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pro vyhledávání: '"Yule, IA"'
The development of antibacterial drugs based on novel chemotypes is essential to the future management of serious drug resistant infections. We herein report the design, synthesis and SAR of a novel series of N-ethylurea inhibitors based on a pyridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::3672803f44eb3d978657f7f6cac7f115
https://eprints.whiterose.ac.uk/84087/3/Eur_J_Med_Chem_PUC_paper_revised_CWGF.pdf
https://eprints.whiterose.ac.uk/84087/3/Eur_J_Med_Chem_PUC_paper_revised_CWGF.pdf
Autor:
Yule, Ian Andrew
The inevitability of bacterial drug resistance to all marketed antibiotic drug classes warrants continual research into the development of novel chemotype antibacterial agents. Drug resistant `superbugs' such as methicillin resistant Staphylococcus a
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.713881
Autor:
Yule IA; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK., Czaplewski LG; Biota Europe Ltd, Begbroke Science Park, Woodstock Road, Begbroke, Oxfordshire OX5 1PF, UK., Pommier S; Biota Europe Ltd, Begbroke Science Park, Woodstock Road, Begbroke, Oxfordshire OX5 1PF, UK., Davies DT; Biota Europe Ltd, Begbroke Science Park, Woodstock Road, Begbroke, Oxfordshire OX5 1PF, UK., Narramore SK; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK., Fishwick CW; School of Chemistry, University of Leeds, Leeds LS2 9JT, UK. Electronic address: C.W.G.Fishwick@leeds.ac.uk.
Publikováno v:
European journal of medicinal chemistry [Eur J Med Chem] 2014 Oct 30; Vol. 86, pp. 31-8. Date of Electronic Publication: 2014 Aug 07.
Autor:
Bedford ST; Vernalis (R&D) Ltd, Granta Park, Cambridge, CB21 6GB, UK., Benwell KR, Brooks T, Chen I, Comer M, Dugdale S, Haymes T, Jordan AM, Kennett GA, Knight AR, Klenke B, LeStrat L, Merrett A, Misra A, Lightowler S, Padfield A, Poullennec K, Reece M, Simmonite H, Wong M, Yule IA
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Oct 15; Vol. 19 (20), pp. 5945-9. Date of Electronic Publication: 2009 Aug 14.
Autor:
Gillespie RJ; Department of Chemistry, Vernalis (R&D) Ltd, 613 Reading Road, Winnersh, Wokingham RG41 5UA, UK., Bamford SJ, Clay A, Gaur S, Haymes T, Jackson PS, Jordan AM, Klenke B, Leonardi S, Liu J, Mansell HL, Ng S, Saadi M, Simmonite H, Stratton GC, Todd RS, Williamson DS, Yule IA
Publikováno v:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2009 Sep 15; Vol. 17 (18), pp. 6590-605. Date of Electronic Publication: 2009 Aug 05.