Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yuko Nitahara-Kasahara"'
Autor:
Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Kunio Hirai, Yuki Oda, Noriko Snagu-Miyamoto, Yuji Yamanashi, Takashi Okada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
IntroductionDuchenne muscular dystrophy (DMD) is a genetic disorder caused by mutations in the dystrophin-encoding gene that leads to muscle necrosis and degeneration with chronic inflammation during growth, resulting in progressive generalized weakn
Externí odkaz:
https://doaj.org/article/e2a973ee24df45b998f81b57b85e6b1a
Autor:
Masafumi Arakawa, Yuki Sakamoto, Yoshitaka Miyagawa, Chikako Nito, Shiro Takahashi, Yuko Nitahara-Kasahara, Satoshi Suda, Yoshiyuki Yamazaki, Mashito Sakai, Kazumi Kimura, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 333-349 (2023)
Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) hold great promise as a cell source for transplantation into injured tissues to alleviate inflammation. However, the therapeutic efficacy of iMSC transplantation for ischemic stroke
Externí odkaz:
https://doaj.org/article/de77c9267be3494292d9022ead8fa26d
Autor:
Yuko Nitahara-Kasahara, Soya Nakayama, Koichi Kimura, Sho Yamaguchi, Yuko Kakiuchi, Chikako Nito, Masahiro Hayashi, Tomoyuki Nakaishi, Yasuyoshi Ueda, Takashi Okada
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Duchenne muscular dystrophy (DMD) is an incurable genetic disease characterized by degeneration and necrosis of myofibers, chronic inflammation, and progressive muscle weakness resulting in premature mortality. Immunosuppressive m
Externí odkaz:
https://doaj.org/article/c3f1f3dc487f4608aa4c00ce14cd3e31
Autor:
Hiromi Hayashita-Kinoh, Posadas-Herrera Guillermo, Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Hironori Okada, Tomoko Chiyo, Shin’ichi Takeda, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 133-141 (2021)
Duchenne muscular dystrophy (DMD) is a severe congenital disease associated with mutation of the dystrophin gene. Supplementation of dystrophin using recombinant adeno-associated virus (rAAV) has promise as a treatment for DMD, although vector-relate
Externí odkaz:
https://doaj.org/article/931c70404534486fa01bab2533ae4c67
Autor:
Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Yuki Oda, Hiromi Hayashita-Kinoh, Shin’ichi Takeda, Takashi Okada
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Multipotent mesenchymal stromal cells (MSCs) are potentially therapeutic for muscle disease because they can accumulate at the sites of injury and act as immunosuppressants. MSCs are attractive candidates for cell-based strategies
Externí odkaz:
https://doaj.org/article/fdbbd525178b44aaad46af829188224b
Autor:
Yuko Nitahara-Kasahara, Mutsuki Kuraoka, Posadas Herrera Guillermo, Hiromi Hayashita-Kinoh, Yasunobu Maruoka, Aki Nakamura-Takahasi, Koichi Kimura, Shin’ichi Takeda, Takashi Okada
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Duchenne muscular dystrophy (DMD) is an inherited progressive disorder that causes skeletal and cardiac muscle deterioration with chronic inflammation. Dental pulp stem cells (DPSCs) are attractive candidates for cell-based strate
Externí odkaz:
https://doaj.org/article/65358317f4784c63b28e72c0c587a755
Autor:
Yuko Nitahara-Kasahara, Shuji Mizumoto, Yukiko U. Inoue, Shota Saka, Guillermo Posadas-Herrera, Aki Nakamura-Takahashi, Yuki Takahashi, Ayana Hashimoto, Kohei Konishi, Shinji Miyata, Chiaki Masuda, Emi Matsumoto, Yasunobu Maruoka, Takahiro Yoshizawa, Toshiki Tanase, Takayoshi Inoue, Shuhei Yamada, Yoshihiro Nomura, Shin'ichi Takeda, Atsushi Watanabe, Tomoki Kosho, Takashi Okada
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 12 (2021)
Musculocontractural Ehlers-Danlos syndrome (mcEDS) is caused by generalized depletion of dermatan sulfate (DS) due to biallelic pathogenic variants in CHST14 encoding dermatan 4-O-sulfotransferase 1 (D4ST1) (mcEDS-CHST14). Here, we generated mouse mo
Externí odkaz:
https://doaj.org/article/18ac308ec99e4737bca148fc2a47dc8c
Autor:
Yuko Nitahara-Kasahara, Guillermo Posadas-Herrera, Shuji Mizumoto, Aki Nakamura-Takahashi, Yukiko U. Inoue, Takayoshi Inoue, Yoshihiro Nomura, Shin’ichi Takeda, Shuhei Yamada, Tomoki Kosho, Takashi Okada
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Carbohydrate sulfotransferase 14 (CHST14) encodes dermatan 4-O-sulfotransferase 1, a critical enzyme for dermatan sulfate (DS) biosynthesis. Musculocontractural Ehlers-Danlos syndrome (mcEDS) is associated with biallelic pathogenic variants of CHST14
Externí odkaz:
https://doaj.org/article/628c0d523aa044b4b5618df49eddeeef
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 737 (2022)
Regenerative medicine aims to restore human functions by regenerating organs and tissues using stem cells or living tissues for the treatment of organ and tissue defects or dysfunction. Clinical trials investigating the treatment of cerebral infarcti
Externí odkaz:
https://doaj.org/article/d67b5d60fe7a4da28dc9ea3ffdf3f31b
Autor:
Kota Sowa, Chikako Nito, Masataka Nakajima, Satoshi Suda, Yasuhiro Nishiyama, Yuki Sakamoto, Yuko Nitahara-Kasahara, Aki Nakamura-Takahashi, Masayuki Ueda, Kazumi Kimura, Takashi Okada
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 281-290 (2018)
Hepatocyte growth factor (HGF) has neuroprotective effects against ischemia-induced injuries. Dental pulp stem cell (DPSC) transplantation attenuates tissue injury in the brain of rats with post-transient middle cerebral artery occlusion. We sought t
Externí odkaz:
https://doaj.org/article/1a3ab391f59241b8b860929d6858b436