Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Yuko Shirahama"'
Autor:
YUKO SHIRAHAMA, KEN YAMAMOTO
Publikováno v:
The Kurume medical journal.
The Polycomb group protein (PcG) SUZ12 forms Polycomb repressive complexes together with histone methyltransferase EZH2. Although the complexes have been demonstrated to be involved in epigenetic maintenance of gene expression in a transcriptional re
Autor:
Kenji Wakai, Hirotaka Matsuo, Keiko Ooyama, Tatsuya Saitoh, Yuko Shirahama, Sahoko Ichihara, Yuichiro Nishida, Rie Ibusuki, Seiko Shimizu, Kokichi Arisawa, Megumi Hara, Keizo Ohnaka, Blanka Stiburkova, Ken Yamamoto, Mitsuhiro Yokota, Mayuko Nakajima, Asahi Hishida, Yuji Hidaka, Hirofumi Nakaoka, Yoichiro Kamatani, Masayuki Sakiyama, Nariyoshi Shinomiya, Hirokazu Uemura, Toshihide Higashino, Akiyoshi Nakayama, Takahiro Nakamura, Masahiro Nakatochi, Mitsuo Nagase, Toshiro Takezaki, Ituro Inoue, Satoko Iwasawa, Mikiya Takao, Keitaro Tanaka, Atsushi Takahashi, Kazuyoshi Hosomichi, Tatsuo Hosoya, Makoto Kawaguchi, Tappei Takada, Yukinori Okada, Hiroshi Nakashima, Michiaki Kubo, Mariko Naito, Tony R. Merriman, Sakurako Katsuura-Kamano, Hiroshi Ooyama, Kimiyoshi Ichida, Yusuke Kawamura, Toru Shimizu, Ippei Shimoshikiryo
Publikováno v:
Annals of the Rheumatic Diseases
ObjectiveThe first ever genome-wide association study (GWAS) of clinically defined gout cases and asymptomatic hyperuricaemia (AHUA) controls was performed to identify novel gout loci that aggravate AHUA into gout.MethodsWe carried out a GWAS of 945
Autor:
M. Osame, Kimiyoshi Arimura, Wataru Matsuyama, Yuko Shirahama, Ikkou Higashimoto, Mikiko Ono, Hideo Mitsuyama
Publikováno v:
Blood. 109:22-30
Churg-Strauss syndrome (CSS) is a systemic disease that shows marked eosinophilia along with eosinophil infiltration in the tissue. Prolonged eosinophil survival plays an important role in the pathogenesis of CSS; however, its detailed molecular mech
Autor:
Hideo Mitsuyama, Kimiyoshi Arimura, Masaki Watanabe, Wataru Matsuyama, Mitsuhiro Osame, Ikkou Higashimoto, Yuko Shirahama
Publikováno v:
The American Journal of Pathology. 168:866-877
Idiopathic pulmonary fibrosis (IPF), characterized by fibroblast proliferation and accumulation of extracellular matrix, including collagen, is a chronic progressive disorder that results in lung remodeling and fibrosis. However, the cellular mechani
Autor:
Mitsuhiro Osame, Sepideh N. Bajestan, Soheila Sharghi-Namini, Yuko Shirahama, Kristjan R. Jessen, Fujio Umehara, Kayoko Itoh, Rhona Mirsky
Publikováno v:
Journal of Neurobiology. 66:243-255
Hedgehog proteins are important in the development of the nervous system. As Desert hedgehog (Dhh) is involved in the development of peripheral nerves and is expressed in adult nerves, it may play a role in the maintenance of adult nerves and degener
Autor:
Yusuke Kawamura, Hirofumi Nakaoka, Akiyoshi Nakayama, Yukinori Okada, Ken Yamamoto, Toshihide Higashino, Masayuki Sakiyama, Toru Shimizu, Hiroshi Ooyama, Keiko Ooyama, Mitsuo Nagase, Yuji Hidaka, Yuko Shirahama, Kazuyoshi Hosomichi, Yuichiro Nishida, Ippei Shimoshikiryo, Asahi Hishida, Sakurako Katsuura-Kamano, Seiko Shimizu, Makoto Kawaguchi
Publikováno v:
Annals of the Rheumatic Diseases; Oct2019, Vol. 78 Issue 10, p1430-1437, 8p, 1 Diagram, 2 Charts, 3 Graphs
Autor:
Ikkou Higashimoto, Kimiyoshi Arimura, Masaki Watanabe, Hideo Mitsuyama, Wataru Matsuyama, Mitsuhiro Osame, Yuko Shirahama
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 33:565-573
The prognosis of sarcoidosis with pulmonary infiltrates differs in each case, and several cytokines are reported to contribute to its deterioration. However, the detailed mechanism has not been fully elucidated. Discoidin domain receptor 1 (DDR1) is
Autor:
Masaki Watanabe, Hideo Mitsuyama, Mitsuhiro Osame, Satoshi Noma, Yuko Shirahama, Ikkou Higashimoto, Kimiyoshi Arimura, Ken-ichi Oonakahara, Wataru Matsuyama
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 178(9)
The chemokine receptor CXCR4, which binds the chemokine stromal cell-derived factor 1, has been reported to be involved in the chemotaxis of inflammatory cells. In addition, AMD3100, an antagonist of CXCR4, has been reported to be an attractive drug
Autor:
Masaki Watanabe, Takashi Wada, Kimiyoshi Arimura, Hideo Mitsuyama, Ikkou Higashimoto, Mitsuhiro Osame, Yuko Shirahama, Wataru Matsuyama
Publikováno v:
Arthritis and rheumatism. 56(2)
金沢大学医学部附属病院血液浄化療法部
Objective. Prolonged survival of eosinophils plays au important role in the pathogenesis of Churg-Strauss syndrome (CSS); however, its detailed molecular mechanism is still unclear. TRAIL an
Objective. Prolonged survival of eosinophils plays au important role in the pathogenesis of Churg-Strauss syndrome (CSS); however, its detailed molecular mechanism is still unclear. TRAIL an
Autor:
Akiyoshi Nakayama, Hirofumi Nakaoka, Ken Yamamoto, Masayuki Sakiyama, Shaukat, Amara, Yu Toyoda, Yukinori Okada, Yoichiro Kamatani, Takahiro Nakamura, Tappei Takada, Katsuhisa Inoue, Tomoya Tomoya, Hiroaki Yuasa, Yuko Shirahama, Hiroshi Nakashima, Seiko Shimizu, Toshihide Higashino, Yusuke Kawamura, Hiraku Ogata, Makoto Kawaguchi
Publikováno v:
Annals of the Rheumatic Diseases; May2017, Vol. 76 Issue 5, p869-877, 9p, 1 Color Photograph, 3 Charts, 2 Graphs, 1 Map