Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Yuko Shirakuni"'
Autor:
Tatsuya Takagi, Masao Nasu, Chizuko Hattori, Steffen Amann, Yuko Shirakuni, Tsugumichi Sato, Carla M. Van Bennekom
Publikováno v:
YAKUGAKU ZASSHI. 135:1161-1168
Thalidomide was approved for the treatment of multiple myeloma in Japan under a risk management program, named TERMS, in 2008. Since then, we have been conducting a survey of the stakeholders to assess the effectiveness of TERMS. These surveys showed
Autor:
Etuko Uejima, Shigeki Inui, Junichi Takahara, Kousuke Okamoto, Yu-Shi Tian, Teruo Yasunaga, Norihito Kawashita, Takanori Ohgaru, Yuko Shirakuni, Hiroyuki Yamasaki, Tatsuya Takagi, Ran Inoue
Publikováno v:
Therapeutic Innovation & Regulatory Science. 47:235-241
This study aimed to determine the potentially severe chemical properties of drugs that can cause adverse drug reactions (ADRs) such as erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) by using a data mini
Publikováno v:
Journal of Computer Aided Chemistry. 10:118-127
The adverse events induced by drugs have been complicated, when two or more drugs are administrated for a patient. We selected "Stevens-Johnson Syndrome (SJS) " as a research object, which is one of the severe skin manifestations. The data source is
Autor:
Rika Nishikiori, Tatsuya Takagi, Yuko Shirakuni, Ryo Shimizu, Kousuke Okamoto, Masaya Kawase, Takanori Ohgaru
Publikováno v:
Journal of Chemical Information and Modeling. 48:207-212
Comparative Molecular Field Analysis (CoMFA) is most widely used as one of the 3-dimensional QSAR (3D-QSAR) methods to identify the relationship between chemical structure and biological activity. Conventional CoMFA requires at least 3 orders of expe
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 32:882-889
We conducted a statistical investigation in which we compared the drug consumption in a new hospice ward with that in other wards. In order to protect the personal information of patients, we used drug consumption data that did not identify individua
Publikováno v:
Biologicalpharmaceutical bulletin. 37(6)
It is thought that both selective serotonin reuptake inhibitors (SSRIs) and non-steroidal anti-inflammatory drugs (NSAIDs) can cause the adverse reaction of upper gastrointestinal hemorrhage (UGIH). To evaluate differences in the probability of UGIH
Autor:
Ryo Shimizu, Takanori Ohgaru, Kousuke Okamoto, Rika Nishikiori, Tatsuya Takagi, Masaya Kawase, Yuko Shirakuni, Norihito Kawashita
Publikováno v:
ChemInform. 39
Conventional comparative molecular field analysis (CoMFA) requires at least 3 orders of experimental data, such as IC50 and Ki, to obtain a good model, although practically there are many screening assays where biological activity is measured only by
Autor:
Tatsuya Takagi, Takanori Ohgaru, Ryo Shimizu, Masaya Kawase, Kousuke Okamoto, Norihito Kawashita, Yuko Shirakuni, Rika Nishikiori
Publikováno v:
Journal of chemical information and modeling. 48(4)
Conventional comparative molecular field analysis (CoMFA) requires at least 3 orders of experimental data, such as IC 50 and K i, to obtain a good model, although practically there are many screening assays where biological activity is measured only
Autor:
Takanori Ohgaru, Ryo Shimizu, Kosuke Okamoto, Norihito Kawashita, Masaya Kawase, Yuko Shirakuni, Rika Nishikiori, Tatsuya Takagi
Publikováno v:
Journal of Chemical Information & Modeling; Mar2008, Vol. 48 Issue 4, p910-917, 8p