Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Yuko Nagayasu"'
The role of DPYD and the effects of DPYD suppressor luteolin combined with 5‐FU in pancreatic cancer
Autor:
Hiroyuki Kato, Motonori Sato, Aya Naiki‐Ito, Shingo Inaguma, Makoto Sano, Masayuki Komura, Yuko Nagayasu, Kuang Xiaochen, Akihisa Kato, Yoichi Matsuo, Hideaki Ijichi, Satoru Takahashi
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background Despite advances in the treatment of cancer, pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to the lack of effective therapies. Our previous study showed that Luteolin (Lut), a flavonoid, suppressed pancreatocar
Externí odkaz:
https://doaj.org/article/84b4b5aa58d74562a514aeca0702d8b2
Autor:
Jin-ichi Ito, Yuko Nagayasu, Kuniko Okumura-Noji, Rui Lu, Tomo Nishida, Yutaka Miura, Kiyofumi Asai, Alireza Kheirollah, Seiichi Nakaya, Shinji Yokoyama
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 9, Pp 2020-2027 (2007)
Fibroblast growth factor-1 (FGF-1) is secreted by astrocytes and stimulates apolipoprotein E (apoE)-HDL biogenesis by an autocrine mechanism to help in recovery from brain injury. In apoE-deficient mouse astrocytes, FGF-1 stimulated cholesterol biosy
Externí odkaz:
https://doaj.org/article/a2e75841e85e49c1885e03a542acc077
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 679-686 (2005)
The astrocytes prepared by 1 week secondary culture after 1 month primary culture of rat brain cells (M/W cells) synthesized and secreted apolipoprotein E (apoE) and cholesterol more than the astrocytes prepared by conventional 1 week primary and 1 w
Externí odkaz:
https://doaj.org/article/26dcc6e814dc4fd2b98d32f79a4b78c9
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2269-2276 (2004)
Apolipoprotein A-I (apoA-I) induces the translocation of newly synthesized cholesterol as well as caveolin-1 to the cytosolic lipid-protein particle (CLPP) fraction in astrocytes before its appearance in high density lipoprotein generated in the medi
Externí odkaz:
https://doaj.org/article/d579013d5e754161b77eb42f84477477
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 6, Pp 894-904 (2000)
Helical apolipoproteins interact with cellular surface and generate high density lipoprotein (HDL) by removing phospholipid and cholesterol from cells. We have reported that the HDL is generated by this reaction with the fetal rat astrocytes and meni
Externí odkaz:
https://doaj.org/article/ba9bddf0d8a14ed5af4b8e82341f5bec
Autor:
Satoru Takahashi, Ranchana Yeewa, Taku Naiki, Hiroyuki Kato, Yoshinaga Aoyama, Aya Naiki-Ito, Yuko Nagayasu, Shingo Inaguma, Shugo Suzuki
Publikováno v:
Archives of Toxicology
Non-alcoholic steatohepatitis (NASH) is a recognized risk factor for liver fibrosis and malignancies, and is associated with features of metabolic syndrome, such as obesity and insulin resistance (IR). We previously demonstrated that the disturbance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e7b04716babdbe8686b49348a71887
http://europepmc.org/articles/PMC7655588
http://europepmc.org/articles/PMC7655588
Autor:
Ryosuke Ando, Shugo Suzuki, Keitaro Iida, Noriyasu Kawai, Taku Naiki, Toshiki Etani, Yuko Nagayasu, Satoshi Nozaki, Takashi Nagai, Aya Naiki-Ito, Hiroyuki Kato, Satoru Takahashi, Takahiro Yasui
Publikováno v:
Cancer Science
Luteolin is a natural flavonoid with strong anti–oxidative properties that is reported to have an anti–cancer effect in several malignancies other than bladder cancer. In this study, we describe the effect of luteolin on a human bladder cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cebb6609df321143495143faf49e939
https://doi.org/10.1111/cas.14334
https://doi.org/10.1111/cas.14334
Autor:
Masaya Onishi, Keitaro Iida, Shingo Inaguma, Shugo Suzuki, Satoru Takahashi, Aya Naiki-Ito, Hiroyuki Kato, Takahiro Yasui, Toshiki Etani, Yoriko Yamashita, Yasuhito Tanaka, Taku Naiki, Yuko Nagayasu
Publikováno v:
Carcinogenesis
A need exists for seeking effective treatments for castration-resistant prostate cancer (CRPC) in response to its emergence following androgen deprivation therapy as a major clinical problem. In the present study, we investigated the chemopreventive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92651767d83dafc254120cbb32b2501
http://europepmc.org/articles/PMC7422625
http://europepmc.org/articles/PMC7422625
Autor:
Yoshinaga Aoyama, Aya Naiki-Ito, Kuang Xiaochen, Masayuki Komura, Hiroyuki Kato, Yuko Nagayasu, Shingo Inaguma, Hiroyuki Tsuda, Mamoru Tomita, Yoichi Matsuo, Shuji Takiguchi, Satoru Takahashi
Publikováno v:
Nutrients
Nutrients, Vol 14, Iss 42, p 42 (2022)
Nutrients; Volume 14; Issue 1; Pages: 42
Nutrients, Vol 14, Iss 42, p 42 (2022)
Nutrients; Volume 14; Issue 1; Pages: 42
Non-alcoholic steatohepatitis (NASH) can cause liver cirrhosis and hepatocellular carcinoma (HCC), with cases increasing worldwide. To reduce the incidence of liver cirrhosis and HCC, NASH is targeted for the development of treatments, along with vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858185a42cc00f34c473b84604fc6990
https://pubmed.ncbi.nlm.nih.gov/35010924
https://pubmed.ncbi.nlm.nih.gov/35010924
Autor:
Satoshi Inoue, Shuji Takiguchi, Shingo Inaguma, Akinobu Ota, Kawori Watanabe, Kunio Kasugai, Aya Naiki-Ito, Akira Koshino, Satoru Takahashi, Masayuki Komura, Aya Nagano-Matsuo, Kenju Nakao, Yoshitaka Hosokawa, Hiroyuki Kato, Kenji Kasai, Yuko Nagayasu
Publikováno v:
Virchows Archiv : an international journal of pathology. 479(2)
Colorectal cancer (CRC) is one of the most common gastrointestinal cancers worldwide with high morbidity and mortality rates. The discovery of small molecule anticancer reagents has significantly affected cancer therapy. However, the anticancer effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ae5ed148829852c18d87868dec908
https://pubmed.ncbi.nlm.nih.gov/33638656
https://pubmed.ncbi.nlm.nih.gov/33638656