Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Yulia Epshtein"'
Publikováno v:
Cells, Vol 12, Iss 19, p 2405 (2023)
GADD45a is a gene we previously reported as a mediator of responses to acute lung injury. GADD45a−/− mice express decreased Akt and increased Akt ubiquitination due to the reduced expression of UCHL1 (ubiquitin c-terminal hydrolase L1), a deubiqu
Externí odkaz:
https://doaj.org/article/cc7629dd72504c6eb730d3d408293d4b
Autor:
Panfeng Fu, Yulia Epshtein, Ramaswamy Ramchandran, Joseph B. Mascarenhas, Anne E. Cress, Jeffrey Jacobson, Joe G. N. Garcia, Viswanathan Natarajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract We have shown that both reactive oxygen species (ROS) and paxillin tyrosine phosphorylation regulate LPS-induced human lung endothelial permeability. Mitochondrial ROS (mtROS) is known to increase endothelial cell (EC) permeability which req
Externí odkaz:
https://doaj.org/article/1ec0f4a987774551a8f0d88321e35000
Autor:
Weiguo Chen, Jamie M. C. Gard, Yulia Epshtein, Sara M. Camp, Joe G. N. Garcia, Jeffrey R. Jacobson, Anne E. Cress
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
We previously reported integrin beta 4 (ITGB4) is an important mediator of lung vascular protection by simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A-reductase inhibitor. In this study, we report increased endothelial cell (EC) expression speci
Externí odkaz:
https://doaj.org/article/e0971b32a5dd486899a2d375875b9e94
Publikováno v:
Cells, Vol 10, Iss 9, p 2186 (2021)
We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS). Recently, it has been reported that haloperidol, an antipsychotic
Externí odkaz:
https://doaj.org/article/b4fe4d063ecd478a869f0676c2211547
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 11, Iss 19, Pp 131-137 (2014)
We have shown earlier that Kir2 channels are suppressed by the elevation of membrane cholesterol. Moreover, it is also well known that activation of Kir channels is critically dependent on a regulatory phospholipid, phosphatidylinositol-4,5-bisphosph
Externí odkaz:
https://doaj.org/article/83507930d0da4ef3b138b0a4b84c074a
Autor:
Yulia Epshtein, Ramaswamy Ramchandran, Anne E. Cress, Jeffrey R. Jacobson, Panfeng Fu, Joe G.N. Garcia, Joseph B Mascarenhas, Viswanathan Natarajan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
We have shown that both reactive oxygen species (ROS) and paxillin tyrosine phosphorylation regulate LPS-induced human lung endothelial permeability. Mitochondrial ROS (mtROS) is known to increase endothelial cell (EC) permeability which requires dyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31752cd14c5c4b461bae1846d33641a
https://doaj.org/article/1ec0f4a987774551a8f0d88321e35000
https://doaj.org/article/1ec0f4a987774551a8f0d88321e35000
Autor:
Yulia Epshtein, Saad Sammani, Ankit A. Desai, Mounica Bandela, Hector Quijada, Joe G.N. Garcia, Sumegha Mitra, Jeffrey R. Jacobson, Weiguo Chen
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Increasing evidence suggests an important role for deubiquitinating enzymes (DUBs) in modulating a variety of biological functions and diseases. We previously identified the upregulation of the DUB ubiquitin carboxyl terminal hydrolase 1 (UCHL1) in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea0668c6d14d2dd3f56713a5004658d
https://doi.org/10.1152/ajplung.00492.2020
https://doi.org/10.1152/ajplung.00492.2020
Autor:
Luisa Rezende, Natalia Fernanda Do Couto, Weslley Fernandes-Braga, Yulia Epshtein, Jacqueline Isaura Alvarez-Leite, Irena Levitan, Luciana de Oliveira Andrade
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1864(9)
Cholesterol sequestration from plasma membrane has been shown to induce lipid packing disruption, causing actin cytoskeleton reorganization and polymerization, increasing cell stiffness and inducing lysosomal exocytosis in non-professional phagocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c099a6155aad51e8e6ab6e7ccd97caf
https://pubmed.ncbi.nlm.nih.gov/35504320
https://pubmed.ncbi.nlm.nih.gov/35504320
Publikováno v:
Cells
Cells; Volume 10; Issue 9; Pages: 2186
Cells, Vol 10, Iss 2186, p 2186 (2021)
Cells; Volume 10; Issue 9; Pages: 2186
Cells, Vol 10, Iss 2186, p 2186 (2021)
We previously reported that claudin-5, a tight junctional protein, mediates lung vascular permeability in a murine model of acute lung injury (ALI) induced by lipopolysaccharide (LPS). Recently, it has been reported that haloperidol, an antipsychotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329dee2992989e47e9b34627ce932d93
https://pubmed.ncbi.nlm.nih.gov/34571834
https://pubmed.ncbi.nlm.nih.gov/34571834
Publikováno v:
TP113. TP113 ACUTE LUNG INJURY AND REPAIR.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3d83c29ad8ac3ea47e473401c07e983
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4369
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4369