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Loss of forebrain BIN1 attenuates hippocampal pathology and neuroinflammation in a tauopathy model.

Autor: Ponnusamy M; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Wang S; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Yuksel M; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Hansen MT; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Blazier DM; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., McMillan JD; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Zhang X; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Dammer EB; Department of Biochemistry, Emory University, Atlanta, GA 30322, USA., Collier L; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA., Thinakaran G; Byrd Alzheimer's Center and Research Institute, University of South Florida, Tampa, FL 33613, USA.; Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2023 Apr 19; Vol. 146 (4), pp. 1561-1579.