Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Yuko Isazawa"'
Autor:
Masato Nakafuku, Koji Oishi, Keisuke Kuida, Sachiko Kamakura, Yukiko Gotoh, Norihisa Masuyama, Takeshi Yoshimatsu, Yuko Isazawa
Publikováno v:
Developmental Biology. 276:172-184
During development of the mammalian brain, many neural precursor cells (NPCs) undergo apoptosis. The regulation of such cell death, however, is poorly understood. We now show that the survival of mouse embryonic NPCs in vitro was increased by culture
Autor:
Toshiyuki Obata, Yuko Isazawa, Keiji Tanaka, Toshiaki Suzuki, Yoko Ogawara, Shohei Kishishita, Yukiko Gotoh, Norihisa Masuyama
Publikováno v:
Journal of Biological Chemistry. 277:21843-21850
p53 plays a key role in DNA damage-induced apoptosis. Recent studies have reported that the phosphatidylinositol 3-OH-kinase-Akt pathway inhibits p53-mediated transcription and apoptosis, although the underlying mechanisms have yet to be determined.