Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yulia Aleksandrova"'
Autor:
Ruiwen Zhao, Olga Sukocheva, Edmund Tse, Margarita Neganova, Yulia Aleksandrova, Yufei Zheng, Hao Gu, Deyao Zhao, SabbaRao V. Madhunapantula, Xiaorong Zhu, Junqi Liu, Ruitai Fan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Copper is an important metal micronutrient, required for the balanced growth and normal physiological functions of human organism. Copper-related toxicity and dysbalanced metabolism were associated with the disruption of intracellular respir
Externí odkaz:
https://doaj.org/article/8c24b26347dd4ae4a926af85aedade29
Autor:
Olga A. Sukocheva, Margarita E. Neganova, Yulia Aleksandrova, Jack T. Burcher, Elena Chugunova, Ruitai Fan, Edmund Tse, Gautam Sethi, Anupam Bishayee, Junqi Liu
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-40 (2024)
Abstract Anticancer immune surveillance and immunotherapies trigger activation of cytotoxic cytokine signaling, including tumor necrosis factor-α (TNF-α) and TNF-related apoptosis-inducing ligand (TRAIL) pathways. The pro-inflammatory cytokine TNF-
Externí odkaz:
https://doaj.org/article/3f34fcd20ba7425ab38ab6412822252b
Autor:
Andrey Smolobochkin, Dinara Niyazova, Almir Gazizov, Marat Syzdykbayev, Alexandra Voloshina, Syumbelya Amerhanova, Anna Lyubina, Margarita Neganova, Yulia Aleksandrova, Olga Babaeva, Julia Voronina, Nurbol Appazov, Oleg Sinyashin, Igor Alabugin, Alexander Burilov, Michail Pudovik
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6724 (2024)
A family of bifunctional dihetarylmethanes and dibenzoxanthenes is assembled via a reaction of acetals containing a 2-chloroacetamide moiety with phenols and related oxygen-containing heterocycles. These compounds demonstrated selective antitumor act
Externí odkaz:
https://doaj.org/article/1211386e6f274ea8af25c194fc085637
Autor:
Deyao Zhao, Yingyi Mo, Margarita E. Neganova, Yulia Aleksandrova, Edmund Tse, Vladimir N. Chubarev, Ruitai Fan, Olga A. Sukocheva, Junqi Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Successful clinical methods for tumor elimination include a combination of surgical resection, radiotherapy, and chemotherapy. Radiotherapy is one of the crucial components of the cancer treatment regimens which allow to extend patient life expectanc
Externí odkaz:
https://doaj.org/article/b2f2e74a328e49e89cb876f164290852
Autor:
Evgenia Subakaeva, Pavel Zelenikhin, Evgenia Sokolova, Arina Pergat, Yulia Aleksandrova, Dmitriy Shurpik, Ivan Stoikov
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2660 (2023)
The growing problem of bacterial resistance to antimicrobials actualizes the development of new approaches to solve this challenge. Supramolecular chemistry tools can overcome the limited bacterial resistance and side effects of classical sulfonamide
Externí odkaz:
https://doaj.org/article/f57a467a21ab4d9d8dd9e92304a8f26a
Autor:
Yulia Aleksandrova, Aldar Munkuev, Evgenii Mozhaitsev, Evgeniy Suslov, Konstantin Volcho, Nariman Salakhutdinov, Margarita Neganova
Publikováno v:
Cancers, Vol 15, Iss 20, p 4985 (2023)
Multidrug resistance is the dominant obstacle to effective chemotherapy for malignant neoplasms. It is well known that neoplastic cells use a wide range of adaptive mechanisms to form and maintain resistance against antitumor agents, which makes it u
Externí odkaz:
https://doaj.org/article/5a3ffb9e66c84da08a048d0d34c78228
Autor:
Yulia Aleksandrova, Margarita Neganova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14766 (2023)
The relationship between oncological pathologies and neurodegenerative disorders is extremely complex and is a topic of concern among a growing number of researchers around the world. In recent years, convincing scientific evidence has accumulated th
Externí odkaz:
https://doaj.org/article/d3de61e56dd34cdfbac5944680118f28
Autor:
Elmira Gibadullina, Margarita Neganova, Yulia Aleksandrova, Hoang Bao Tran Nguyen, Alexandra Voloshina, Mikhail Khrizanforov, Thi Thu Nguyen, Ekaterina Vinyukova, Konstantin Volcho, Dmitry Tsypyshev, Anna Lyubina, Syumbelya Amerhanova, Anna Strelnik, Julia Voronina, Daut Islamov, Rakhmetulla Zhapparbergenov, Nurbol Appazov, Beauty Chabuka, Kimberley Christopher, Alexander Burilov, Nariman Salakhutdinov, Oleg Sinyashin, Igor Alabugin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12637 (2023)
The utility of sterically hindered phenols (SHPs) in drug design is based on their chameleonic ability to switch from an antioxidant that can protect healthy tissues to highly cytotoxic species that can target tumor cells. This work explores the biol
Externí odkaz:
https://doaj.org/article/1071746952fa40ceb533c9ed9f0a574a
Autor:
Yulia Aleksandrova, Aldar Munkuev, Evgenii Mozhaitsev, Evgenii Suslov, Dmitry Tsypyshev, Kirill Chaprov, Roman Begunov, Konstantin Volcho, Nariman Salakhutdinov, Margarita Neganova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9743 (2023)
Novel monoterpene-based hydroxamic acids of two structural types were synthesized for the first time. The first type consisted of compounds with a hydroxamate group directly bound to acyclic, monocyclic and bicyclic monoterpene scaffolds. The second
Externí odkaz:
https://doaj.org/article/5a6ee81fa940424db659a0af1b6a9b93
Autor:
Yulia Aleksandrova, Kirill Chaprov, Alexandra Podturkina, Oleg Ardashov, Ekaterina Yandulova, Konstantin Volcho, Nariman Salakhutdinov, Margarita Neganova
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5842 (2023)
Parkinson’s disease is the second most common neurodegenerative disease. Unfortunately, there is still no definitive disease-modifying therapy. In our work, the antiparkinsonian potential of trans-epoxide (1S,2S,3R,4S,6R)-1-methyl-4-(prop-1-en-2-yl
Externí odkaz:
https://doaj.org/article/88b7955197d2449ca9111be49f214f3c