Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Yuko Horikoshi-Sakuraba"'
Autor:
Takashi Mori, Nobuto Kakuda, Naoki Koyama, Yuko Horikoshi-Sakuraba, Haruyasu Yamaguchi, Jun Tan, Kavon Rezai-Zadeh, Gary W. Arendash, Terrence Town
Publikováno v:
The Journal of biological chemistry. 287(9)
Amyloid precursor protein (APP) proteolysis is essential for production of amyloid-β (Aβ) peptides that form β-amyloid plaques in brains of Alzheimer disease (AD) patients. Recent focus has been directed toward a group of naturally occurring anti-
Autor:
Toshiharu Suzuki, Takeshi Ikeuchi, Hiroyasu Akatsu, Tomoko Konno, Takayuki Yamamoto, Saori Hata, Yukiko Hamada, Tohru Yamamoto, Masahiro Maeda, Tadashi Nakaya, Yuhki Saito, Yuko Horikoshi-Sakuraba, Sam Gandy
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 6, Iss 1, p 76 (2011)
Molecular Neurodegeneration, Vol 6, Iss 1, p 76 (2011)
Background Aggregatable amyloid β-peptide (Aβ) and non-aggregatable p3-Alcα are metabolic products of the γ-secretase cleavage of amyloid β-protein precursor (APP) and Alcadeinα (Alcα), respectively. Familial AD (FAD) -linked mutations in the
Autor:
Saori Hata, Yuko Horikoshi-Sakuraba, Jia Fang, Masahiro Maeda, Toshiharu Suzuki, Yuhki Saito, Tomoko Konno, Hiroyasu Akatsu
Publikováno v:
Alzheimer's & Dementia. 7
Autor:
Takashi Mori, Gary W. Arendash, Jun Tan, Yuko Horikoshi-Sakuraba, Terrence Town, Naoki Koyama
Publikováno v:
Glia.
Alzheimer's disease (AD) is the most common progressive dementia and is pathologically characterized by brain deposition of amyloid-beta (Abeta) peptide as senile plaques. Inflammatory and immune response pathways are chronically activated in AD pati
Autor:
Mark P. Mattson, Mohamed R. Mughal, Frank M. LaFerla, Paul S. Aisen, Nobuhisa Iwata, Fang Hua, Karen Duff, Hyang Sook Hoe, Takaomi C. Saido, William L. Klein, Takako Niikura, Yasuji Matsuoka, S. Sakura Minami, G. William Rebeck, Chiho Hirata-Fukae, Hui Fang Li, Hiroe Tsukagoshi-Nagai, Audrey J. Gray, Katsuyoshi Hamada, Yuko Horikoshi-Sakuraba
Publikováno v:
Brain research. 1216
Epidemiological studies indicate that women have a higher risk of Alzheimer's disease (AD) even after adjustment for age. Though transgenic mouse models of AD develop AD-related amyloid beta (Abeta) and/or tau pathology, gender differences have not b
Autor:
Maki Kuwahara, Masahiro Ikesue, Masaaki Abe, Kazunori Kajino, Tegexibaiyin Wang, Yoshiaki Hagiwara, Hiroaki Mitani, Okio Hino, Masahiro Maeda, Masayoshi Yokoyama, Masayuki Nakaishi, Yuko Horikoshi-Sakuraba, Shigeyuki Kon, Tatsuya Segawa
Publikováno v:
Cancer science. 98(5)
By representational difference analysis, we previously identified the rat Erc (Expressed in renal carcinoma) gene that was more abundantly expressed in the renal carcinoma tissues of Eker rats than in the rat normal kidney. In this study, we raised a