Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yuko Nakazato"'
Publikováno v:
Zoological Science. 17:743-750
Mottled mosaic strains in the silkworm, induced by X-ray irradiation, contain chromosomal fragments carrying the larval body marking genes that are lost occasionally during larval development. In one of the mosaic strains, mottled zebra (Zem), the so
Autor:
Akihiko Takashima, Kazutomo Imahori, Yuko Nakazato, Miyuki Murayama, Hiroshi Takahashi, Kaori Noguchi, Marc Mercken
Publikováno v:
Gene. 197:383-387
We have cloned the rat homologue of the presenilin-2 (PS-2) cDNA. PS-2 is responsible for chromosome 1-linked familial Alzheimer's disease. Sequence analysis predicted that the rat PS-2 encodes a 448 amino acid (aa) protein, and there was a very high
Autor:
Ohoshi Murayama, Toshiyuki Honda, Akihiko Takashima, Naomi Nihonmatsu, Gilles Michel, Miyuki Murayama, Kazuki Sato, Kaori Yasutake, Hiroshi Takahashi, Yuko Nakazato, Shaochuen Song, Marc Mercken
Publikováno v:
Neuroscience Letters. 229:61-64
Presenilin 1 (PS 1) shows missense mutations in most early-onset familial Alzheimer's disease (FAD). Transfection of cDNA for wild type PS 1 into rat pheochromocytoma PC12 cells generated a 47 kDa full-size PS 1 protein, which was processed into a 28
Autor:
Miyuki Murayama, Michio Sato, Yuko Nakazato, Toshiyuki Honda, Hiroshi Takahashi, Marc Mercken, Shouji Tanaka, Akihiko Takashima, Kazuki Sato, Kaori Noguchi, Shunzo Kondo
Publikováno v:
Biochemical and Biophysical Research Communications. 227:423-426
Presenilin 1 (PS 1) is the recently identified gene, located on chromosome 14, of which missense mutations can cause early-onset familial Alzheimer's disease. To understand the normal biological function of presenilin 1, we examined the sub-cellular
Autor:
Miyuki Murayama, Kasutomo Imahori, Yuko Nakazato, Marc Mercken, Kazuki Sato, Toshiyuki Honda, Akihiko Takashima, Hiroshi Takahashi, Kaori Noguchi
Publikováno v:
FEBS letters. 389(3)
The majority of cases of early-onset familial Alzheimer disease are caused by mutations in the recently identified presenilin 1 (PS1) gene, located on chromosome 14. PS1, a 467 amino acid protein, is predicted to be an integral membrane protein conta
Autor:
Marc Mercken, Yuko Nakazato, Miyuki Murayama, Hiroshi Takahashi, Akihiko Takashima, Kazutomo Imahori, Kaori Noguchi
Publikováno v:
Neuroscience letters. 206(2-3)
The rat homologue of the presenilin-1 (PS-1) gene, which is responsible for early-onset familial Alzheimer's disease linked to chromosome 14, was cloned and sequenced. The predicted amino acid sequence showed quite high homology among rat, mouse, and