Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Yulan, Xiong"'
Autor:
Sheila K. Pirooznia, Changqing Yuan, Mohammed Repon Khan, Senthilkumar S. Karuppagounder, Luan Wang, Yulan Xiong, Sung Ung Kang, Yunjong Lee, Valina L. Dawson, Ted M. Dawson
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-21 (2020)
Abstract Background Mutations in PINK1 and parkin cause autosomal recessive Parkinson’s disease (PD). Evidence placing PINK1 and parkin in common pathways regulating multiple aspects of mitochondrial quality control is burgeoning. However, compelli
Externí odkaz:
https://doaj.org/article/8ef5f4a81aad42d5a192413290ae4a4b
Autor:
Milena Fais, Giovanna Sanna, Manuela Galioto, Thi Thanh Duyen Nguyen, Mai Uyên Thi Trần, Paola Sini, Franco Carta, Franco Turrini, Yulan Xiong, Ted M. Dawson, Valina L. Dawson, Claudia Crosio, Ciro Iaccarino
Publikováno v:
Cells, Vol 10, Iss 2, p 203 (2021)
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson’s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of LRRK2 in
Externí odkaz:
https://doaj.org/article/33f04861100e4a389e71c4865bb2ef0a
Autor:
Yulan Xiong, Jianzhong Yu
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder after Alzheimer’s disease. Unfortunately, there is no cure or proven disease modifying therapy for PD. The recent discovery of a number of genes involved
Externí odkaz:
https://doaj.org/article/1207564165924ee8a648322c3861b925
Autor:
Liang Hu, Wyatt Brichalli, Naren Li, Shifan Chen, Yaqing Cheng, Qinfang Liu, Yulan Xiong, Jianzhong Yu
Publikováno v:
EMBO reports. 23
The Hippo pathway is an evolutionarily conserved developmental pathway that controls organ size by integrating diverse regulatory inputs, including actomyosin-mediated cytoskeletal tension. Despite established connections between the actomyosin cytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ccb81c1c96736ef92f0eb84cdd0840
https://doi.org/10.15252/embr.202255851
https://doi.org/10.15252/embr.202255851
Autor:
Yunjong Lee, Sheila K. Pirooznia, Luan Wang, Senthilkumar S. Karuppagounder, Sung Ung Kang, Valina L. Dawson, Changqing Yuan, Mohammed Repon Khan, Yulan Xiong, Ted M. Dawson
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-21 (2020)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Mutations in PINK1 and parkin cause autosomal recessive Parkinson’s disease (PD). Evidence placing PINK1 and parkin in common pathways regulating multiple aspects of mitochondrial quality control is burgeoning. However, compelling eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9264a302919fdf9855357b113f44a30
http://link.springer.com/article/10.1186/s13024-020-00363-x
http://link.springer.com/article/10.1186/s13024-020-00363-x
Autor:
Jungwoo Wren Kim, Yulan Xiong, Stephen M. Eacker, Valina L. Dawson, Xiling Yin, Ted M. Dawson, Ian Martin, Nicholas T. Ingolia
Publikováno v:
eNeuro
Visual Abstract
The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) causes familial Parkinson’s disease (PD) and is also found in a subset of idiopathic cases. Prior studies in Drosophila and human induced pluripotent stem cell (iPSC)-
The G2019S mutation in leucine-rich repeat kinase 2 (LRRK2) causes familial Parkinson’s disease (PD) and is also found in a subset of idiopathic cases. Prior studies in Drosophila and human induced pluripotent stem cell (iPSC)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afe5d40ca2e4c3818c0c18e71e6699
http://europepmc.org/articles/PMC8638676
http://europepmc.org/articles/PMC8638676
Publikováno v:
Sci Signal
Mutations in the kinase LRRK2 and impaired endocytic trafficking are both implicated in the pathogenesis of Parkinson’s disease (PD). Expression of the PD-associated LRRK2 mutant in mouse dopaminergic neurons was shown to disrupt clathrin-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2469c17cf48d3c6da2d837aae6dd9133
https://pubmed.ncbi.nlm.nih.gov/34315807
https://pubmed.ncbi.nlm.nih.gov/34315807
Publikováno v:
Chemical Science. 10:8094-8099
N-Terminal methyltransferase 1 (NTMT1) catalyzes the N-terminal methylation of proteins with a specific N-terminal motif after methionine removal. Aberrant N-terminal methylation has been implicated in several cancers and developmental diseases. Toge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bd2e9bbe29ae64f93e66d06d6d1e2a9
https://doi.org/10.1039/c9sc02550b
https://doi.org/10.1039/c9sc02550b
Autor:
Yulan Xiong, Han Seok Ko, Tae In Kam, Shi Xun Ma, Valina L. Dawson, Sangjune Kim, Raja Sekhar Nirujogi, Ted M. Dawson, Seung-Hwan Kwon, Chan Hyun Na, Sang Ho Kwon, Bo Am Seo, Saurav Brahmachari, Dong-Hoon Kim, Akhilesh Pandey
Publikováno v:
J Proteome Res
Parkinson's disease (PD) is the second most common neurodegenerative disorder that results in motor dysfunction and, eventually, cognitive impairment. α-Synuclein protein is known as a central protein to the pathophysiology of PD, but the underlying
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322ce48a552784b213c777f917641089
https://pubmed.ncbi.nlm.nih.gov/34061533
https://pubmed.ncbi.nlm.nih.gov/34061533
Autor:
Franco Turrini, Paola Sini, Ciro Iaccarino, Valina L. Dawson, Claudia Crosio, Manuela Galioto, Thi Thanh Duyen Nguyen, Franco Carta, Ted M. Dawson, Milena Fais, Mai Uyên Thi Trần, Giovanna Sanna, Yulan Xiong
Publikováno v:
Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 203, p 203 (2021)
Volume 10
Issue 2
Cells, Vol 10, Iss 203, p 203 (2021)
Mutations in LRRK2 play a critical role in both familial and sporadic Parkinson&rsquo
s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of
s disease (PD). Up to date, the role of LRRK2 in PD onset and progression remains largely unknown. However, experimental evidence highlights a critical role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e13e7780bf832b13fa21f9291d7ed2
http://hdl.handle.net/2318/1785482
http://hdl.handle.net/2318/1785482
