Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yulia A. Pelogeykina"'
Publikováno v:
Open Journal of Molecular and Integrative Physiology. :1-7
The adipocytokine apelin is capable to reduce myocardial ischemia/reperfusion injury in rodents. Cardioprotective activity of apelin may be attributed to upregulation of endothelial nitric oxide synthase (eNOS). This study was designed to examine met
Publikováno v:
Health. :927-934
This work was designed to explore efficacy of apelin-12 (A-12) as a cardioprotective agent when given before ischemia or at reperfusion using the isolated working heart model. Hearts of male Wistar rats were subjected to 30-min stabilization period f
Autor:
Irina Studneva, Oleg I. Pisarenko, Yulia A. Pelogeykina, Shul'zhenko Vs, L. I. Serebryakova, Oxana M. Veselova
Publikováno v:
Peptides. 73
Exogenously administered chemically modified apelin-12 (MA) has been shown to exhibit protective effects in myocardial ischemia/reperfusion (I/R) injury. They include reduction of ROS formation, cell death and cardiometabolic abnormalities. The aim o
Autor:
Alexander Timoshin, Philippe Valet, Oleg I. Pisarenko, Rodica Anesia, Angelo Parini, Oksana Kunduzova, Irina Studneva, Shul'zhenko Vs, Yulia A. Pelogeykina
Publikováno v:
British Journal of Pharmacology
Background and Purpose Mitochondria-derived oxidative stress is believed to be crucially involved in cardiac ischaemia reperfusion (I/R) injury, although currently no therapies exist that specifically target mitochondrial reactive oxygen species (ROS
Publikováno v:
The Journal of surgical research. 194(1)
C-terminal fragments of adipokine apelin are able to attenuate myocardial ischemia-reperfusion (I/R) injury, but whether their effects are manifested during cardioplegic arrest remain obscure. This study was designed to evaluate the efficacy of natur
Autor:
A. S. Molokoedov, Maria E Pal'keeva, L. I. Serebryakova, Tskitishvili Ov, Andrei A Az'muko, Zhanna D. Bespalova, Denis N. Khatri, Oleg I. Pisarenko, Irina Studneva, Maria Sidorova, Yulia A. Pelogeykina
Publikováno v:
Journal of Pharmacology & Pharmacotherapeutics
Objective: To examine cardioprotective effects of Ρ-terminal fragment of adipokine apelin-12 (A12), its novel structural analogue [MeArg 1 , NLe 10 ]-A12 (I), and [d-Ala 12 ]-A12 (II), a putative antagonist of APJ receptor, employing in vivo model o