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Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor

Autor: Hiroki Kourai, Hidemi Takahashi, John B. Zabriskie, Atsushi Tabata, Yukino Watanabe, Nana Ozaki, Hisashi Ohkuni, Yuko Todome, Kazuto Ohkura, Vincent A. Fischetti, Hideaki Nagamune, Hiroki Ohtsuka

Publikováno v: APMIS. 120:56-71

Ohkuni H, Nagamune H, Ozaki N, Tabata A, Todome Y, Watanabe Y, Takahashi H, Ohkura K, Kourai H, Ohtsuka H, Fischetti VA, Zabriskie JB. Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor. APMIS 2012; 120: 56�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::665ae0e1da9ec1706cb067bde6ff4937
https://doi.org/10.1111/j.1600-0463.2011.02813.x

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Evaluation of the GonoGen II Kit for Rapid Identification of Neisseria gonorrhoeae Using Monoclonal Antibody Directed at Gonococcal Outer Membrane Protein 1

Autor: Naoki Tsuruoka, Hisashi Ohkuni, Hiroki Ohtsuka, Yutaka Uzawa, Ken Kikuchi, Yuko Todome

Publikováno v: Journal of the Japanese Association for Infectious Diseases. 82:317-321

The Gonogen II test for rapid identification of Neisseria gonorrhoeae (Gonococcus, GC) was evaluated. The test is based on a colorimetric reaction with monoclonal antibody to GC outer membrane protein 1. Of the 50 clinical isolates of GC, 49 isolates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274b6cecc0d6916b69ec7fee399deb98
https://doi.org/10.11150/kansenshogakuzasshi1970.82.317

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Antibody titers to Streptococus mitis-derived human platelet aggregation factor (Sm-hPAF) in the sera of patients with Kawasaki disease

Autor: Hiroshi Hatakeyama, Hidemi Takahashi, Hideaki Nagamune, Hisashi Ohkuni, Hiroki Ohtsuka, Jun Abe, Yuko Todome

Publikováno v: International Congress Series. 1289:71-74

Serum antibodies reactive with recombinant Sm-hPAF (rSm-hPAF) and synthetic peptide subunits (N-terminal portion of Sm-hPAF) were measured by ELISA in patients with Kawasaki disease (KD) compared with other febrile diseases and healthy subjects (cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6c20b70a328dc0784df04992871740cf
https://doi.org/10.1016/j.ics.2005.11.025

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Pro-Inflammatory Cytokine Release by Human Peripheral Blood Mononuclear Cells under Moderate Hypothermia

Autor: Akio Kimura, Yuko Todome, Naoki Tosaka, Shinsaku Sakurada, Hideyo Tamai, Kiyoshi Kurata, Hisashi Ohkuni

Publikováno v: Nihon Kyukyu Igakukai Zasshi. 10:448-452

近年,重症脳損傷に対するmoderate hypothermia (MH) (32-33℃)の脳保護効果が注目されているが,MH下では白血球の遊走能・貪食能・殺菌能などが抑制されており,それらが易感染性の因子として働�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c73697496157df1a6385aad8a081e2d4
https://doi.org/10.3893/jjaam.10.448

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Streptococcus peroris sp. nov. and Streptococcus infantis sp. nov., new members of the Streptococcus mitis group, isolated from human clinical specimens

Autor: Yoshiaki Kawamura, Xiao-Gang Hou, Sin-Ei Shu, Hisashi Ohkuni, Yuko Todome, Takayuki Ezaki, Kenji Hirose, Ferdousi Sultana

Publikováno v: International Journal of Systematic Bacteriology. 48:921-927

Taxonomic studies were performed on eight strains of alpha-haemolytic streptococci that showed very low DNA-DNA hybridization similarity values with all established members of the mitis group of the genus Streptococcus. These strains were isolated fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff54d13b114f3e5fcd1636dfee42f93
https://doi.org/10.1099/00207713-48-3-921

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Chemotaxis, phagocytosis and killing of monocytes under moderate hypothermia

Autor: Yukino Watanabe, H. Ohkuni, Shinsaku Sakurada, Kiyoshi Kurata, Yuko Todome, Sosuke Kimura, Akio Kimura

Publikováno v: Nihon Kyukyu Igakukai Zasshi. 9:332-335

近年,重症脳傷害に対する中等度低体温(32℃～34℃)の脳保護効果が注目されているが,この療法の際に,しばしば細菌感染症が惹起される。本論文では,この低体温下における単球の機能につ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::724b6d9ff154dfaab163ba8b8b32b6e8
https://doi.org/10.3893/jjaam.9.332

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Purification and partial characterization of a novel human platelet aggregation factor in the extracellular products ofStreptococcus mitis, strain Nm-65

Autor: Nobutaka Ohtani, Shozo Kotani, Toshio Ishikawa, Yuko Todome, Fuminori Okibayashi, Goro Asano, Yukino Watanabe, Hisashi Ohkuni

Publikováno v: FEMS Immunology & Medical Microbiology. 17:121-129

A human blood platelet aggregation factor was purified from the extracellular products (ECP) of Streptococcus mitis, strain Nm-65 by sequential chromatography on DEAE-Sepharose CL-6B, hydroxyapatite and Superdex 75 columns. The purified factor (S. mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d40926482664fb85f631582aa86c5d88
https://doi.org/10.1111/j.1574-695x.1997.tb01004.x

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Superantigenic exotoxin production by isolates of Staphylococcus aureus from the Kawasaki syndrome patients and age-matched control children

Autor: H. Suzuki, K. Harada, F. Okibayashi, S. Sakurai, H. Ohkuni, C. Song, Nobutaka Ohtani, Hideo Igarashi, Manabu Mizuse, Yuko Todome, Shozo Kotani

Publikováno v: Journal of Medical Microbiology. 42:91-95

Surmmary Nineteen strains of Staphylococcus aureus were isolated from the throat or the tooth surfaces of 19 cases amongst 127 patients with Kawasaki syndrome (KS) during the acute phases and 11 S. aureus isolates were obtained from five of 17 diseas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27109e1babf195cbc5cb44cd8e21647
https://doi.org/10.1099/00222615-42-2-91

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The presence of tumor necrosis factor-α and its antibody in the sera of cachexic patients with gastrointestinal cancer

Autor: Norio Matsukura, Takeshi Okuda, Hisashi Ohkuni, Yuko Todome, Akira Tokunaga, Masahiko Onda, Teruo Kiyama, Takashi Mizutani, Itsuo Fujita

Publikováno v: Surgery Today. 24:759-762

Although cancer cachexia has been shown to involve several cytokines, the tumor necrosis factor-alpha (TNF) has rarely been detected in such patients. In this study, sera from 21 patients with cancer cachexia were examined for the presence of TNF and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fa1241367e958ed85a779e91d94886
https://doi.org/10.1007/bf01636787

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Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor

Autor: Hisashi, Ohkuni, Hideaki, Nagamune, Nana, Ozaki, Atsushi, Tabata, Yuko, Todome, Yukino, Watanabe, Hidemi, Takahashi, Kazuto, Ohkura, Hiroki, Kourai, Hiroki, Ohtsuka, Vincent A, Fischetti, John B, Zabriskie

Publikováno v: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 120(1)

We previously purified Streptococcus mitis-derived human platelet aggregation factor (Sm-hPAF) from the culture supernatant of S. mitis strain Nm-65, isolated from the tooth surface of a patient with Kawasaki disease. Here we produced recombinant Sm-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::adccdb024cce7424bff272e03d67877d
https://pubmed.ncbi.nlm.nih.gov/22151309

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