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Akademický článek

SEM Observation of the Filter after Administration of Blinatumomab: A Possibility of Leakage during Home Administration Using a Portable Infusion Pump

Autor: Megumi Takano, Motoki Inoue, Yuko Ikeda, Hidenori Kage, Tohru Inokawa, Kazuhiko Nakadate, Takeo Yasu, Yasumasa Tsuda, Kazumi Goto

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 6, p 5729 (2023)

Blinatumomab (Blincyto® injection solution) is classified as a bispecific T-cell engaging (BiTE) antibody and is intended for the treatment of relapsed/refractory acute lymphoblastic leukemia. It requires continuous infusion to maintain therapeutic

Externí odkaz: https://doaj.org/article/8db6e099d4b541a0a8a13f6ca464980c

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Akademický článek

γ-oryzanol ameliorates the acute stress induced by behavioral anxiety testing in mice

Autor: Salina Akter, Hiroyuki Sasaki, Yuko Ikeda, Hiroki Miyakawa, Shigenobu Shibata

Publikováno v: Journal of Pharmacological Sciences, Vol 138, Iss 2, Pp 155-159 (2018)

We evaluated the anxiolytic effect of γ-oryzanol (GORZ) and elucidated the molecular mechanisms involved in its inhibition of behavioral test-induced anxiety. Behavioral tests were conducted on day 13, and mice were subjected to 30 min of acute rest

Externí odkaz: https://doaj.org/article/0c89cf149337484c84da8e0b8e89eab3

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Akademický článek

Glucagon and/or IGF-1 Production Regulates Resetting of the Liver Circadian Clock in Response to a Protein or Amino Acid-only Diet

Autor: Yuko Ikeda, Mayo Kamagata, Mizuho Hirao, Shinnosuke Yasuda, Shiho Iwami, Hiroyuki Sasaki, Miku Tsubosaka, Yuta Hattori, Ai Todoh, Konomi Tamura, Kazuto Shiga, Teiji Ohtsu, Shigenobu Shibata

Publikováno v: EBioMedicine, Vol 28, Iss C, Pp 210-224 (2018)

The circadian system controls the behavior and multiple physiological functions. In mammals, the suprachiasmatic nucleus (SCN) acts as the master pacemaker and regulates the circadian clocks of peripheral tissues. The SCN receives information regardi

Externí odkaz: https://doaj.org/article/3db7d05b5cc84897aa1a1c3205df5cd8

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Akademický článek

Potent Effects of Flavonoid Nobiletin on Amplitude, Period, and Phase of the Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblasts.

Autor: Ayako Shinozaki, Kenichiro Misawa, Yuko Ikeda, Atsushi Haraguchi, Mayo Kamagata, Yu Tahara, Shigenobu Shibata

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0170904 (2017)

Flavonoids are natural polyphenols that are widely found in plants. The effects of flavonoids on obesity and numerous diseases such as cancer, diabetes, and Alzheimer's have been well studied. However, little is known about the relationships between

Externí odkaz: https://doaj.org/article/252e7289d6e64080b04e71fa8bf7dbb6

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Development of imaging biomarker for esophageal cancer using intravoxel incoherent motion MRI

Autor: Tetsuro Isozaki, Ryoma Urahama, Gaku Ohira, Yuko Ikeda, Koichi Hayano, Kentaro Murakami, Masaya Uesato, Ryoya Mizumachi, Atsushi Hirata, Shunsuke Imanishi, Takeshi Toyozumi, Toru Tochigi, Hisahiro Matsubara, Yoshihiro Kurata

Publikováno v: Esophagus. 18:844-850

Intravoxel incoherent motion MRI (IVIM-MRI) can quantify micro-perfusion at the capillary level in the tissue. The purpose of this study is to measure tumor perfusion using IVIM-MRI, and evaluate its value as a biomarker to predict prognosis in esoph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed11df46f4b84fd537be50b46e64f6a9
https://doi.org/10.1007/s10388-021-00851-z

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Alkylation of Heteroaryl Chlorides through Homolytic Aromatic Substitution by Alkyl Radicals Derived from Alkyl Formates

Autor: Yuko Ikeda, Eiji Shirakawa, Tomoya Mandai, Kyohei Yonekura

Publikováno v: Chemistry Letters. 50:1006-1010

The alkylation of heteroaryl chlorides through a homolytic aromatic substitution (HAS) mechanism was achieved by the use of alkyl formates as alkylating agents in the presence of a tert-butoxy radi...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cf2bc251456e62edec7a090cd7da8695
https://doi.org/10.1246/cl.210015

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