Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Yuksel Agca"'
Autor:
Fei Sun, Nourhan Nashat Ali, Daniela Londoño-Vásquez, Constantine A. Simintiras, Huanyu Qiao, M. Sofia Ortega, Yuksel Agca, Masashi Takahashi, Rocío M. Rivera, Andrew M. Kelleher, Peter Sutovsky, Amanda L. Patterson, Ahmed Z. Balboula
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Unlike mild DNA damage exposure, DNA damage repair (DDR) is reported to be ineffective in full-grown mammalian oocytes exposed to moderate or severe DNA damage. The underlying mechanisms of this weakened DDR are unknown. Here, we show that m
Externí odkaz:
https://doaj.org/article/87dfd391b25f4e3e97ba122bfc727589
Autor:
Nadezda Ivanova, Qingfan Liu, Cansu Agca, Yuksel Agca, Earl G. Noble, Shawn Narain Whitehead, David Floyd Cechetto
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Metabolic syndrome, the development of which is associated with high-caloric Western diet (HCD) intake, represent a risk factor for mild cognitive impairment (MCI) and dementia including Alzheimer’s disease (AD) later in life. T
Externí odkaz:
https://doaj.org/article/64a842a192ce4eb99182fe1154546bc7
Autor:
Alexander Levit, Sonny Cheng, Olivia Hough, Qingfan Liu, Yuksel Agca, Cansu Agca, Vladimir Hachinski, Shawn N. Whitehead
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Hypertension is recognized as a risk factor for Alzheimer disease, but the causal link remains undetermined. Although astrocytes and microglia play an important role in maintaining the neurovascular unit, astrocytes and microglia have been understudi
Externí odkaz:
https://doaj.org/article/00c19104ec884a9099fd1f494c73d4f8
Autor:
Nina Weishaupt, Qingfan Liu, Sheojung Shin, Ramandeep Singh, Yuksel Agca, Cansu Agca, Vladimir Hachinski, Shawn Narain Whitehead
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-12 (2018)
Abstract Background Most of the animal models commonly used for preclinical research into Alzheimer’s disease (AD) largely fail to address the pathophysiology, including the impact of known risk factors, of the widely diagnosed sporadic form of the
Externí odkaz:
https://doaj.org/article/e3e5e0f85e0e4a20bd0bb7e0f5d8f769
Autor:
Diana Klakotskaia, Cansu Agca, Rachel A Richardson, Edward G Stopa, Todd R Schachtman, Yuksel Agca
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195469 (2018)
Transgenic rat models of Alzheimer's disease were used to examine differences in memory and brain histology. Double transgenic female rats (APP+PS1) over-expressing human amyloid precursor protein (APP) and presenilin 1 (PS1) and single transgenic ra
Externí odkaz:
https://doaj.org/article/1ac8b47461b74df388734eaf96521b84
Publikováno v:
BioTechniques, Vol 41, Iss 6, Pp 715-719 (2006)
Transgene delivery systems, particularly those involving retroviruses, often result in the integration of multiple copies of the transgene throughout the host genome. Since site-specific silencing of trangenes can occur, it becomes important to ident
Externí odkaz:
https://doaj.org/article/c817a309d6ea49c986dc42f74faaaa52
Autor:
Lining Huang, Ibrahim Jasim, Omar Alkorjia, Cansu Agca, Anna Oksman, Yuksel Agca, Daniel E. Goldberg, James D. Benson, Mahmoud Almasri
Publikováno v:
Analytica Chimica Acta. 1267:341226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37b9cb4295a666a25c68ec7df4188db8
https://doi.org/10.1016/j.aca.2023.341226
https://doi.org/10.1016/j.aca.2023.341226
Autor:
Cansu Agca, Youngkyung Jung, Olivia Hough, Shawn N. Whitehead, Vladimir Hachinski, Yuksel Agca, Brian L. Allman, Andrew Gibson, Alexander Levit
Publikováno v:
Molecular Neurobiology. 58:5014-5030
Neuroinflammation and behavioural inflexibility are both common in late adulthood but far more profound in Alzheimer disease (AD). To investigate the relationship between ageing, AD, neuroinflammation, and behavioural flexibility, male wild-type Fisc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f64d3eacf34785be74ec0e29a58f788
https://doi.org/10.1007/s12035-021-02476-w
https://doi.org/10.1007/s12035-021-02476-w
Publikováno v:
Journal of Vibration Testing and System Dynamics. 4:279-286
Intracytoplasmic sperm injection (ICSI), microinjection of a single spermatozoon into an oocyte, is a routine procedure in assisted reproduction programs. This procedure uses fine control of small bore microinjection needles and precise volume contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d602ecaea7b57618a868a14854dd577c
https://doi.org/10.5890/jvtsd.2020.09.005
https://doi.org/10.5890/jvtsd.2020.09.005
Publikováno v:
Journal of Alzheimer's Disease. 73:529-541
Alzheimer's disease (AD) is one of the most devastating and costly diseases, and prevalence of AD increases with age. Furthermore, females are twice as likely to suffer from AD compared to males. The cessation of reproductive steroid hormone producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a5616279b5105b73e89774ab70c989
https://doi.org/10.3233/jad-190935
https://doi.org/10.3233/jad-190935