Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Yuko Kawakami"'
Autor:
Raymond M. Wang, Joshua M. Mesfin, Maria Karkanitsa, Jessica L. Ungerleider, Emma Zelus, Yuxue Zhang, Yu Kawakami, Yuko Kawakami, Toshiaki Kawakami, Karen L. Christman
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Bioactive immunomodulatory biomaterials have shown promise for influencing the immune response to promote tissue repair and regeneration. Macrophages and T cells have been associated with this response; however, other immune cell types have
Externí odkaz:
https://doaj.org/article/53b24f1cb5644213966abab737001f82
Autor:
Tomoaki Ando, Ikuo Takazawa, Zachary T. Spencer, Ryoji Ito, Yoshiaki Tomimori, Zbigniew Mikulski, Kenji Matsumoto, Tohru Ishitani, Lee A. Denson, Yu Kawakami, Yuko Kawakami, Jiro Kitaura, Yashi Ahmed, Toshiaki Kawakami
Publikováno v:
Cells, Vol 13, Iss 11, p 986 (2024)
Crohn’s disease is a chronic, debilitating, inflammatory bowel disease. Here, we report a critical role of phospholipase C-β3 (PLC-β3) in intestinal homeostasis. In PLC-β3-deficient mice, exposure to oral dextran sodium sulfate induced lethality
Externí odkaz:
https://doaj.org/article/4b4c080e7a6f457c9d94b7d7d8bd2086
Autor:
Yuko Kawakami, Miho Kimura, Christella Widjaja, Kazumi Kasakura, Tomoaki Ando, Yu Kawakami, Joshua J. Obar, Toshiaki Kawakami
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
BackgroundMast cells are the major effector cell type for IgE-mediated allergic reactions. Recent studies revealed a role for mast cells in orchestrating the host response to viral infections.ObjectiveWe studied the relationship between FcεRI (high-
Externí odkaz:
https://doaj.org/article/83f844f57edb4479a6817cde381d5320
Autor:
Yu Kawakami, Yasunori Kurosawa, Daniela Oltean, Lisa Yuko Espinosa, Hwan Soo Kim, Ian Lemersal, Yuko Kawakami, Shigeru Okumura, Toshiaki Maruyama, Toshiaki Kawakami
Publikováno v:
Allergology International, Vol 71, Iss 1, Pp 147-149 (2022)
Externí odkaz:
https://doaj.org/article/c290ab25ea5e4252a546c575bb7c4004
Autor:
Xiaoyan Luo, Jingsi Chen, Huan Yang, Xinyue Hu, Martin P. Alphonse, Yingchun Shen, Yuko Kawakami, Xiaoying Zhou, Wei Tu, Toshiaki Kawakami, Mei Wan, Nathan K. Archer, Hua Wang, Peisong Gao
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Allergens have been identified as potential triggers in patients with atopic dermatitis (AD). Patients with AD are highly sensitive to cockroach allergen. The underlying mechanism, however, remains undetermined. Here, we established a cockroach aller
Externí odkaz:
https://doaj.org/article/3ffecfb9422f441fa0797a273922140d
Autor:
Daniel Sidler, Ping Wu, Rana Herro, Meike Claus, Dennis Wolf, Yuko Kawakami, Toshiaki Kawakami, Linda Burkly, Michael Croft
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously
Externí odkaz:
https://doaj.org/article/be41c55c70374481a6ffc5f13f861470
Autor:
Tomoaki Ando, Wenbin Xiao, Peisong Gao, Siavash Namiranian, Kenji Matsumoto, Yoshiaki Tomimori, Hong Hong, Hirotaka Yamashita, Miho Kimura, Jun-ichi Kashiwakura, Tissa R. Hata, Kenji Izuhara, Michael F. Gurish, Axel Roers, Nicholas M. Rafaels, Kathleen C. Barnes, Colin Jamora, Yuko Kawakami, Toshiaki Kawakami
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 366-376 (2014)
Atopic dermatitis (AD) is a chronic inflammatory skin disease. Here, we show that phospholipase C-β3 (PLC-β3)-deficient mice spontaneously develop AD-like skin lesions and more severe allergen-induced dermatitis than wild-type mice. Mast cells were
Externí odkaz:
https://doaj.org/article/ccbc808f921f45c6aa8daab249791e9e
Autor:
Shogo Hamaguchi, Yuko Kawakami, Yoriko Honda, Kana Nemoto, Ayaka Sano, Iyuki Namekata, Hikaru Tanaka
Publikováno v:
Journal of Pharmacological Sciences, Vol 123, Iss 2, Pp 167-175 (2013)
Developmental changes in excitation–contraction mechanisms were examined in the ventricular myocardium from fetal, neonatal, and 1-, 2-, and 4-week-old mice. In isolated tissue, the negative inotropic effect of nifedipine decreased, while that of r
Externí odkaz:
https://doaj.org/article/335560d636c84df28998b0031f5cc6b0
Publikováno v:
Case Reports in Neurology, Vol 4, Iss 1, Pp 38-42 (2012)
We present a case of cerebral embolism associated with a left atrial myxoma that was treated with intravenous thrombolytic therapy. A 79-year-old right-handed man with no history of neurological or psychiatric illnesses was referred to our hospital b
Externí odkaz:
https://doaj.org/article/565a8f759bcb40d7bc90a74d4c73f320
Autor:
Jun-ichi Kashiwakura, Yuko Kawakami, Keisuke Yuki, Dirk M Zajonc, Shunji Hasegawa, Yoshiaki Tomimori, Benjamin Caplan, Hirohisa Saito, Masutaka Furue, Hans C Oettgen, Yoshimichi Okayama, Toshiaki Kawakami
Publikováno v:
Allergology International, Vol 58, Iss 3, Pp 411-419 (2009)
Background: Ag-dependent activation of IgE-bearing mast cells is a critical first step in immediate hypersensitivity and other allergic responses. Recent studies have revealed Ag-independent effects of monoclonal mouse IgE molecules on mast cell surv
Externí odkaz:
https://doaj.org/article/209da1aaf44e41aa9b8a2e5090053abc