Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yuko Shinagawa"'
Autor:
Fukuda Kenji, Shuichi Kimura, Takashi Nakagawa, Toshihiro Kiguchi, Hiromasa Hashimoto, Yushi Matsuo, Kazuhito Harada, Mariko Maekawa, Soejima Yuki, Masanori Shindo, Masaki Takagi, Mikio Hayashi, Naoki Ogawa, Kazuyuki Hirata, Taku Ikenogami, Yuko Shinagawa, Takeo Katsushima, Mitsuru Takahashi, Teruhiko Inoue
Publikováno v:
ACS Medicinal Chemistry Letters. 2:238-242
Short-acting oral calcilytics, calcium-sensing receptor (CaSR) antagonists, have been considered as alternatives for parathyroid hormone (PTH), an injectable bone anabolic drug used in the treatment of osteoporosis. Previously, we identified aminopro
Autor:
Masanori Shindo, Kazuyuki Hirata, Yuko Shinagawa, Teruhiko Inoue, Yushi Matsuo, Takeo Katsushima, Takashi Nakagawa, Hiromasa Hashimoto
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:3809-3813
Synthesis and structure-activity relationship studies on a new aminopropandiol class of derivatives as calcium-sensing receptor antagonists are described. Modification of the phenolic moiety of a calcilytic compound NPS 2143 led to the identification