Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Yulia A. Medvedeva"'
Autor:
Céline Barlier, Diego Barriales, Alexey Samosyuk, Sascha Jung, Srikanth Ravichandran, Yulia A. Medvedeva, Juan Anguita, Antonio del Sol
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-9 (2021)
Abstract Immunomodulation strategies are crucial for several biomedical applications. However, the immune system is highly heterogeneous and its functional responses to infections remains elusive. Indeed, the characterization of immune response parti
Externí odkaz:
https://doaj.org/article/c7f2cf9941e44be6a03cff557f5065c5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8591 (2023)
Differential methylation (DM) is actively recruited in different types of fundamental and translational studies. Currently, microarray- and NGS-based approaches for methylation analysis are the most widely used with multiple statistical models design
Externí odkaz:
https://doaj.org/article/b68e9a5e36d34749aff885cd70951bf4
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6229 (2023)
Single-cell RNA-seq data contains a lot of dropouts hampering downstream analyses due to the low number and inefficient capture of mRNAs in individual cells. Here, we present Epi-Impute, a computational method for dropout imputation by reconciling ex
Externí odkaz:
https://doaj.org/article/df91d16a64bf4cbda6f0037133cd7d16
Autor:
Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J. F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Mammalian genomes encode tens of thousands of ncRNAs that have important roles in regulation of gene expression and chromatin organization. Here, the authors present RADICLseq to map RNA-chromatin interactions in intact nuclei to shed light on these
Externí odkaz:
https://doaj.org/article/3ee35708eeee438bbb6649cdd0169ea5
Autor:
Ekaterina I. Romanova, Anatoliy V. Zubritskiy, Anna V. Lioznova, Adewale J. Ogunleye, Vasily A. Golotin, Anna A. Guts, Andreas Lennartsson, Oleg N. Demidov, Yulia A. Medvedeva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11413 (2022)
Acute myeloid leukemia (AML) is a rapidly progressing heterogeneous disease with a high mortality rate, which is characterized by hyperproliferation of atypical immature myeloid cells. The number of AML patients is expected to increase in the near fu
Externí odkaz:
https://doaj.org/article/845226ab7741478e8614482d364fd577
Publikováno v:
F1000Research, Vol 10 (2021)
Emerging studies demonstrate the ability of microRNAs (miRNAs) to activate genes via different mechanisms. Specifically, miRNAs may trigger an enhancer promoting chromatin remodelling in the enhancer region, thus activating the enhancer and its targe
Externí odkaz:
https://doaj.org/article/dc39439f9daa4faaab58f8f1cec62ade
Publikováno v:
F1000Research, Vol 10 (2021)
Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by genetic and epigenetic aberrations that alter the differentiation capacity of myeloid progenitor cells. The transcription factor CEBPα is frequently mutated in A
Externí odkaz:
https://doaj.org/article/6b67a564551f40819869c11fcaf11249
Autor:
Anna V. Lioznova, Abdullah M. Khamis, Artem V. Artemov, Elizaveta Besedina, Vasily Ramensky, Vladimir B. Bajic, Ivan V. Kulakovskiy, Yulia A. Medvedeva
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background DNA methylation is involved in the regulation of gene expression. Although bisulfite-sequencing based methods profile DNA methylation at a single CpG resolution, methylation levels are usually averaged over genomic regions in the
Externí odkaz:
https://doaj.org/article/a97146a5224449c9b11c9d3fc525017e
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 18 (2022)
Long non-coding RNAs (lncRNAs) play an important role in genome regulation. Specifically, many lncRNAs interact with chromatin, recruit epigenetic complexes and in this way affect large-scale gene expression programs. However, the experimental data a
Externí odkaz:
https://doaj.org/article/fd06f5f9817442a1aaccf6362a271f5e
Autor:
Alessandro Bonetti, Federico Agostini, Ana Maria Suzuki, Kosuke Hashimoto, Giovanni Pascarella, Juliette Gimenez, Leonie Roos, Alex J. Nash, Marco Ghilotti, Christopher J. F. Cameron, Matthew Valentine, Yulia A. Medvedeva, Shuhei Noguchi, Eneritz Agirre, Kaori Kashi, Samudyata, Joachim Luginbühl, Riccardo Cazzoli, Saumya Agrawal, Nicholas M. Luscombe, Mathieu Blanchette, Takeya Kasukawa, Michiel de Hoon, Erik Arner, Boris Lenhard, Charles Plessy, Gonçalo Castelo-Branco, Valerio Orlando, Piero Carninci
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/1c6594919e4a4dec9114c20da2fa808b