Zobrazeno 1 - 10
of 505
pro vyhledávání: '"Yuko Kaneko"'
Publikováno v:
Immunological Medicine, Pp 1-5 (2024)
Elevated liver enzymes are commonly observed among adult-onset Still’s disease (AOSD), but severe acute liver failure is extremely rare. Although severe acute liver failure associated with AOSD poses a life-threatening condition, the appropriate tr
Externí odkaz:
https://doaj.org/article/1e4f7681f0c5433db2b8328296cd726c
Autor:
Nam Cong-Nhat Huynh, Rui Ling, Masatsugu Komagamine, Tianshu Shi, Masayuki Tsukasaki, Kotaro Matsuda, Kazuo Okamoto, Tatsuo Asano, Ryunosuke Muro, Warunee Pluemsakunthai, George Kollias, Yuko Kaneko, Tsutomu Takeuchi, Sakae Tanaka, Noriko Komatsu, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract Background Recent single-cell RNA sequencing (scRNA-seq) analysis revealed the functional heterogeneity and pathogenic cell subsets in immune cells, synovial fibroblasts and bone cells in rheumatoid arthritis (RA). JAK inhibitors which ameli
Externí odkaz:
https://doaj.org/article/ea3736b484c44dd68e91bd945e1b9dbe
Autor:
Jun Inamo, Akari Suzuki, Mahoko Takahashi Ueda, Kensuke Yamaguchi, Hiroshi Nishida, Katsuya Suzuki, Yuko Kaneko, Tsutomu Takeuchi, Hiroaki Hatano, Kazuyoshi Ishigaki, Yasushi Ishihama, Kazuhiko Yamamoto, Yuta Kochi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Alternative splicing events are a major causal mechanism for complex traits, but they have been understudied due to the limitation of short-read sequencing. Here, we generate a full-length isoform annotation of human immune cells from an ind
Externí odkaz:
https://doaj.org/article/101fdd61e5eb484db7b4fe4e81d319d3
Autor:
Jun Kikuchi, Yasushi Kondo, Shuichiro Kojima, Shiho Kasai, Yuma Sakai, Masaru Takeshita, Kazuoto Hiramoto, Shuntaro Saito, Hiroyuki Fukui, Hironari Hanaoka, Katsuya Suzuki, Yuko Kaneko
Publikováno v:
Immunological Medicine, Vol 47, Iss 2, Pp 76-84 (2024)
AbstractThis study aims to elucidate the effectiveness and safety of SARS-CoV-2 mRNA vaccination in patients with systemic lupus erythematosus (SLE). We enrolled uninfected SLE patients who received two vaccine doses (BNT162b2 or mRNA-1273) and histo
Externí odkaz:
https://doaj.org/article/c7b0dde3883a4a02a7606391ec3365fb
Publikováno v:
Immunological Medicine, Pp 1-5 (2024)
AbstractAnti-mitochondrial antibody (AMA)-positive myopathy, a recently identified condition with significant cardiac involvement, poses a serious challenge in treatment consensus due to its extreme rarity. While several studies demonstrate the effic
Externí odkaz:
https://doaj.org/article/cc57939898884e2b9137d965d47ebed0
Autor:
Keisuke Izumi, Kanata Suzuki, Masahiro Hashimoto, Masahiro Jinzaki, Shigeru Ko, Tsutomu Takeuchi, Yuko Kaneko
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The modified total Sharp score (mTSS) is often used as an evaluation index for joint destruction caused by rheumatoid arthritis. In this study, special findings (ankylosis, subluxation, and dislocation) are detected to estimate the efficacy
Externí odkaz:
https://doaj.org/article/95ad1bd09d9c4f47b746ca856badd7d4
Autor:
Noriyasu Seki, Hideto Tsujimoto, Shuhei Tanemura, Shinji Kojima, Fumihiko Miyoshi, Jun Kikuchi, Shuntaro Saito, Mitsuhiro Akiyama, Kunio Sugahara, Keiko Yoshimoto, Yuko Kaneko, Kenji Chiba, Tsutomu Takeuchi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract T peripheral helper (Tph) cells are thought to contribute to extra-follicular B cell activation and play a pathogenic role in autoimmune diseases. However, the role of Tph subsets is not fully elucidated. Here, we investigate the immunologic
Externí odkaz:
https://doaj.org/article/8ddd1a39fa6f4692bca56b92a70671ef
Autor:
Ayano Fukushima‐Nomura, Saeko Takamiyagi, Risa Kakuta, Yoshihiro Ito, Ikuko Hirai, Junichi Umemoto, Hironari Hanaoka, Yuko Kaneko, Keiji Tanese
Publikováno v:
Skin Health and Disease, Vol 4, Iss 2, Pp n/a-n/a (2024)
Abstract Palmoplantar pustulosis (PPP) is a chronic inflammatory skin disorder affecting the palms and soles. In rare cases, severe patients develop acute extra‐palmoplantar lesions often accompanied by arthralgia. Such cases with extensive symptom
Externí odkaz:
https://doaj.org/article/ac61c1a1eb8844f3aff7f943954ddd41
Autor:
Masatsugu Komagamine, Noriko Komatsu, Rui Ling, Kazuo Okamoto, Shi Tianshu, Kotaro Matsuda, Tsutomu Takeuchi, Yuko Kaneko, Hiroshi Takayanagi
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-14 (2023)
Abstract Background The types of bone damage in rheumatoid arthritis (RA) include joint erosion, periarticular osteoporosis, and systemic osteoporosis. Janus kinase (JAK) inhibitors ameliorate inflammation and joint erosion in RA, but their effect on
Externí odkaz:
https://doaj.org/article/d2dde201594e419d8b474911715267a4
Autor:
Marenori Kojima, Katsuya Suzuki, Masaru Takeshita, Masaki Ohyagi, Mana Iizuka, Humitsugu Yamane, Keiko Koga, Taku Kouro, Yoshiaki Kassai, Tomoki Yoshihara, Ryutaro Adachi, Kentarou Hashikami, Yuichiro Ota, Keiko Yoshimoto, Yuko Kaneko, Rimpei Morita, Akihiko Yoshimura, Tsutomu Takeuchi
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract T cells play important roles in autoimmune diseases, but it remains unclear how to optimally manipulate them. We focused on the T cell immunoreceptor with Ig and ITIM domains (TIGIT), a coinhibitory molecule that regulates and is expressed i
Externí odkaz:
https://doaj.org/article/f0cee47f61f749aca6573a414bdab36e