Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Yuko Arita"'
Autor:
Natalia Martin-Orozco, Noah Vale, Alan Mihic, Talya Amor, Lawrence Reiter, Yuko Arita, Reuben Samson, Queenie Hu, Anne-Claude Gingras, Bradley Thomas Sorenson, Eric Gates Marcusson, Piyush Patel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Access to vaccines against SARS-CoV-2 virus was limited in poor countries during the COVID-19 pandemic. Therefore, a low-cost mRNA vaccine, PTX-COVID19-B, was produced and evaluated in a Phase 1 trial. PTX-COVID19-B encodes Spike protein D61
Externí odkaz:
https://doaj.org/article/80d10b4741c34db6a8a02e65ad94a2ce
Autor:
Yuko Arita, Griffin Kim, Zhijian Li, Helena Friesen, Gina Turco, Rebecca Y Wang, Dale Climie, Matej Usaj, Manuel Hotz, Emily H Stoops, Anastasia Baryshnikova, Charles Boone, David Botstein, Brenda J Andrews, R Scott McIsaac
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 6, Pp n/a-n/a (2021)
Abstract The ability to switch a gene from off to on and monitor dynamic changes provides a powerful approach for probing gene function and elucidating causal regulatory relationships. Here, we developed and characterized YETI (Yeast Estradiol strain
Externí odkaz:
https://doaj.org/article/e823bfdfa6794a8b99835ae6fd0838ee
Autor:
Shinichi Nishimura, Kumiko Ishii, Kunihiko Iwamoto, Yuko Arita, Shigeki Matsunaga, Yoshiko Ohno-Iwashita, Satoshi B Sato, Hideaki Kakeya, Toshihide Kobayashi, Minoru Yoshida
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83716 (2013)
Cholesterol plays important roles in biological membranes. The cellular location where cholesterol molecules work is prerequisite information for understanding their dynamic action. Bioimaging probes for cholesterol molecules would be the most powerf
Externí odkaz:
https://doaj.org/article/417d1998049e4eb59960a9264088c916
Autor:
Natalia Martin Orozco, Noah Vale, Alan Mihic, Talya Amor, Lawrence Reiter, Yuko Arita, Reuben Samson, Queenie Hu, Anne-Claude Gingras, Brad Sorenson, Eric G. Marcusson, Piyush Patel
PTX-COVID19-B mRNA vaccine encodes for SARS-CoV-2 Spike protein G614 variant and lacks the proline-proline (986-987 position) mutation present in other COVID-19 vaccines. This Phase 1 observer-blinded, randomized, placebo-controlled, ascending dose s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f319614965744cc4cff7bf46d3a66ee3
https://doi.org/10.1101/2022.05.06.22274690
https://doi.org/10.1101/2022.05.06.22274690
Autor:
Darios Getahun, Samantha Sheller-Miller, Richard J. Jones, Ramkumar Menon, Yuko Arita, Enkhtuya Radnaa, Morgan R. Peltier
Publikováno v:
Placenta
Introduction Exosomes are intercellular signaling vesicles whose cargo reflects the physiological status of the cell of their origin and can regulate gene expression in other tissues. Polybrominated diphenyl ethers (PBDEs) and bisphenols (A [BPA], Te
Autor:
Jun Liu, Patrick Budylowski, Reuben Samson, Bryan D. Griffin, Giorgi Babuadze, Bhavisha Rathod, Karen Colwill, Jumai A. Abioye, Jordan A. Schwartz, Ryan Law, Lily Yip, Sang Kyun Ahn, Serena Chau, Maedeh Naghibosadat, Yuko Arita, Queenie Hu, Feng Yun Yue, Arinjay Banerjee, W. Rod Hardy, Karen Mossman, Samira Mubareka, Robert A. Kozak, Michael S. Pollanen, Natalia Martin Orozco, Anne-Claude Gingras, Eric G. Marcusson, Mario A. Ostrowski
Publikováno v:
Science Advances
Safe and effective vaccines are needed to end the COVID-19 pandemic. Here, we report the preclinical development of a lipid nanoparticle–formulated SARS-CoV-2 mRNA vaccine, PTX-COVID19-B. PTX-COVID19-B was chosen among three candidates after the in
Publikováno v:
Journal of Reproductive Immunology. 154:103737
Globally, ∼50 % of women smoke during pregnancy and the prevalence of vaping is increasing among women of reproductive age. However, the health effects of vaping during pregnancy are largely unknown. This study examined the effects of e-cig constit
Autor:
Heidi Wood, Bhavisha Rathod, Kathy Manguiat, Nazrana Haq, Yves Durocher, Mohammad Mozafarihashjin, Shiva Barati, Alyssia Robinson, Mario A. Ostrowski, Gary Chao, Julia Garnham Takaoka, Allison McGeer, Anne-Claude Gingras, Mariam Iskilova, Kento T. Abe, Sharon E. Straus, Jennifer L. Gommerman, Salma Sheikh-Mohamed, Queenie Hu, Reuben Samson, Karen Green, Lois Gilbert, W. Rod Hardy, Aimee Paterson, Adrian Pasculescu, Yuko Arita, Alyson Takaoka, Eric G. Marcusson, Jenny Wang, Keelia Quinn De Launay, Karen Colwill, Angel Li, Christine Fahim, Mahya Fazel-Zarandi
Prioritizing Ontario’s long-term care home (LTCH) residents for vaccination against severe acute respiratory syndrome coronavirus 2 has drastically reduced their disease burden; however, recent LTCH outbreaks of variants of concern (VOCs) have rais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ea8d80fc53d6717bdc7e9bdd962ab94
https://doi.org/10.1101/2021.08.06.21261721
https://doi.org/10.1101/2021.08.06.21261721
Autor:
Bryan D Griffin, Eric G. Marcusson, Anne-Claude Gingras, Jun Liu, Feng Yun Yue, Yuko Arita, Maedeh Naghibosadat, Patrick Budylowski, Karen L. Mossman, Queenie Hu, Reuben Samson, Samira Mubareka, Jumai A Abioye, Sang Kyun Ahn, Robert A. Kozak, Mario A. Ostrowski, Michael S. Pollanen, Jordan A. Schwartz, Serena Chau, Lily Yip, Natalia Martin Orozco, Karen Colwill, Giorgi Babuadze, Arinjay Banerjee, Ryan Law, Bhavisha Rathod
Safe and effective vaccines are needed to end the COVID-19 pandemic caused by SARS-CoV-2. Here we report the preclinical development of a lipid nanoparticle (LNP) formulated SARS-CoV-2 mRNA vaccine, PTX-COVID19-B. PTX-COVID19-B was chosen among three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef69824ce9b9d36b5c54228112ebe79
https://doi.org/10.1101/2021.05.11.443286
https://doi.org/10.1101/2021.05.11.443286
Autor:
Brenda J. Andrews, Gina Turco, Charles Boone, Helena Friesen, Dale Climie, Yuko Arita, Manuel Hotz, Matej Usaj, R. Scott McIsaac, Emily H Stoops, Zhijian Li, Griffin Kim, Rebecca Y Wang, Anastasia Baryshnikova, David Botstein
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology, Vol 17, Iss 6, Pp n/a-n/a (2021)
Molecular Systems Biology, Vol 17, Iss 6, Pp n/a-n/a (2021)
The ability to switch a gene from off to on and monitor dynamic changes provides a powerful approach for probing gene function and elucidating causal regulatory relationships. Here, we developed and characterized YETI (Yeast Estradiol strains with Ti