Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Yuko Yamakage"'
Autor:
Hitomi Tsuiji, Himari Ogino, Tomofumi Shigenobu, Takao Kohno, Eisuke Okugawa, Yuko Yamakage, Mitsuharu Hattori, Hisashi Oishi
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
Reelin is a secreted protein that plays versatile roles in neuronal development and function, and hypoactivity of Reelin is implicated in many neuropsychiatric disorders. The strength of Reelin signaling is regulated by proteolytic processing, but it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b150d68d8ddbc8e811d1f5bf32232c26
http://link.springer.com/article/10.1038/s41598-020-61380-w
http://link.springer.com/article/10.1038/s41598-020-61380-w
Autor:
Yuko Yamakage, Hitomi Tsuiji, Takao Kohno, Mitsuharu Hattori, Himari Ogino, Takaomi C. Saido, Takashi Saito
Publikováno v:
Biological and Pharmaceutical Bulletin. 42:354-356
Reelin is a secreted protein that antagonizes the deposition and toxicity of amyloid β peptide (Aβ). Therefore, augmentation of Reelin activity may ameliorate Alzheimer's disease (AD). We have recently reported that a disintegrin and metalloprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6a0ac0bd439ccb7c27a9dd30944e01
https://doi.org/10.1248/bpb.b18-00899
https://doi.org/10.1248/bpb.b18-00899
Autor:
Koji Yamanaka, Masato Koike, Asako Furuya, Ikuyo Inoue, Mari Takeuchi, Hitomi Tsuiji, Mitsuharu Hattori, Seiji Watanabe, Yuko Yamakage
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
TDP-43 is an RNA-binding protein important for many aspects of RNA metabolism. Abnormal accumulation of TDP-43 in the cytoplasm of affected neurons is a pathological hallmark of the neurodegenerative diseases frontotemporal dementia (FTD) and amyotro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff62a2c47f37fd513ee380bd56936ef7
http://link.springer.com/article/10.1038/s41598-017-14966-w
http://link.springer.com/article/10.1038/s41598-017-14966-w
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2043
Reelin is a large secreted protein that is essential for the brain development and function. Reelin is negatively regulated by the specific cleavage by a disintegrin and metalloproteinase with thrombospondin type 1 motifs 3 (ADAMTS-3) which is also s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83581386006f2ff00d98ee3b5b18e223
https://pubmed.ncbi.nlm.nih.gov/31463905
https://pubmed.ncbi.nlm.nih.gov/31463905
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2043
Proteolytic cleavage of the secreted signaling protein Reelin has been suggested to play causative roles in many neuropsychiatric and neurodegenerative disorders. Therefore, characterization of the proteolytic activity against Reelin is important not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::447e3186eaf785508f960af23b6bd93a
https://pubmed.ncbi.nlm.nih.gov/31463906
https://pubmed.ncbi.nlm.nih.gov/31463906
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996971
Reelin is a large secreted protein that is essential for the brain development and function. Reelin is negatively regulated by the specific cleavage by a disintegrin and metalloproteinase with thrombospondin type 1 motifs 3 (ADAMTS-3) which is also s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::864b0c69d87e6ca7e105de2a4d722a4d
https://doi.org/10.1007/978-1-4939-9698-8_8
https://doi.org/10.1007/978-1-4939-9698-8_8
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996971
Proteolytic cleavage of the secreted signaling protein Reelin has been suggested to play causative roles in many neuropsychiatric and neurodegenerative disorders. Therefore, characterization of the proteolytic activity against Reelin is important not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433ac1ecad7e2701309597e38486780e
https://doi.org/10.1007/978-1-4939-9698-8_9
https://doi.org/10.1007/978-1-4939-9698-8_9
Autor:
Yuko, Yamakage, Hitomi, Tsuiji, Takao, Kohno, Himari, Ogino, Takashi, Saito, Takaomi C, Saido, Mitsuharu, Hattori
Publikováno v:
Biologicalpharmaceutical bulletin. 42(3)
Reelin is a secreted protein that antagonizes the deposition and toxicity of amyloid β peptide (Aβ). Therefore, augmentation of Reelin activity may ameliorate Alzheimer's disease (AD). We have recently reported that a disintegrin and metalloprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64b1aa499c2f200935ef7617142f29e4
https://pubmed.ncbi.nlm.nih.gov/30828067
https://pubmed.ncbi.nlm.nih.gov/30828067
Autor:
Shingo Dan, Honoka Okunaga, Kiyomi Hikita, Kenta Matsuoka, Haruka Matsuyama, Yuko Yamakage, Naoki Asao, Tomiyasu Murata, Norio Kaneda, Akifumi Oda, Tomoki Nakayoshi, Kuniki Kato, Yui Motoyama, Hitoshi Tanaka
Publikováno v:
Bioorganic & Medicinal Chemistry. 30:115904
Erypoegin K, an isoflavone isolated from the stem bark of Erythrina poeppigiana, has a single chiral carbon in its structure and exists naturally as a racemic mixture. Our previous study showed (S)-erypoegin K selectively exhibits potent anti-prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf6518a285d1ac6a8bf157e58ecae117
https://doi.org/10.1016/j.bmc.2020.115904
https://doi.org/10.1016/j.bmc.2020.115904
Autor:
Norio Kaneda, Rina Shibata, Saori Yamada, Yuko Yamakage, Tomiyasu Murata, Hitoshi Tanaka, Aya Takeda, Kuniki Kato, Natsuki Hattori, Kiyomi Hikita
Publikováno v:
Journal of natural medicines. 72(1)
Erypoegin K is an isoflavone isolated from the stem bark of Erythrina poeppigiana. It contains a furan group at the A-ring of the core isoflavone structure and can inhibit the activity of glyoxalase I, an enzyme that catalyzes the detoxification of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e39676bbf3b8c274123b988ef0b9781
https://pubmed.ncbi.nlm.nih.gov/29151157
https://pubmed.ncbi.nlm.nih.gov/29151157