Nataly Makarenkov, Uri Yoel, Yulia Haim, Yair Pincu, Nikhil S. Bhandarkar, Aryeh Shalev, Ilan Shelef, Idit F. Liberty, Gal Ben-Arie, David Yardeni, Assaf Rudich, Ohad Etzion, Isana Veksler-Lublinsky
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 890 (2024)
Circulating miRNAs are increasingly being considered as biomarkers in various medical contexts, but the value of analyzing isomiRs (isoforms of canonical miRNA sequences) has not frequently been assessed. Here we hypothesize that an in-depth analysis
Externí odkaz:
https://doaj.org/article/b903857340fc4cd0985b7a17db647f57
Autor:
Yair Pincu, Uri Yoel, Yulia Haim, Nataly Makarenkov, Nitzan Maixner, Ruthy Shaco-Levy, Nava Bashan, Dror Dicker, Assaf Rudich
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obesity is a heterogenous condition that affects the life and health of patients to different degrees and in different ways. Yet, most approaches to treat obesity are not currently prescribed, at least in a systematic manner, based on individual obes
Externí odkaz:
https://doaj.org/article/cd88a948510c4918a4ec8a488dc8efd8
Autor:
Fabrizio C. Lucchini, Stephan Wueest, Tenagne D. Challa, Flurin Item, Salvatore Modica, Marcela Borsigova, Yulia Haim, Christian Wolfrum, Assaf Rudich, Daniel Konrad
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Understanding the regulatory mechanisms governing brown and beige adipose mediated thermogenesis is of interest in order to develop therapeutic strategies to treat obesity. Here, the authors show that adipocyte-expressed apoptosis signal-regulating k
Externí odkaz:
https://doaj.org/article/a5f0fcf02ab1420cbe65f5ab4e73cc5e
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 535-541 (2020)
Increasing energy expenditure via induction of browning in white adipose tissue has emerged as a potential strategy to treat obesity and associated metabolic complications. We previously reported that ASK1 inhibition in adipocytes protected from high
Externí odkaz:
https://doaj.org/article/0d43f3fd018043709c85663053d6a064
Autor:
Nikhil S. Bhandarkar, Rotem Lahav, Nitzan Maixner, Yulia Haim, G. William Wong, Assaf Rudich, Uri Yoel
Publikováno v:
Physiological Reports, Vol 9, Iss 18, Pp n/a-n/a (2021)
Abstract In humans, exercise‐induced thermogenesis is a markedly variable component of total energy expenditure, which had been acutely affected worldwide by COVID‐19 pandemic‐related lockdowns. We hypothesized that dietary macronutrient compos
Externí odkaz:
https://doaj.org/article/dec19c05b81a4ec99b18049e4d7b58cf
Autor:
Nitzan Maixner, Yulia Haim, Matthias Blüher, Vered Chalifa-Caspi, Isana Veksler-Lublinsky, Nataly Makarenkov, Uri Yoel, Nava Bashan, Idit F. Liberty, Ivan Kukeev, Oleg Dukhno, Dan Levy, Assaf Rudich
Publikováno v:
Cells, Vol 11, Iss 19, p 3046 (2022)
Objective: Up-regulated expression of transcription-factor E2F1 in human visceral adipose tissue (VAT) characterizes a dysmetabolic obesity sub-phenotype. An E2F1-miRNA network has been described in multiple cancers. Here we investigated whether elev
Externí odkaz:
https://doaj.org/article/b7c7f7c5abb64bbfb1bccaf79968ec5a
Autor:
Nir Goldstein, Yulia Haim, Pamela Mattar, Sapir Hadadi-Bechor, Nitzan Maixner, Peter Kovacs, Matthias Blüher, Assaf Rudich
Publikováno v:
Adipocyte, Vol 8, Iss 1, Pp 51-60 (2019)
Obesity, a condition most commonly associated with hyper-leptinemia, is also characterized by increased expression of autophagy genes and likely autophagic activity in human adipose tissue (AT). Indeed, circulating leptin levels were previously shown
Externí odkaz:
https://doaj.org/article/7504f862a8044f4a8d5db64dafc39620
Autor:
Yulia Haim, Matthias Blüher, Daniel Konrad, Nir Goldstein, Nora Klöting, Ilana Harman-Boehm, Boris Kirshtein, Doron Ginsberg, Tanya Tarnovscki, Yftach Gepner, Iris Shai, Assaf Rudich
Publikováno v:
Molecular Metabolism, Vol 6, Iss 7, Pp 725-736 (2017)
Objective: Obesity variably disrupts human health, but molecular-based patients' health-risk stratification is limited. Adipose tissue (AT) stresses may link obesity with metabolic dysfunction, but how they signal in humans remains poorly-characteriz
Externí odkaz:
https://doaj.org/article/a6e72e1ef48b40659e43d1e99c48e107
Autor:
Nir Goldstein, Yarden Kezerle, Yftach Gepner, Yulia Haim, Tal Pecht, Roi Gazit, Vera Polischuk, Idit F. Liberty, Boris Kirshtein, Ruthy Shaco-Levy, Matthias Blüher, Assaf Rudich
Publikováno v:
Cells, Vol 9, Iss 6, p 1508 (2020)
The identification of human obesity sub-types may improve the clinical management of patients with obesity and uncover previously unrecognized obesity mechanisms. Here, we hypothesized that adipose tissue (AT) mast cells (MC) estimation could be a ma
Externí odkaz:
https://doaj.org/article/46e27ae48cf3463c8a26f5e0f1995839