Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yuko Yonezawa"'
Autor:
Yuko Yonezawa, Manabu Okumura, Naoki Yoshikawa, Tomomi Iwakiri, Kazuhiro Kitahata, Ryuji Ikeda, Hiroshi Sekiya, Kazuhiko Arimori, Yasuji Arimura
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 44:29-36
Autor:
Yoshiyuki Mizushina, Yoshiaki Okamoto, Yuko Yonezawa, Yosuke Ota, Ryohei Sasaki, Yoko Suzuki, Kazuro Sugimura, Peng Huang, Hiromi Yoshida, Y. Demizu
Publikováno v:
Cancer Science. 99(5):1040-1048
Among the vitamin K (VK) compounds, VK3 exhibits distinct cytotoxic activity in cancer cells and is thought to affect redox cycling; however, the underlying mechanisms remain unclear. Here we demonstrate that VK3 selectively inhibits DNA polymerase (
Autor:
Yoichi Takakusagi, Masatoshi Fujita, Ken ichiro Yanagi, Hiromi Yoshida, Fumio Sugawara, Naoko Imamoto, Toshifumi Takeuchi, Takeshi Mizuno, Yuko Yonezawa, Kengo Sakaguchi, Yoshiyuki Mizushina
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1780:203-213
A human replication initiation protein Cdt1 is a very central player in the cell cycle regulation of DNA replication, and geminin down-regulates Cdt1 function by directly binding to it. It has been demonstrated that Cdt1 hyperfunction resulting from
Autor:
Hiromi Yoshida, Masayuki Nishida, Isoko Kuriyama, Yuko Yonezawa, Yoshiyuki Mizushina, Chisato Ishimaru
Publikováno v:
Lipids. 43:373-382
This paper describes the inhibitory activities of cholesterol derivatives such as cholesterol, sodium cholesteryl sulfate, cholesteryl-5alpha, 6alpha-epoxide, cholesteryl chloride, cholesteryl bromide, and cholesteryl hemisuccinate (compounds 1-6, re
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 8, Iss 12, Pp 1206-1224 (2007)
International Journal of Molecular Sciences, Vol 8, Iss 12, Pp 1206-1224 (2007)
DNA topoisomerases (topos) and DNA polymerases (pols) are involved in many aspects of DNA metabolism such as replication reactions. We found that long chain unsaturated fatty acids such as polyunsaturated fatty acids (PUFA) (i.e., eicosapentaenoic ac
Autor:
Hiromi Yoshida, Ikuo Kato, Fumio Sugawara, Isoko Kuriyama, Toshifumi Takeuchi, Yuko Yonezawa, Chisato Ishimaru, Msasaharu Takemura, Yoshiyuki Mizushina
Publikováno v:
Letters in Drug Design & Discovery. 4:239-245
Publikováno v:
Current Enzyme Inhibition. 3:61-75
Autor:
Ryoji Yamakawa, Koji Yahara, Hiroshi Watanabe, Kenji Masunaga, Miho Miura, Yuko Yonezawa, Fumiyo Hieda, Yasunori Mishima
Publikováno v:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 21(12)
Healthcare workers are exposed to serious infectious diseases via needlestick and sharps injuries. The operating room is a particularly important environment in which the risk for needlestick injuries is increased for surgical doctors. According to n
Autor:
Masaharu Takemura, Yuko Yonezawa, Isoko Kuriyama, Ikuo Kato, Dongchon Kang, Tsuyoshi Muta, Yoshiyuki Mizushina, Hiromi Yoshida, Atsushi Fukuoh
Publikováno v:
Cancer Science. 97:716-723
Coenzyme Q (CoQ) is an isoprenoid quinine that functions as an electron carrier in the mitochondrial respiratory chain in eukaryotes. CoQ having shorter isoprenoid chains, especially CoQ1 and CoQ2, selectively inhibited the in vitro activity of eukar
Autor:
Rumi Nakanishi, Masaharu Takemura, Yuko Yonezawa, Yoshiyuki Mizushina, Hiromi Yoshida, Kengo Sakaguchi, Isoko Kuriyama, Toshiko Satake, Noriko Shimazaki, Kohei Kamiya, Yukinobu Uchiyama, Osamu Koiwai
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 99:100-107
Beta-sitosterol-3-O-beta-D-glucopyranoside (compound 1), a steroidal glycoside isolated from onion (Allium cepa L.) selectively inhibited the activity of mammalian DNA polymerase lambda (pol lambda) in vitro. The compound did not influence the activi