Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yukuang, Guo"'
Autor:
Yukuang Guo, MS, Hyunwoo Lee, PhD, Emmanuel Edusei, BS, Shady Albakry, BS, Hyunyoung Jeong, PhD, John Richard Lee, MD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e601 (2020)
Externí odkaz:
https://doaj.org/article/ba8db3268f0548bba75182f411e082d1
Publikováno v:
Drug Metabolism and Disposition. 50:716-724
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb06d9fb461ceb6a740325f61048c012
https://doi.org/10.1124/dmd.122.000832
https://doi.org/10.1124/dmd.122.000832
Autor:
Yukuang Guo, Shaofei Ji, Wei Wang, Susan Wong, Chun-Wan Yen, Chloe Hu, Dennis H. Leung, Emile Plise, Shu Zhang, Chenghong Zhang, Uchenna A. Anene, Donglu Zhang, Christian N. Cunningham, S. Cyrus Khojasteh, Dian Su
Publikováno v:
Analytical Chemistry. 94:2032-2041
Macrocyclic peptides (MCPs) are an emerging class of promising drug modalities that can be used to interrogate hard-to-drug ("undruggable") targets. However, their poor intestinal stability is one of the major liabilities or obstacles for oral drug d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60cbd97bca40f90f04343294eb79b0cb
https://doi.org/10.1021/acs.analchem.1c04008
https://doi.org/10.1021/acs.analchem.1c04008
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 50(5)
Glucuronidation is the most common phase II metabolic pathway to eliminate small molecule drugs from the body. However, determination of glucuronide structure is quite challenging by mass spectrometry due to its inability to generate structure-inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6a26e67d42880ab14b350fa4ff36973
https://pubmed.ncbi.nlm.nih.gov/35241454
https://pubmed.ncbi.nlm.nih.gov/35241454
Publikováno v:
Progress in molecular biology and translational science. 171
Gut bacteria are predominant microorganisms in the gut microbiota and have been recognized to mediate a variety of biotransformations of xenobiotic compounds in the gut. This review is focused on one of the gut bacterial xenobiotic metabolisms, reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2836076cec3bb365c106f616a17ba398
https://pubmed.ncbi.nlm.nih.gov/32475528
https://pubmed.ncbi.nlm.nih.gov/32475528
Gut bacteria are predominant microorganisms in the gut microbiota and have been recognized to mediate a variety of biotransformations of xenobiotic compounds in the gut. This review is focused on one of the gut bacterial xenobiotic metabolisms, reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15f60fa15b2057e29fa6d79d133f6ffb
https://doi.org/10.1016/bs.pmbts.2020.04.002
https://doi.org/10.1016/bs.pmbts.2020.04.002
Autor:
Hyunyoung Jeong, Xiaotong Yang, Hyunwoo Lee, Kyoung-Jae Won, Camila M. Crnkovic, John R. Lee, Yukuang Guo, Jimmy Orjala
Tacrolimus exhibits low and variable drug exposure after oral dosing, but the contributing factors remain unclear. Based on our recent report showing a positive correlation between fecal abundance ofFaecalibacterium prausnitziiand oral tacrolimus dos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9175b27f878027734bbfbd0b73869df2
Autor:
Kuo-Ching, Mei, Yukuang, Guo, Jie, Bai, Pedro M, Costa, Houmam, Kafa, Andrea, Protti, Robert C, Hider, Khuloud T, Al-Jamal
Publikováno v:
ACS Applied Materials & Interfaces
In this study, we propose an organic solvent-free, one-step mechanochemistry approach to engineer water-dispersible graphene oxide/superparamagnetic iron oxide (GO/SPIOs) hybrids, for biomedical applications. Although mechanochemistry has been propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::629fba539093b76cadb54fa47bb683d6
https://pubmed.ncbi.nlm.nih.gov/26101940
https://pubmed.ncbi.nlm.nih.gov/26101940