Výsledky vyhledávání - "Yulia Aleksandrovna Kuzovkova"

Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors

Autor: Yulia Aleksandrovna Kuzovkova, Sergey Maliarchouk, Ilya Okun, Konstantin V. Balakin, Volodymyr M. Kysil, Alexandre V. Ivachtchenko, Sergey E. Tkachenko, Dmitri V. Kravchenko

Publikováno v: Journal of medicinal chemistry. 48(11)

Synthesis, biological evaluation, and SAR dependencies for a series of novel 1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinoline inhibitors of caspase-3 are described. The inhibitory activity of the synthesized compounds is highly dependent on the natur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8464791e6e23b76667a389a0df55791
https://pubmed.ncbi.nlm.nih.gov/15916416

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání