Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yuko Kokubu"'
Autor:
Yuko Kokubu, Tomoko Nagino, Katsunori Sasa, Tatsuo Oikawa, Katsuya Miyake, Akiko Kume, Mikiko Fukuda, Hiromitsu Fuse, Ryuichi Tozawa, Hidetoshi Sakurai
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 10, Pp 1017-1029 (2019)
Abstract Dysferlinopathy is a progressive muscle disorder that includes limb‐girdle muscular dystrophy type 2B and Miyoshi myopathy (MM). It is caused by mutations in the dysferlin (DYSF) gene, whose function is to reseal the muscular membrane. Tre
Externí odkaz:
https://doaj.org/article/b07e2c3175334def8fbba6cc177a30d7
Autor:
Megumi Kowno, Kanako Watanabe-Susaki, Hisako Ishimine, Shinji Komazaki, Kei Enomoto, Yasuhiro Seki, Ying Ying Wang, Yohei Ishigaki, Naoto Ninomiya, Taka-aki K Noguchi, Yuko Kokubu, Keigoh Ohnishi, Yoshiro Nakajima, Kaoru Kato, Atsushi Intoh, Hitomi Takada, Norio Yamakawa, Pi-Chao Wang, Makoto Asashima, Akira Kurisaki
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e81552 (2014)
BackgroundThe pluripotent state of embryonic stem (ES) cells is controlled by a network of specific transcription factors. Recent studies also suggested the significant contribution of mitochondria on the regulation of pluripotent stem cells. However
Externí odkaz:
https://doaj.org/article/52c23efd6a4e47d5af04501a320884f9
Autor:
Soham Chanda, Marius Wernig, Nan Yang, Thomas C. Südhof, Yi Han Ng, Yuko Kokubu, Justyna A. Janas
Publikováno v:
Stem Cell Reports
Summary The differentiation of pluripotent stem cells can be accomplished by sequential activation of signaling pathways or through transcription factor programming. Multistep differentiation imitates embryonic development to obtain authentic cell ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5ffe09254a2102e45a902d265952c0
https://doi.org/10.1016/j.stemcr.2021.05.017
https://doi.org/10.1016/j.stemcr.2021.05.017
Autor:
Akiko Kume, Tomoko Nagino, Katsunori Sasa, Hidetoshi Sakurai, Katsuya Miyake, Mikiko Fukuda, Ryuichi Tozawa, Tatsuo Oikawa, Yuko Kokubu, Hiromitsu Fuse
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 10, Pp 1017-1029 (2019)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Dysferlinopathy is a progressive muscle disorder that includes limb-girdle muscular dystrophy type 2B and Miyoshi myopathy (MM). It is caused by mutations in the dysferlin (DYSF) gene, whose function is to reseal the muscular membrane. Treatment with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7628d2448d55c740864418d077b3ec33
https://doaj.org/article/b07e2c3175334def8fbba6cc177a30d7
https://doaj.org/article/b07e2c3175334def8fbba6cc177a30d7
Autor:
Akiko Oki, Katsunori Sasa, Hiroyuki Takada, Bunnai Saito, Kazumasa Miyamoto, Tomoko Nagino, Hidetoshi Sakurai, Ryuichi Tozawa, Tatsuo Oikawa, Makoto Miyamoto, Yuko Kokubu, Michiko Tawada, Tomoya Sameshima, Akira Kaieda
Publikováno v:
Journal of Medicinal Chemistry. 62:9175-9187
Dysferlinopathies, which are muscular diseases caused by mutations in the dysferlin gene, remain serious medical problems due to the lack of therapeutic agents. Herein, we report the design, synthesis, and structure-activity relationships of a 2,6-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9111b391e088e8dd74adcaa24e72217
https://doi.org/10.1021/acs.jmedchem.9b01100
https://doi.org/10.1021/acs.jmedchem.9b01100
Autor:
Hiroyuki, Takada, Akira, Kaieda, Michiko, Tawada, Tomoko, Nagino, Katsunori, Sasa, Tatsuo, Oikawa, Akiko, Oki, Tomoya, Sameshima, Kazumasa, Miyamoto, Makoto, Miyamoto, Yuko, Kokubu, Ryuichi, Tozawa, Hidetoshi, Sakurai, Bunnai, Saito
Publikováno v:
Journal of medicinal chemistry. 62(20)
Dysferlinopathies, which are muscular diseases caused by mutations in the dysferlin gene, remain serious medical problems due to the lack of therapeutic agents. Herein, we report the design, synthesis, and structure-activity relationships of a 2,6-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd17d6870974e86fdd2fb0361e89ead6
https://pubmed.ncbi.nlm.nih.gov/31550153
https://pubmed.ncbi.nlm.nih.gov/31550153
Autor:
Masahito Ikawa, Ken-ichi Yagami, Yuki Tsunakawa, Juri Hamada, Satoru Takahashi, Akira Kurisaki, Keigo Asano, Haiyan Li, Tomohiro Ishimaru, Nobuko Akiyama, Miki Shimbo, Junji Ishida, Misuzu Hashimoto, Seiya Mizuno, Hyojung Jeon, Taka Aki K. Noguchi, Hisako Ishimine, Masahiro Shinohara, Mutsumi Yamane, Hiroyasu Mizuno, Taito Ito, Chihiro Ishikawa, Ying Ying Wang, Risa Okada, Naoki Ito, Rui Zhou, Michito Hamada, Akiyoshi Fukamizu, Yuko Kokubu, Yuki Imamura, Nobuaki Yoshida, Takashi Shiga, Masaki Shirakawa, Kazuya Murata, Hiroshi Asahara, Shin'ichi Takeda, Takashi Kudo, Taishin Akiyama, Hiroki Sasanuma, Hironobu Morita, Dai Shiba
Publikováno v:
Experimental Animals
The Japan Aerospace Exploration Agency developed the mouse Habitat Cage Unit (HCU) for installation in the Cell Biology Experiment Facility (CBEF) onboard the Japanese Experimental Module (“Kibo”) on the International Space Station. The CBEF prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68486273e9907e592c8bbdcc1a1dabb7
http://europepmc.org/articles/PMC4873486
http://europepmc.org/articles/PMC4873486
Publikováno v:
Biochemical and Biophysical Research Communications. 463:1218-1224
The pituitary gland is a center of the endocrine system that controls homeostasis in an organism by secreting various hormones. The glandular anterior pituitary consists of five different cell types, each expressing specific hormones. However, their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1375fedef7be50e7931dad68ec8543ef
https://doi.org/10.1016/j.bbrc.2015.06.088
https://doi.org/10.1016/j.bbrc.2015.06.088
Autor:
Takaaki Noguchi, Taka-aki K. Noguchi, Naoto Ninomiya, Yuko Kokubu, Taito Ito, Akira Kurisaki, Pi-Chao Wang
Publikováno v:
Protocol Exchange.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b6bfb1709de5daeea662081226978d
https://doi.org/10.1038/protex.2015.046
https://doi.org/10.1038/protex.2015.046
Autor:
Thomas C. Südhof, Thomas Vierbuchen, Yuko Kokubu, Marius Wernig, Austin Ostermeier, Zhiping P. Pang
Publikováno v:
Nature. 463(7284)
Cellular differentiation and lineage commitment are considered to be robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17a2ecd9a75fe55276cc73bc95c207e
https://pubmed.ncbi.nlm.nih.gov/20436508
https://pubmed.ncbi.nlm.nih.gov/20436508